Characterization of an abnormal fibrinogen Osaka V with the replacement of gamma-arginine 375 by glycine. The lack of high affinity calcium binding to D-domains and the lack of protective effect of calcium on fibrinolysis.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Determination of the amino acid sequence of porcine trypsin by sequenator analysis

1973 • 259 citations

Abnormal Plasminogen

1978 • 259 citations

Protective effect of calcium in the plasmin degradation of fibrinogen and fibrin fragments D

1977 • 146 citations

An internal standard for amino acid analyses: S-β-(4-pyridylethyl)-l-cysteine

1970 • 141 citations

Amino acid sequence studies on plasmin-derived fragments of human fibrinogen. Amino-terminal sequences of intermediate and terminal fragments

1975 • 135 citations

Fibrinogen Bethesda: a congenital dysfibrinogenemia with delayed fibrinopeptide release

1971 • 118 citations

[27] Factor XIII (fibrin-stabilizing factor)

1981 • 117 citations

Site-directed mutagenesis of the regulatory light-chain Ca2+/Mg2+ binding site and its role in hybrid myosins

1986 • 112 citations

The Essential Covalent Structure of Human Fibrinogen Evinced by Analysis of Derivatives Formed during Plasmic Hydrolysis

1973 • 110 citations

The binding of calcium to bovine fibrinogen

1977 • 98 citations

Localization of a fibrin polymerization site.

1981 • 97 citations

Localization of a fibrinogen calcium binding site between gamma-subunit positions 311 and 336 by terbium fluorescence.

1985 • 97 citations

Hereditary dysfibrinogenemia in a patient with thrombotic disease

1983 • 95 citations

Purification of human platelet calcium-activated protease. Effect on platelet and endothelial function.

1983 • 95 citations

A new type of congenital dysfibrinogenaemia with defective fibrin lysis—Dusard syndrome: possible relation to thrombosis

1983 • 79 citations

Localization of segments essential for polymerization and for calcium binding in the .gamma.-chain of human fibrinogen

1986 • 77 citations

Influence of Calcium Ion on the Binding of Fibrin Amino Terminal Peptides to Fibrinogen

1981 • 76 citations

High Molecular Weight Derivatives of Human Fibrinogen Produced by Plasmin

1972 • 75 citations

Primary structure of human fibrinogen and fibrin. Isolation and partial characterization of chains of fragment D.

1975 • 70 citations

Nucleotide sequence of the gene for the .gamma. chain of human fibrinogen

1985 • 69 citations

A congenitally abnormal fibrinogen (Vlissingen) with a 6-base deletion in the gamma-chain gene, causing defective calcium binding and impaired fibrin polymerization

1991 • 62 citations

Substitution of gamma Arg-275 by Cys in an abnormal fibrinogen, “fibrinogen Osaka II”. Evidence for a unique solitary cystine structure at the mutation site.

1988 • 59 citations

A gamma methionine-310 to threonine substitution and consequent N-glycosylation at gamma asparagine-308 identified in a congenital dysfibrinogenemia associated with posttraumatic bleeding, fibrinogen Asahi.

1989 • 58 citations

Characterization of peptides cleaved by plasmin from the C-terminal polymerization domain of human fibrinogen.

1985 • 49 citations

Three Abnormal Fibrinogen Variants with the Same Amino Acid Substitution (γ 275 Arg → His): Fibrinogens Bergamo II, Essen and Perugia

1986 • 47 citations

Expression of primary polymerization sites in the D domain of human fibrinogen depends on intact conformation.

1986 • 47 citations

Calcium‐binding properties of human fibrin(ogen) and degradation products

1979 • 43 citations

Characterization of an apparently lower molecular weight gamma-chain variant in fibrinogen Kyoto I. The replacement of gamma-asparagine 308 by lysine which causes accelerated cleavage of fragment D1 by plasmin and the generation of a new plasmin cleavage site.

1988 • 40 citations

Stabilization of the plasmin digestion products of fibrinogen and fibrin by calcium ions

1978 • 39 citations

Fibrinogen Nijmegen : Congenital Dysfibrinogenemia Associated with Impaired t-PA Mediated Plasminogen Activation and Decreased Binding of t-PA

1988 • 38 citations

Recalculation of calcium-binding properties of human and rat fibrin(ogen) and their degradation products

1981 • 38 citations

Characterization of fibrinogen Milano I: amino acid exchange gamma 330 Asp----Val impairs fibrin polymerization

1986 • 37 citations

An apparently higher molecular weight gamma-chain variant in a new congenital abnormal fibrinogen Tochigi characterized by the replacement of gamma arginine-275 by cysteine

1988 • 36 citations

Fibrinogen Nagoya, a Replacement of Glutamine-329 by Arginine in the γ-Chain That Impairs the Polymerization of Fibrin Monomer1

1989 • 32 citations

Localization of a fibrin gamma-chain polymerization site within segment Thr-374 to Glu-396 of human fibrinogen.

1984 • 31 citations

A fibrinogen fragment D (D intermediate) with calcium binding but without anticlotting properties

1982 • 29 citations

Inhibition of fibrin polymerization by fragment D is affected by calcium, Gly-Pro-Arg and Gly-His-Arg

1983 • 28 citations

Plasmic degradation of human fibrinogen III. Molecular model of the plasmin-resistant disulfide knot in monomeric fragment D

1975 • 27 citations

Ca binding of rat fibrinogen and fibrin(ogen) degradation products

1978 • 27 citations

Polymerization defect of fibrinogen Baltimore III due to a gamma Asn308- ---Ile mutation

1990 • 26 citations

Variants of human fibrinogen

1984 • 26 citations

Soluble High-Molecular-Weight E Fragments in the Plasmin-Induced Degradation Products of Cross-Linked Human Fibrin

1975 • 25 citations

Fibrinogen Kyoto III: a congenital dysfibrinogen with a gamma aspartic acid-330 to tyrosine substitution manifesting impaired fibrin monomer polymerization

1989 • 24 citations

Normal Plasmic Cleavage of the γ-Chain Variant of “Fibrinogen Saga” with an Arg–275 to His Substitution

1988 • 23 citations

Fibrinogen Baltimore I: polymerization defect associated with a gamma 292Gly----Val (GGC----GTC) mutation

1990 • 22 citations

Evidence for the localization of a calcium-binding site in the amino-terminal disulphide knot of fibrinogen)

1983 • 21 citations

Fibrinogen Haifa: Fibrinogen Variant with Absence of Protective Effect of Calcium on Plasmin Degradation of Gamma Chains

1987 • 21 citations

Modification of high molecular weight plasmic degradation products of human crosslinked fibrin

1979 • 21 citations

Anticoagulant and calcium-binding properties of high molecular weight derivatives of human fibrinogen (plasmin fragments Y)

1982 • 21 citations

Potential role of the Aα chain in the binding of calcium to human fibrinogen

1982 • 20 citations

A lower molecular weight gamma-chain variant in a congenital abnormal fibrinogen (Kyoto)

1986 • 19 citations

The Polymerization of Fibrin Prepared from Fibrinogen Haifa (γ275Arg→His)

1989 • 17 citations

A subfraction of human fibrinogen with high sialic acid content and elongated gamma chains.

1982 • 15 citations

Fibrinogen baltimore iv: congenital dysfibrinogenemia with a γ275 (ARG → CYS) substitution

1989 • 14 citations

A lower molecular weight gamma-chain variant in a congenital abnormal fibrinogen (Kyoto)

1986 • 13 citations

Fibrinogen Chapel Hill II: Defective in reactions with thrombin, factor XIIIa and plasmin

1982 • 8 citations

Fibrinogen Sevilla, a congenital dysfibrinogenemia characterized by an abnormal monomer aggregation and a defective plasmin lysis

1989 • 5 citations

Fibrinogen houston: A dysfibrinogen exhibiting defective fibrin monomer aggregation and α‐chain cross‐linkages

1980 • 3 citations