Pregnancy and the Risk of Teratogenicity

Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study

1991 • 3,323 citations

Prevention of neural tube defects: Results of the Medical Research Council vitamin study

1992 • 2,294 citations

Spina Bifida in Infants of Women Treated with Carbamazepine during Pregnancy

1991 • 463 citations

Multi‐institutional Study on the Teratogenicity and Fetal Toxicity of Antiepileptic Drugs: A Report of a Collaborative Study Group in Japan

1980 • 302 citations

The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort.

1992 • 253 citations

Epilepsy, Pregnancy and the Child

1982 • 243 citations

GENETIC PREDISPOSITION TO PHENYTOIN-INDUCED BIRTH DEFECTS

1985 • 220 citations

Teratogenicity of Antiepileptic Drug Combinations with Special Emphasis on Epoxidation (of Carbamazepine)

1984 • 214 citations

Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.

1992 • 161 citations

Teratogenic valproic acid concentrations: Infusion by implanted minipumps vs conventional injection regimen in the mouse

1985 • 156 citations

Alteration of embryonic folate metabolism by valproic acid during organogenesis: implications for mechanism of teratogenesis.

1992 • 155 citations

Spectrum of neural-tube defects in 34 infants prenatally exposed to antiepileptic drugs.

1992 • 153 citations

Intelligence of children of epileptic mothers

1988 • 143 citations

Minor anomalies in offspring of epileptic mothers

1988 • 131 citations

Mechanisms of teratogenesis: folic acid and antiepileptic therapy.

1992 • 130 citations

SPECIFIC COGNITIVE DYSFUNCTION IN CHILDREN WITH EPILEPTIC MOTHERS

1990 • 124 citations

ONCOGENES

1984 • 123 citations

Fetal hydantoin effects

1986 • 114 citations

Valproic acid-induced neural tube defects: Reduction by folinic acid in the mouse

1987 • 95 citations

Valproic acid teratogenicity in mice after various administration and phenobarbital-pretreatment regimens: The parent drug and not one of the metabolites assayed is implicated as teratogen

1986 • 68 citations

Diurnal variation of folate concentrations in mouse embryo and plasma: The protective effect of folinic acid on valproic-acid-induced teratogenicity is time dependent

1991 • 62 citations

Antiepileptic Drugs and Pregnancy

1985 • 58 citations

Prenatal diagnosis of spina bifida aperta after first‐trimester valproate exposure

1992 • 46 citations

The disposition of valproate and its metabolites in the late first trimester and early second trimester of pregnancy in maternal serum, urine, and amniotic fluid: Effect of dose, co-medication, and the presence of spina bifida

1992 • 45 citations

Pharmacogenetics and drug interactions: role in antiepileptic-drug-induced teratogenesis.

1992 • 44 citations

A transient retardation of early postnatal growth in drug-exposed children of epileptic mothers

1989 • 38 citations

The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy

1988 • 13 citations