Feature article: are neurons lost from the primate cerebral cortex during normal aging?

Neuropathological stageing of Alzheimer-related changes

1991 • 14,533 citations

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis

1988 • 2,948 citations

The unbiased estimation of number and sizes of arbitrary particles using the disector

1984 • 2,539 citations

The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

1988 • 2,498 citations

Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus

1986 • 1,978 citations

Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease

1996 • 1,734 citations

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

1997 • 1,395 citations

Neocortical neuron number in humans: Effect of sex and age

1997 • 1,197 citations

Unbiased stereological estimation of the number of neurons in the human hippocampus

1990 • 1,146 citations

Methods for determining numbers of cells and synapses: A case for more uniform standards of review

1996 • 981 citations

New stereological methods for counting neurons

1993 • 951 citations

The visual field representation in striate cortex of the macaque monkey: Asymmetries, anisotropies, and individual variability

1984 • 934 citations

Neuron numbers and dendritic extent in normal aging and Alzheimer's disease

1987 • 769 citations

Neocortical cell counts in normal human adult aging

1987 • 676 citations

Preserved neuron number in the hippocampus of aged rats with spatial learning deficits.

1996 • 635 citations

Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia

1977 • 628 citations

Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex

1955 • 624 citations

Regionally specific loss of neurons in the aging human hippocampus

1993 • 612 citations

Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease

1997 • 505 citations

The topography and variability of the primary visual cortex in man

1974 • 423 citations

Neurobiological Bases of Age-Related Cognitive Decline in the Rhesus Monkey

1996 • 340 citations

The total number of neurons in the human neocortex unbiasedly estimated using optical disectors

1990 • 284 citations

Cell counts in human cerebral cortex in normal adults throughout life using an image analysing computer

1980 • 267 citations

The Effects of Aging on Area 46 of the Frontal Cortex of the Rhesus Monkey

1994 • 237 citations

THE DENSITY OF SYNAPSES AND NEURONS IN NORMAL, MENTALLY DEFECTIVE AND AGEING HUMAN BRAINS

1975 • 223 citations

Neuron Loss in the Aging Visual Cortex of Man

1980 • 198 citations

Topography of brain atrophy during normal aging and alzheimer's disease

1996 • 187 citations

Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys.

1996 • 177 citations

No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type

1994 • 167 citations

The significance of morphometric procedures in the investigation of age changes in cytoarchitectonic structures of human brain.

1984 • 163 citations

Effects of aging on the size, density, and number of rhesus monkey lateral geniculate neurons

1993 • 134 citations

Hippocampal aging in rats: A morphometric study of multiple variables in semithin sections

1981 • 125 citations

Absolute number of neurons and thickness of the cerebral cortex during aging, senile and vascular dementia, and Pick's and Alzheimer's diseases

1973 • 123 citations

Preserved Number of Entorhinal Cortex Layer II Neurons in Aged Macaque Monkeys

1997 • 119 citations

Changes in volume, surface estimate, three-dimensional shape and total number of neurons of the human primary visual cortex from midgestation until old age

1994 • 119 citations

Structural Changes in the Aging Nervous System

2015 • 114 citations

Sensory neuron number in neonatal and adult rats estimated by means of stereologic and profile-based methods

1997 • 113 citations

Effects of aging on the neurons within area 17 of rhesus monkey cerebral cortex

1989 • 99 citations

Localization of cellular changes within multimodal sensory regions in aged monkey brain: Possible implications for age-related cognitive loss☆

1980 • 99 citations

Visual cortex in Alzheimer's disease: Occurencee of neuronal death and glial proliferation, and correlation with pathological hallmarks

1994 • 89 citations

Neuronal population of area 4 during the life span of the rhesus monkey

1990 • 67 citations

Effects of aging on the densities, numbers, and sizes of retinal ganglion cells in rhesus monkey

1996 • 63 citations

Development of blobs in the visual cortex of macaques

1993 • 61 citations

A further evaluation of the effect of age on striate cortex of the rhesus monkey

1997 • 52 citations

Aging and the Meynert cells in rhesus monkey primary visual cortex

1993 • 51 citations

Quantitative Histological Studies on Aging Changes in Cerebral Cortex of Rhesus Monkey and Albino Rat with Notes on Effects of Prolonged Low-Dose Ionizing Irradiation in the Rat

1973 • 50 citations

Brain Weight Does Not Decrease with Age in Adult Rhesus Monkeys

1998 • 48 citations

Effects of aging on numbers and sizes of neurons in histochemically defined subregions of monkey striate cortex

1997 • 42 citations

Comparing age-related changes in the basal forebrain and hippocampus of the rhesus monkey

1993 • 41 citations

Morphological analyses of the brains of behaviorally characterized aged nonhuman primates

1993 • 37 citations

Changes in Microanatomy, Neurocytology and Fine Structure with Aging

1975 • 29 citations

Volumetric asymmetry in the human striate cortex

1985 • 26 citations

Novel inclusion bodies in Betz cells of cortical area 4 of aged rhesus monkeys

1992 • 14 citations

Lack of neocortical nerve cell loss in Alzheimer's disease: Reality or methodological artifact

1994 • 6 citations

Deleted Work

1955 • 0 citations