Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation

A microbial symbiosis factor prevents intestinal inflammatory disease

2008 • 2,187 citations

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

2013 • 1,922 citations

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

2001 • 1,824 citations

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

2013 • 1,729 citations

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

2010 • 1,047 citations

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer

2001 • 1,020 citations

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

2012 • 910 citations

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

2009 • 769 citations

Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

2009 • 743 citations

A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

2003 • 610 citations

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

2007 • 610 citations

Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection

2004 • 509 citations

Tumor-infiltrating dendritic cell precursors recruited by a β-defensin contribute to vasculogenesis under the influence of Vegf-A

2004 • 430 citations

Tumor-Infiltrating γδ T Cells Suppress T and Dendritic Cell Function via Mechanisms Controlled by a Unique Toll-like Receptor Signaling Pathway

2007 • 381 citations

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

2011 • 345 citations

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

2012 • 308 citations

Ovarian cancer progression is controlled by phenotypic changes in dendritic cells

2012 • 292 citations

Toll-like receptor polymorphisms and susceptibility to human disease

2008 • 262 citations

Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells

2011 • 241 citations

Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease

2012 • 236 citations

Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease

2006 • 201 citations

Toll-Like Receptor Polymorphisms and Susceptibility to Urinary Tract Infections in Adult Women

2009 • 201 citations

Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity

2009 • 200 citations

Prevalence of CARD15/NOD2 Mutations in Caucasian Healthy People

2007 • 191 citations

A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia

2011 • 42 citations

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer

2014 • 23 citations

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer

2014 • 7 citations