Effect of heparin and related glycosaminoglycan on PDGF-induced lung fibroblast proliferation, chemotactic response and matrix metalloproteinases activity

The biology of platelet-derived growth factor

1986 • 2,036 citations

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

1989 • 1,151 citations

Platelet-derived growth factor in chemotactic for fibroblasts.

1982 • 744 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis

1987 • 420 citations

Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membrane.

1996 • 416 citations

Platelet-derived growth factor in idiopathic pulmonary fibrosis.

1990 • 376 citations

Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer.

1986 • 348 citations

Morphological studies of bronchial mucosal biopsies from asthmatics before and after ten years of treatment with inhaled steroids

1988 • 341 citations

Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders.

1979 • 266 citations

Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase.

1993 • 233 citations

ROLE OF THE CLOTTING SYSTEM IN CELL-MEDIATED HYPERSENSITIVITY

1973 • 208 citations

Collagenase in the Lower Respiratory Tract of Patients with Idiopathic Pulmonary Fibrosis

1979 • 205 citations

Hyperreactive Site in the Airway Tree of Asthmatic Patients Revealed by Thickening of Bronchial Muscles: A Morphometric Study

1990 • 204 citations

Extracellular matrix in normal and fibrotic human lungs.

1985 • 200 citations

Inhibition of T lymphocyte heparanase by heparin prevents T cell migration and T cell‐mediated immunity

1990 • 153 citations

Heparin Inhibits the Immediate Response to Antigen in the Skin and Lungs of Allergic Subjects

1993 • 129 citations

Human skin chymotrypsin-like proteinase chymase. Subcellular localization to mast cell granules and interaction with heparin and other glycosaminoglycans.

1987 • 118 citations

Co-culture of human breast adenocarcinoma MCF-7 cells and human dermal fibroblasts enhances the production of matrix metalloproteinases 1, 2 and 3 in fibroblasts

1995 • 106 citations

Concentration, biosynthesis and degradation of collagen in idiopathic pulmonary fibrosis.

1986 • 98 citations

Induction of fibroblast 92 kDa gelatinase/type iv collagenase expression by direct contact with metastatic tumor cells

1994 • 84 citations

[20] Vertebrate collagenases

1982 • 81 citations

Degradation of sulfated proteoglycans in the subendothelial extracellular matrix by human platelet heparitinase.

1984 • 78 citations

Interleukin-1 and Transforming Growth Factor-α: Synergistic Stimulation of Metalloproteinases, PGE2, and Proliferation in Human Fibroblasts

1994 • 77 citations

Human arterial smooth muscle cells in culture

1988 • 74 citations

Quantitative in vitro assay for tumor cell invasion through extracellular matrix or into protein gels.

1988 • 59 citations

Apposition of fibroblasts to mast cells and lymphocytes in normal human lung and in cryptogenic fibrosing alveolitis. Ultrastructure and cell perimeter measurements

1992 • 47 citations

Stimulation of human synovial fibroblast DNA synthesis by platelet-derived growth factor and fibroblast growth factor. Differences to the activation by IL-1.

1989 • 46 citations

The effect of heparin and related proteoglycans on allergen and PAF-induced eosinophil infiltration.

1993 • 39 citations

Effect of heparin and a low‐molecular weight heparinoid on PAF‐induced airway responses in neonatally immunized rabbits

1993 • 37 citations

Inhibition of serum‐induced proliferation of bovine tracheal smooth muscle cells in culture by heparin and related glycosaminoglycans

1995 • 31 citations

Mast cells and idiopathic lung fibrosis.

1990 • 12 citations