Potential role of active vitamin D in retarding the progression of chronic kidney disease

Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

2001 • 7,165 citations

Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

2001 • 5,812 citations

Vitamin D

1979 • 3,814 citations

Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study

2000 • 2,127 citations

1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system

2002 • 1,778 citations

Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy

1997 • 1,775 citations

Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: Results of the study to evaluate early kidney disease

2006 • 1,440 citations

Pathophysiology of Progressive Nephropathies

1998 • 1,250 citations

Facilitative glucose transporters

1994 • 1,103 citations

1α,25-Dihydroxyvitamin D3 Has a Direct Effect on Naive CD4+ T Cells to Enhance the Development of Th2 Cells

2001 • 1,091 citations

Epithelial to Mesenchymal Transition in Renal Fibrogenesis

2004 • 1,036 citations

1,25-Dihydroxyvitamin D ₃ Receptors in Human Leukocytes

1983 • 1,030 citations

RETRACTED: Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trial

2003 • 974 citations

Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL

2004 • 956 citations

Extrarenal Expression of 25-Hydroxyvitamin D₃-1α-Hydroxylase¹

2001 • 847 citations

Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling

2001 • 783 citations

Albuminuria, a Therapeutic Target for Cardiovascular Protection in Type 2 Diabetic Patients With Nephropathy

2004 • 729 citations

Expression of 1,25-Dihydroxyvitamin D3 Receptor in the Immune System

2000 • 694 citations

Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems

2004 • 565 citations

Progression, remission, regression of chronic renal diseases

2001 • 552 citations

Chemokines, Chemokine Receptors, and Renal Disease

2000 • 492 citations

Transcription factor-κB (NF-κB) and renal disease

2001 • 474 citations

The coming of age of 1,25-dihydroxyvitamin D3 analogs as immunomodulatory agents

2002 • 469 citations

Convergence of Transforming Growth Factor-β and Vitamin D Signaling Pathways on SMAD Transcriptional Coactivators

1999 • 442 citations

Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy

2001 • 378 citations

Antiproteinuric effect of oral paricalcitol in chronic kidney disease

2005 • 371 citations

Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

2003 • 341 citations

Effect of alfacalcidol on natural course of renal bone disease in mild to moderate renal failure

1995 • 313 citations

Paricalcitol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy

2006 • 283 citations

Podocytes Respond to Mechanical Stress In Vitro

2001 • 276 citations

Overexpression of glucose transporters in rat mesangial cells cultured in a normal glucose milieu mimics the diabetic phenotype.

1995 • 269 citations

RENAL TUBULE ALBUMIN TRANSPORT

2004 • 257 citations

Disruption of Nuclear Vitamin D Receptor Gene Causes Enhanced Thrombogenicity in Mice

2004 • 254 citations

Effect of 1,25(OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats

1998 • 248 citations

1,25-Dihydroxyvitamin D ₃ Attenuates of Expression of Experimental Murine Lupus of MRL/1 Mice

1992 • 243 citations

Serum levels of 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D in nondialyzed patients with chronic renal failure

1999 • 234 citations

1,25-Dihydroxyvitamin D₃decreases podocyte loss and podocyte hypertrophy in the subtotally nephrectomized rat

2004 • 221 citations

Oral Sulodexide Reduces Albuminuria in Microalbuminuric and Macroalbuminuric Type 1 and Type 2 Diabetic Patients

2002 • 190 citations

DETERIORATION OF RENAL FUNCTION DURING TREATMENT OF CHRONIC RENAL FAILURE WITH 1,25- DIHYDROXYCHOLECALCIFEROL

1978 • 181 citations

Down-regulation of NF-kappa B protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3.

1995 • 180 citations

Doxercalciferol safely suppresses PTH levels in patients with secondary hyperparathyroidism associated with chronic kidney disease stages 3 and 4

2004 • 169 citations

Structural and functional characterization of the mouse hepatocyte growth factor gene promoter.

1994 • 161 citations

Role of nitric oxide in diabetic nephropathy

2004 • 154 citations

A Vitamin D Analog Ameliorates Glomerular Injury on Rat Glomerulonephritis

2001 • 138 citations

Biochemical and Molecular Mechanisms in the Development of Diabetic Vascular Complications

1996 • 128 citations

Distinctive dendritic cell modulation by vitamin D3 and glucocorticoid pathways

2002 • 123 citations

Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent.

2000 • 121 citations

<scp>D</scp>-Glucose Stimulates Mesangial Cell GLUT1 Expression and Basal and IGF-I–Sensitive Glucose Uptake in Rat Mesangial Cells: Implications for Diabetic Nephropathy

1997 • 118 citations

Effects of 1,25(OH)2D3 in experimental mesangial proliferative nephritis in rats

2001 • 116 citations

TGF-β1 stimulates glucose uptake by enhancing GLUT1 expression in mesangial cells

1999 • 103 citations

1,25-dihydroxyvitamin D3 inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression

2005 • 102 citations

Impaired myogenic responsiveness of renal microvessels in Dahl salt-sensitive rats.

1992 • 102 citations

An extremely high dose of losartan affords superior renoprotection in the remnant model

2005 • 101 citations

TGF-β impairs renal autoregulation via generation of ROS

2005 • 101 citations

The changing epidemiology of diabetic microangiopathy in type 1 diabetes

2005 • 98 citations

CONTROLLED TRIAL OF 1α-HYDROXYCHOLECALCIFEROL IN CHRONIC RENAL FAILURE

1976 • 96 citations

Mechanism of vitamin D action and its regulation

1998 • 91 citations

Calcitriol modulates in vivo and in vitro cytokine production: A role for intracellular calcium

1998 • 89 citations

Low-dose calcitriol prevents the rise in 1,84 iPTH without affecting serum calcium and phosphate in patients with moderate renal failure (prospective placebo-controlled multicentre trial)

1995 • 85 citations

GLUT-1 Overexpression

2003 • 85 citations

Gene expression of vitamin D hydroxylase and megalin in the remnant kidney of nephrectomized rats

2003 • 85 citations

F-actin fiber distribution in glomerular cells: Structural and functional implications

2000 • 84 citations

Effect of 18 months of treatment with alfacalcidol on bone in patients with mild to moderate chronic renal failure

2004 • 80 citations

22-Oxacalcitriol prevents progressive glomerulosclerosis without adversely affecting calcium and phosphorus metabolism in subtotally nephrectomized rats

2002 • 79 citations

Glucose transporters of the glomerulus and the implications for diabetic nephropathy.

1997 • 76 citations

Partial prevention of active Heymann nephritis by 1α, 25 dihydroxyvitamin D3

1993 • 75 citations

Current concepts of renal hemodynamics in diabetes

1995 • 74 citations

1,25-(OH2)D3 Alters the Transforming Growth Factor β Signaling Pathway in Renal Tissue

2001 • 66 citations

Central role of VDR conformations for understanding selective actions of vitamin D3 analogues

2001 • 66 citations

Vitamin D receptor and analogs

2004 • 64 citations

Update on vitamin D and its newer analogues: Actions and rationale for treatment in chronic renal failure

2002 • 63 citations

Association between the GLUT1 gene polymorphism and the risk of diabetic nephropathy: a meta-analysis

2005 • 63 citations

Vitamin D analogues

1998 • 62 citations

Pathogenic, clinical, and therapeutic aspects of secondary hyperparathyroidism in chronic renal failure

1998 • 62 citations

Altered gene expression profile in the kidney of vitamin D receptor knockout mice

2003 • 55 citations

1,25-Dihydroxyvitamin D3 up-regulates the renal vitamin D receptor through indirect gene activation and receptor stabilization

2004 • 51 citations

The mechanisms underlying altered vascular resistance of glomerular afferent and efferent arterioles in diabetic nephropathy

2003 • 50 citations

A Retrospective Evaluation of 1,25-Dihydroxyvitamin D&lt;sub&gt;3&lt;/sub&gt; and Its Potential Effects on Renal Allograft Function

2002 • 49 citations

A placebo-controlled trial to evaluate immunomodulatory effects of paricalcitol

2001 • 48 citations

P38 mitogen-activated protein kinase mediates hexosamine-induced TGFβ1 mRNA expression in human mesangial cells

2003 • 45 citations

Antisense GLUT-1 protects mesangial cells from glucose induction of GLUT-1 and fibronectin expression

2001 • 45 citations

Diminished NF-κB activation and PDGF-B expression in glomerular endothelial cells subjected to chronic shear stress

2003 • 37 citations

Actions of 1,25-Dihydroxyvitamin D3 on Human Mesangial Cells

1991 • 30 citations

Renal bradykinin receptors: localisation, transduction pathways and molecular basis for a possible pathological role (review).

1999 • 20 citations

1,25-Dihydroxyvitamin D&lt;sub&gt;3&lt;/sub&gt; and the Synthetic Vitamin D Analogue, KH 1060, Modulate the Growth of Mouse Proximal Tubular Cells

1996 • 17 citations

human mesangial cells

1994 • 8 citations

Deleted Work

1955 • 0 citations