TP53Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck

A new look at the statistical model identification

1974 • 46,507 citations

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 7,673 citations

Cancer Statistics, 2007

2007 • 7,372 citations

Surfing the p53 network

2000 • 6,487 citations

A Class of $K$-Sample Tests for Comparing the Cumulative Incidence of a Competing Risk

1988 • 4,727 citations

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1990 • 3,896 citations

Asymptotically Efficient Rank Invariant Test Procedures

1972 • 3,392 citations

Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

2000 • 3,004 citations

Analysis of Binary Data

2008 • 2,760 citations

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

1994 • 2,460 citations

Apoptosis - the p53 network

2003 • 1,099 citations

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

2002 • 1,050 citations

Human Papillomavirus Infection as a Risk Factor for Squamous-Cell Carcinoma of the Head and Neck

2001 • 931 citations

Association between Cigarette Smoking and Mutation of the p53 Gene in Squamous-Cell Carcinoma of the Head and Neck

1995 • 664 citations

Assessing TP53 status in human tumours to evaluate clinical outcome

2001 • 646 citations

Human papillomavirus (HPV) in head and neck cancer

2005 • 560 citations

Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck

1998 • 389 citations

The p53 Gene in Breast Cancer: Prognostic Value of Complementary DNA Sequencing Versus Immunohistochemistry

1996 • 387 citations

Exact Significance Testing to Establish Treatment Equivalence with Ordered Categorical Data

1984 • 343 citations

The p53 tumor suppressor participates in multiple cell cycle checkpoints

2006 • 314 citations

Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array

1999 • 233 citations

TP53: a key gene in human cancer

2002 • 184 citations

TP53 mutations and breast cancer prognosis: Particularly poor survival rates for cases with mutations in the zinc‐binding domains

1995 • 179 citations

The p53 network in head and neck cancer

2003 • 158 citations

TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer

1998 • 156 citations

Carcinogenic effect of tobacco smoking and alcohol drinking on anatomic sites of the oral cavity and oropharynx

1992 • 136 citations

Reassessment of theTP53 mutation database in human disease by data mining with a library ofTP53 missense mutations

2004 • 134 citations

Locus-specific mutation databases: pitfalls and good practice based on the p53 experience.

2006 • 133 citations

Immunohistochemical detection of p53 protein accumulation in head and neck cancer: Correlation with p53 gene alterations

1999 • 103 citations

Evaluation of the Performance of a p53 Sequencing Microarray Chip Using 140 Previously Sequenced Bladder Tumor Samples

2000 • 93 citations

Loss of heterozygosity and mutation analysis of the p16 (9p21) and p53 (17p13) genes in squamous cell carcinoma of the head and neck.

1995 • 72 citations

Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: evolution of a model beyond TNM staging

2000 • 68 citations

p53 mutations in head and neck cancer: new data and evaluation of mutational spectra.

1997 • 51 citations

PREDICTIVE FACTORS IN HEAD AND NECK CANCER

1999 • 35 citations