Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

1987 • 1,021 citations

Elevated Levels of Glucose Transport and Transporter Messenger RNA Are Induced by ras or src Oncogenes

1987 • 789 citations

Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells

1988 • 786 citations

Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.

1986 • 550 citations

Activation of Cell-Specific Expression of Rat Growth Hormone and Prolactin Genes by a Common Transcription Factor

1988 • 525 citations

Pancreatic islet glucose metabolism and regulation of insulin secretion

1986 • 506 citations

Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

1980 • 496 citations

Secretory products of macrophages and their physiological functions

1984 • 494 citations

Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell. Intracellular storage, proteolytic processing, and secretion on stimulation

1983 • 329 citations

Transformation of Rat Fibroblasts by FSV Rapidly Increases Glucose Transporter Gene Transcription

1987 • 286 citations

Transcriptional induction of glucokinase gene by insulin in cultured liver cells and its repression by the glucagon-cAMP system

1989 • 247 citations

Rat glucokinase gene: structure and regulation by insulin.

1989 • 220 citations

An Alternate Promoter in the Glucokinase Gene Is Active in the Pancreatic β Cell

1989 • 210 citations

The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.

1990 • 204 citations

Underexpression of β Cell High K _m Glucose Transporters in Noninsulin-Dependent Diabetes

1990 • 198 citations

Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans.

1989 • 181 citations

The Amino Acid Sequence of Rat Liver Glucokinase Deduced from Cloned cDNA

1989 • 158 citations

Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia.

1990 • 142 citations

Smooth muscle α-actin is a transformation-sensitive marker for mouse NIH 3T3 and Rat-2 cells

1985 • 136 citations

Molecular cloning of glucokinase cDNA. Developmental and dietary regulation of glucokinase mRNA in rat liver.

1987 • 133 citations

Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage.

1986 • 116 citations

Construction and selection of recombinant plasmids containing full-length complementary DNAs corresponding to rat insulins I and II.

1979 • 110 citations

Regulation of beta-cell glucose transporter gene expression.

1990 • 107 citations

Kallikrein-related mRNAs of the rat submaxillary gland: nucleotide sequences of four distinct types including tonin

1985 • 104 citations

Insulin secretory responses of a clonal cell line of simian virus 40-transformed B cells

1986 • 97 citations

Tissue-specific expression of glucokinase: identification of the gene product in liver and pancreatic islets.

1986 • 90 citations

Cloning and functional expression of a human pancreatic islet glucose-transporter cDNA.

1989 • 88 citations

Inhibition of Glucose Transport into Rat Islet Cells by Immunoglobulins from Patients with New-Onset Insulin-Dependent Diabetes Mellitus

1990 • 87 citations

Expression of the human insulin gene and cDNA in a heterologous mammalian system.

1983 • 77 citations

Polymorphic Human Glucose Transporter Gene (GLUT) is on Chromosome 1p31.3→p35

1987 • 74 citations

The glucose-phosphorylating capacity of liver as measured by three independent assays. Implications for the mechanism of hepatic glycogen synthesis.

1986 • 69 citations

Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis

1990 • 46 citations

Islet Cell Culture in Defined Serum-Free Medium*

1990 • 38 citations

Control of Glucose Metabolism in Pancreatic β-Cells by Glucokinase, Hexokinase and Phosphofructokinase: Model Study With Cell Lines Derived From β-Cells

1988 • 37 citations

A new clonal strain of rat pituitary tumour cells: a model for non-regulated secretion of prolactin

1984 • 35 citations

Alternative splicing of glucokinase mRNA in rat liver

1990 • 35 citations

Control of Glucose Phosphorylation and Glucose Usage in Clonal Insulinoma Cells

1988 • 26 citations