Quinolinic Acid Concentrations in Brain and Cerebrospinal Fluid of Patients with Intractable Complex Partial Seizures

Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS

1981 • 728 citations

Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase.

1986 • 372 citations

l-Kynurenine Its synthesis and possible regulatory function in brain

1980 • 299 citations

Activation of N-methyl-D-aspartate receptors parallels changes in cellular and synaptic properties of dentate gyrus granule cells after kindling

1988 • 261 citations

Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system.

1983 • 209 citations

Interacting neurotransmitter systems. A non-experimental approach to the 5hiaa-hva correlation in human CSF

1986 • 202 citations

Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome

1989 • 190 citations

Identification of quinolinic acid in rat and human brain tissue

1983 • 182 citations

Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice

1978 • 181 citations

SURGERY OF CONGENITAL HEART DISEASES

1947 • 137 citations

The NMDA receptor antagonist 2-amino-5-phosphonovalerate blocks stimulus train-induced epileptogenesis but not epileptiform bursting in the rat hippocampal slice

1987 • 136 citations

Excitatory amino acids are elevated in human epileptic cerebral cortex

1988 • 128 citations

Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: Effects of systemic l-tryptophan administration on brain and blood quinolinic acid concentrations

1988 • 126 citations

Synthesis of Quinolinic Acid by 3‐Hydroxyanthranilic Acid Oxygenase in Rat Brain Tissue In Vitro

1986 • 124 citations

Studies on the disposition of quinolinic acid after intracerebral or systemic administration in the rat

1984 • 115 citations

In Vivo Brain Dialysis of Amino Acids and Simultaneous EEG Measurements Following Intrahippocampal Quinolinic Acid Injection: Evidence for a Dissociation Between Neurochemical Changes and Seizures

1985 • 108 citations

Convulsant action of intracerebroventricularly administered l-kynurenine sulphate, quinolinic acid and other derivatives of succinic acid, and effects of amino acids: structure-activity relationships

1982 • 96 citations

Rat 3‐Hydroxyanthranilic Acid Oxygenase: Purification from the Liver and Immunocytochemical Localization in the Brain

1987 • 80 citations

Systemic endotoxin increasesl-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex

1989 • 76 citations

MANIPULATION OF BRAIN SEROTONIN IN THE TREATMENT OF MYOCLONUS

1975 • 76 citations

Quinolinic Acid Phosphoribosyltransferase in Rat Brain

1985 • 72 citations

Quinolinic‐Phosphoribosyl Transferase Activity is Decreased in Epileptic Human Brain Tissue

1988 • 64 citations

Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists

1988 • 49 citations

(18O)quinolinic acid: Its esterification without back exchange for use as internal standard in the quantification of brain and CSF quinolinic acid

1988 • 47 citations

Quinolinic acid phosphoribosyltransferase: preferential glial localization in the rat brain visualized by immunocytochemistry.

1987 • 46 citations

Glutamate and malate dehydrogenase activities in Joseph disease and olivopontocerebellar atrophy

1987 • 43 citations

Organ Distribution of Rat Kynureninase and Changes of Its Activity during Development

1988 • 42 citations

Systemic Lipopolysaccharide and Pokeweed Mitogen Increase Quinolinic Acid Content of Mouse Cerebral Cortex

1988 • 41 citations

4-chloro-3-hydroxyanthranilate inhibits brain 3-hydroxyanthranate oxidase

1988 • 40 citations

Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with progressive myoclonus epilepsy

2009 • 37 citations

Increased quinolinic acid metabolism following neuronal degeneration in the rat hippocampus

1987 • 33 citations

Presence of Kynurenine Hydroxylase in Developing Rat Brain

1981 • 30 citations

Convulsive Activity of α‐Guanidinoglutaric Acid and the Possible Involvement of 5‐Hydroxytryptamine in the α‐Guanidinoglutaric Acid‐Induced Seizure Mechanism

1986 • 29 citations

Studies on kynurenine in human cerebrospinal fluid: Lowered levels in epilepsy

1983 • 23 citations

Neurotransmitter amino acids in epilepsy

1985 • 9 citations