Insertion and amplification of foreign genes in the Lactococcus lactis subsp. lactis chromosome

Experiments With Gene Fusions

1984 • 2,487 citations

Improved Medium for Lactic Streptococci and Their Bacteriophages

1975 • 2,294 citations

Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies

1982 • 498 citations

Two plasmid-determined restriction and modification systems in Streptococcus lactis

1984 • 425 citations

Construction of a vector plasmid family and its use for molecular cloning in Streptococcus lactis

1988 • 413 citations

Construction of plasmid cloning vectors for lactic streptococci which also replicate in Bacillus subtilis and Escherichia coli

1984 • 382 citations

Efficient transformation of Neurospora crassa by utilizing hybrid plasmid DNA

1979 • 314 citations

Replacement of the Bacillus subtilis subtilisin structural gene with an In vitro-derived deletion mutation

1984 • 310 citations

Replacement and amplification of bacterial genes with sequences altered in vitro.

1983 • 181 citations

Insertional mutagenesis in Bacillus subtilis: mechanism and use in gene cloning

1982 • 139 citations

Mapping a cloned gene under sporulation control by inserttion of a drug resistance marker into the Bacillus subtilis chromosome

1980 • 130 citations

Isolation of transformation-deficient Streptococcus pneumoniae mutants defective in control of competence, using insertion-duplication mutagenesis with the erythromycin resistance determinant of pAM beta 1

1984 • 109 citations

Mechanism of integrating foreign DNA during transformation of Bacillus subtilis.

1978 • 108 citations

Molecular cloning–A laboratory manual. New York: Cold Spring Harbor Laboratory. 1982, 545 S., 42 $

1985 • 96 citations

Amplified DNA in Streptomyces fradiae

1983 • 95 citations

Stable gene amplification in the chromosome of Bacillus subtilis

1985 • 85 citations

Gene Amplification in Bacillus subtilis

1984 • 84 citations

Rapid cloning of specific DNA fragments of Streptococcus pneumoniae by vector integration into the chromosome followed by endonucleolytic excision

1981 • 78 citations

High-efficiency transformation of Streptococcus lactis protoplasts by plasmid DNA

1986 • 64 citations

A technique for integrating any DNA fragment into the chromosome of Escherichia coli

1984 • 60 citations

Lysogenic Strains of Lactic Acid Streptococci and Lytic Spectra of Their Temperate Bacteriophages

1982 • 48 citations

Conjugative transfer of the transposon Tn919to lactic acid bacteria

1985 • 48 citations

Protoplast transformation of group N streptococci with cryptic plasmids

1985 • 43 citations

Amplification of a chimeric plasmid carrying an erythromycin-resistance determinant introduced into the genome of Streptococcus pneumoniae

1983 • 43 citations

Modes of integration of heterologous plasmid DNA into the chromosome of Streptococcus pneumoniae

1985 • 41 citations

Integration of linear, heterologous DNA molecules into the Bacillus subtilis chromosome: mechanism and use in induction of predictable rearrangements

1985 • 40 citations

Genetic mapping of a linked cluster of ribosomal ribonucleic acid genes in Bacillus subtilis

1981 • 37 citations

Shotgun cloning inStreptococcus lactis

1987 • 37 citations

The Mechanism of Insertion of a Segment of Heterologous DNA into the Chromosome of Bacillus subtilis

1983 • 35 citations

Cloning and physical characterization of chromosomal conjugative elements in streptococci

1986 • 31 citations

Determination of the chromosomal locations of four Bacillus subtilis genes which code for a family of small, acid-soluble spore proteins

1986 • 23 citations

Amplification of the amyE-tmrB region on the chromosome in tunicamycin-resistant cells of Bacillus subtilis

1986 • 14 citations

Recombination efficiency is a quadratic function of the length of homology during plasmid transformation of Bacillus subtilis protoplasts and Escherichia coli competent cells.

1984 • 14 citations