Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

1988 • 2,740 citations

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

1980 • 2,722 citations

Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.

1987 • 2,245 citations

TRIAL OF TISSUE PLASMINOGEN ACTIVATOR FOR MORTALITY REDUCTION IN ACUTE MYOCARDIAL INFARCTION

1988 • 1,161 citations

Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase

1988 • 992 citations

Comparison of Invasive and Conservative Strategies after Treatment with Intravenous Tissue Plasminogen Activator in Acute Myocardial Infarction

1989 • 991 citations

A Randomized Trial of Immediate versus Delayed Elective Angioplasty after Intravenous Tissue Plasminogen Activator in Acute Myocardial Infarction

1987 • 964 citations

Thrombolysis inMyocardial Infarction (TIMI) Trial, Phase I:acomparison between intravenous tissue plasminogen activator andintravenous streptokinase*

1987 • 751 citations

A Prospective Trial of Intravenous Streptokinase in Acute Myocardial Infarction (I.S.A.M.)

1986 • 705 citations

A HAEMATOLOGIST

1989 • 567 citations

HOME OR AWAY?

1964 • 508 citations

Thrombolysis in myocardial infarction (TIMI) trial: Phase I. A comparison between intravenous tissue plasminogen activator and intravenous streptokinase

1988 • 475 citations

Evidence Favoring the Use of Anticoagulants in the Hospital Phase of Acute Myocardial Infarction

1977 • 439 citations

Intravenous tissue plasminogen activator and size of infarct, left ventricular function, and survival in acute myocardial infarction.

1988 • 386 citations

Exact Significance Testing to Establish Treatment Equivalence with Ordered Categorical Data

1984 • 343 citations

Rethrombosis after reperfusion with streptokinase: importance of geometry of residual lesions.

1984 • 322 citations

Acute coronary reocclusion after thrombolysis with recombinant human tissue-type plasminogen activator: prevention by a maintenance infusion.

1986 • 302 citations

Effects of Intracoronary Streptokinase and Intracoronary Nitroglycerin Infusion on Coronary Angiographic Patterns and Mortality in Patients with Acute Myocardial Infarction

1984 • 288 citations

A randomized controlled trial of intravenous tissue plasminogen activator and early intravenous heparin in acute myocardial infarction.

1989 • 276 citations

USE AND ABUSE OF ELECTROENCEPHALOGRAPHY.

1964 • 252 citations

RANDOMISED CONTROLLED TRIAL OF SUBCUTANEOUS CALCIUM-HEPARIN IN ACUTE MYOCARDIAL INFARCTION

1989 • 221 citations

Coronary arterial thrombolysis with combined infusion of recombinant tissue-type plasminogen activator and urokinase in patients with acute myocardial infarction.

1988 • 203 citations

Multicenter reperfusion trial of intravenous anisoylated plasminogen streptokinase activator complex (APSAC) in acute myocardial infarction: Controlled comparison with intracoronary streptokinase

1988 • 145 citations

Coronary perfusion during acute myocardial infarction with a combined therapy of coronary angioplasty and high-dose intravenous streptokinase.

1988 • 125 citations

Pharmacodynamics of thrombolysis with recombinant tissue-type plasminogen activator. Correlation with characteristics of and clinical outcomes in patients with acute myocardial infarction. The TAMI Study Group.

1989 • 117 citations

Acute coronary thrombolysis with recombinant human tissue-type plasminogen activator: Initial patency and influence of maintained infusion on reocclusion rate

1987 • 115 citations

Antithrombotic therapy in cardiac disease. An emerging approach based on pathogenesis and risk.

1989 • 103 citations

Late thrombolytic therapy preserves left ventricular function in patients with collateralized total coronary occlusion: Primary end point findings of the second mount sinai-new york university reperfusion trial

1989 • 102 citations

Factors influencing reocclusion after coronary thrombolysis for acute myocardial infarction

1986 • 96 citations

Multicenter trial of intravenous Anisoylated Plasminogen Streptokinase Activator Complex (APSAC) in acute myocardial infarction: Effects on infarct size and left, ventricular function

1989 • 95 citations

A randomized comparison of intravenous heparin with oral aspirin and dipyridamole 24 hours after recombinant tissue-type plasminogen activator for acute myocardial infarction. National Heart Foundation of Australia Coronary Thrombolysis Group.

1991 • 89 citations

Role of heparin after intravenous thrombolytic therapy for acute myocardial infarction

1987 • 85 citations

Randomized factorial trial of high-dose intravenous streptokinase, of oral aspirin and of intravenous heparin in acute myocardial infarction

1987 • 82 citations

A new thrombolytic regimen for acute myocardial infarction using combination half dose tissue-type plasminogen activator with full dose streptokinase: A pilot study

1989 • 60 citations

Antithrombotic therapy for acute myocardial infarction: mechanisms and prevention of deep venous, left ventricular, and coronary artery thromboembolism.

1986 • 44 citations

Hemorrhage vs Rethrombosis After Thrombolysis for Acute Myocardial Infarction

1986 • 28 citations

Heparin versus aspirin after recombinant tissue plasminogen activator therapy in myocardial infarction: A randomized trial

1990 • 26 citations

A randomized pilot trial of brief versus prolonged heparin after successful reperfusion in acute myocardial infarction

1990 • 19 citations

Myocardial reperfusion: Is it ever too late?

1989 • 16 citations

Heparin and infarct coronary artery patency after streptokinase in acute myocardial infarction

1990 • 15 citations

Review: Thrombolytic Therapy for Patients with Acute Myocardial Infarction

1987 • 2 citations

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