The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports
Data up to Jan 2025
Total Citations Per Year
Abstract
References (87)
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Evidence for Association and Genetic Linkage of the Angiotensin-Converting Enzyme Locus With Hypertension and Blood Pressure in Men but Not Women in the Framingham Heart Study
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A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study
2007 • 336 citations
Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study
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Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness
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Association Between Estrogen Receptor α Gene Variation and Cardiovascular Disease
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Sibling Cardiovascular Disease as a Risk Factor for Cardiovascular Disease in Middle-aged Adults
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Genome-wide association with bone mass and geometry in the Framingham Heart Study
2007 • 256 citations
Genome-wide association of sleep and circadian phenotypes
2007 • 244 citations
Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham study
2007 • 205 citations
Genetic and Environmental Contributions to Atherosclerosis Phenotypes in Men and Women
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Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study
2007 • 196 citations
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Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes
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A Genome-Wide Scan for Loci Linked to Plasma Levels of Glucose and HbA1c in a Community-Based Sample of Caucasian Pedigrees
2002 • 187 citations
Genomewide Linkage Analysis to Serum Creatinine, GFR, and Creatinine Clearance in a Community-Based Population
2004 • 172 citations
Genome scan linkage results for longitudinal systolic blood pressure phenotypes in subjects from the Framingham Heart Study
2003 • 168 citations
Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project
2007 • 167 citations
Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study
2004 • 162 citations
Genomewide Linkage Analysis of Body Mass Index across 28 Years of the Framingham Heart Study
2002 • 161 citations
Ignoring Linkage Disequilibrium among Tightly Linked Markers Induces False-Positive Evidence of Linkage for Affected Sib Pair Analysis
2004 • 142 citations
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study
2007 • 139 citations
A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study
2007 • 133 citations
A Genomewide Linkage Study of 1,933 Families Affected by Premature Coronary Artery Disease: The British Heart Foundation (BHF) Family Heart Study
2005 • 127 citations
Framingham Heart Study genome-wide association: results for pulmonary function measures
2007 • 126 citations
Genome Screen for Quantitative Trait Loci Contributing to Normal Variation in Bone Mineral Density: The Framingham Study
2002 • 126 citations
Peakwide Mapping on Chromosome 3q13 Identifies the Kalirin Gene as a Novel Candidate Gene for Coronary Artery Disease
2007 • 123 citations
Genome-wide association with select biomarker traits in the Framingham Heart Study
2007 • 122 citations
Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham Study
2000 • 108 citations
Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study
2007 • 101 citations
Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: Evidence for susceptibility loci on 1q
2005 • 99 citations
Genome-wide association with diabetes-related traits in the Framingham Heart Study
2007 • 94 citations
Genomewide Linkage Analysis for Internal Carotid Artery Intimal Medial Thickness: Evidence for Linkage to Chromosome 12
2004 • 93 citations
Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study
2007 • 91 citations
Estrogen Receptor α Gene Variation Is Associated With Risk of Myocardial Infarction in More Than Seven Thousand Men From Five Cohorts
2006 • 89 citations
A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study
2007 • 86 citations
Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study
2007 • 84 citations
Evidence for Heritability of Abdominal Aortic Calcific Deposits in the Framingham Heart Study
2002 • 78 citations
Common Genetic Variation in Five Thrombosis Genes and Relations to Plasma Hemostatic Protein Level and Cardiovascular Disease Risk
2006 • 77 citations
Heritability of the Ankle-Brachial Index
2006 • 76 citations
Genome-Wide Scan for Pulse Pressure in the National Heart, Lung and Blood Institute’s Framingham Heart Study
2004 • 65 citations
Estrogen receptor-α variants are associated with lipoprotein size distribution and particle levels in women: The Framingham Heart Study
2005 • 56 citations
A genome scan for loci linked to quantitative insulin traits in persons without diabetes: the Framingham Offspring Study
2003 • 54 citations
Genetic Contribution to Biological Aging: The Framingham Study
2004 • 54 citations
Coverage and Characteristics of the Affymetrix GeneChip Human Mapping 100K SNP Set
2006 • 42 citations
Genome-wide linkage analysis to age at natural menopause in a community-based sample: the Framingham Heart Study
2005 • 35 citations
Genome-wide linkage analyses and candidate gene fine mapping for HDL3 cholesterol: the Framingham Study
2005 • 28 citations
Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study
2006 • 27 citations
Description of the Framingham Heart Study data for Genetic Analysis Workshop 13
2003 • 25 citations
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Examining the effect of linkage disequilibrium on multipoint linkage analysis
2005 • 17 citations
Genetic analyses of longitudinal phenotype data: a comparison of univariate methods and a multivariate approach
2003 • 11 citations
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