FDA Drug Approval Summary: Bevacizumab (Avastin®) as Treatment of Recurrent Glioblastoma Multiforme

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

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Response criteria for phase II studies of supratentorial malignant glioma.

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Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas

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Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma

2008 • 1,520 citations

Bevacizumab Plus Irinotecan in Recurrent Glioblastoma Multiforme

2007 • 1,368 citations

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas

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A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma

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A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse

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Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

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Interstitial Chemotherapy with Carmustine-loaded Polymers for High-grade Gliomas: A Randomized Double-blind Study

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Effect of bevacizumab on radiation necrosis of the brain

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MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy

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Treatment with bevacizumab and irinotecan for recurrent high‐grade glial tumors

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Phase III Study Comparing Three Cycles of Infusional Carmustine and Cisplatin Followed by Radiation Therapy With Radiation Therapy and Concurrent Carmustine in Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme: Eastern Cooperative Oncology Group Trial 2394

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Intracavitary VEGF, bFGF, IL-8, IL-12 levels in primary and recurrent malignant glioma.

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MRI in treatment of adult gliomas

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Time course of imaging changes of GBM during extended bevacizumab treatment

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Current Chemotherapy for Glioblastoma

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Bevacizumab Reverses Cerebral Radiation Necrosis

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Interobserver variability in the radiological assessment of response to chemotherapy in glioma

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Irinotecan and bevacizumab in progressive primary brain tumors, an evaluation of efficacy and safety

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Bevacizumab: A Treatment Option for Recurrent Glioblastoma Multiforme

2008 • 39 citations