High pressure effects on protein structure and function

Coupling of Local Folding to Site-Specific Binding of Proteins to DNA

1994 • 1,382 citations

The Control of Protein Stability and Association by Weak Interactions with Water: How Do Solvents Affect These Processes?

1993 • 1,076 citations

Proteins under pressure

1994 • 682 citations

Activation and reaction volumes in solution. 2

1989 • 565 citations

High Pressure Effects on Proteins and other Biomolecules

1982 • 540 citations

Activation and Reaction Volumes in Solution. 3

1998 • 524 citations

Pressure Stability of Proteins

1993 • 515 citations

THE COAGULATION OF ALBUMEN BY PRESSURE

1914 • 406 citations

The Theory of Pressure Effects on Enzymes

1981 • 343 citations

Crystal structure of hen egg-white lysozyme at a hydrostatic pressure of 1000 atmospheres

1987 • 330 citations

Adaptations to High Hydrostatic Pressure

1992 • 320 citations

Exploiting the effects of high hydrostatic pressure in biotechnological applications

1994 • 288 citations

Thermodynamics of unfolding

1987 • 252 citations

Ultrasonic Velocimetry of Biological Compounds

1991 • 230 citations

A γ-chain complex forms a functional receptor on cloned human lymphocytes with natural killer-like activity

1987 • 199 citations

Evidence for a molten globule-like transition state in protein folding from determination of activation volumes

1995 • 168 citations

High-Pressure NMR Spectroscopy of Proteins and Membranes

1994 • 167 citations

Molecular dynamics simulation of solvated protein at high pressure

1992 • 148 citations

Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy

1993 • 128 citations

Activation volumes in enzymic catalysis: their sources and modification by low-molecular-weight solutes.

1975 • 117 citations

Pressure effects on protein secondary structure and hydrogen deuterium exchange in chymotrypsinogen: a Fourier transform infrared spectroscopic study

1988 • 113 citations

High-resolution NMR study of the pressure-induced unfolding of lysozyme

1992 • 112 citations

Compactness of thermally and chemically denatured ribonuclease A as revealed by volume and compressibility

1995 • 110 citations

Arc Repressor will not Denature Under Pressure in the Absence of Water

1994 • 100 citations

Protein hydration changes during catalysis: a new mechanism of enzymic rate-enhancement and ion activation/inhibition of catalysis.

1975 • 92 citations

Phenomenological description of the association of protein subunits subjected to conformational drift. Effects of dilution and of hydrostatic pressure

1986 • 89 citations

Pressure Effects on Protein Flexibility Monomeric Proteins

1994 • 88 citations

Macromolecular binding equilibria in the lac repressor system: studies using high-pressure fluorescence spectroscopy

1990 • 81 citations

Thermodynamics of the association and the pressure dissociation of oligomeric proteins

1993 • 80 citations

Cold denaturation of a repressor-operator complex: the role of entropy in protein-DNA recognition.

1994 • 77 citations

Studies of polymer effects under pressure. Part 7. Pressure inactivation of .alpha.-chymotrypsin

1983 • 75 citations

Effect of pressure on the solubilities of benzene and alkylbenzenes in water

1989 • 74 citations

Heterogeneity in molecular recognition by restriction endonucleases: osmotic and hydrostatic pressure effects on BamHI, Pvu II, and EcoRV specificity.

1995 • 68 citations

Hydrostatic Pressure Reverses Osmotic Pressure Effects on the Specificity of EcoRI-DNA Interactions

1994 • 64 citations

Pressure denaturation of the bacteriophage P22 coat protein and its entropic stabilization in icosahedral shells

1994 • 61 citations

High Hydrostatic Pressure Induces the Dissociation of cpn60 Tetradecamers and Reveals a Plasticity of the Monomers

1995 • 59 citations

High-Pressure NMR Study of the Dissociation of Arc Repressor

1994 • 58 citations

Antagonistic effects of hydrostatic pressure and osmotic pressure on cytochrome P-450cam spin transition

1995 • 50 citations

High-pressure stopped-flow fluorometry at subzero temperatures: Application to kinetics of the binding of NADH to liver alcohol dehydrogenase

1987 • 49 citations

Cold Denaturation of an Icosahedral Virus. The Role of Entropy in Virus Assembly

1995 • 49 citations

Adiabatic compressibility of molten globules

1993 • 45 citations

Raman spectroscopic study of the changes in secondary structure of chymotrypsin: effect of pH and pressure on the salt bridge

1989 • 44 citations

Differences in Pressure Stability of the Three Components of Cowpea Mosaic Virus: Implications for Virus Assembly and Disassembly

1994 • 41 citations

Activation and reaction volumes in solution. 2 [Erratum to document cited in CA110(24):219738v]

1989 • 34 citations

Volume changes during enzyme reactions: indications of enzyme pulsation during fumarase catalysis

1988 • 34 citations

A reactor permitting injection and sampling for steady state studies of enzymatic reactions at high pressure: Tests with aspartate transcarbamylase

1990 • 31 citations

Slab gel electrophoresis of oligomeric proteins under high hydrostatic pressure

1987 • 29 citations

Structure and ligand binding properties of leucine 29(B10) mutants of human myoglobin.

1992 • 27 citations

The Role of Water in the Dissociation of Enolase, a Dimeric Enzyme

1993 • 27 citations

Electrophoresis at elevated hydrostatic pressure of the multiheme hydroxylamine oxidoreductase

1990 • 26 citations

Pressure tuning spectroscopy of the low-frequency Raman spectrum of liquid amides

1993 • 25 citations

Cryobaroenzymic studies as a tool for investigating activated complexes: creatine kinase.ADP.Mg.nitrate.creatine as a model.

1985 • 25 citations

An infrared study of ²H‐bond variation in myoglobin revealed by high pressure

1992 • 22 citations

Pressure Effects on Structure and Activity of Cholinesterase

1995 • 10 citations

Determination of reaction volumes and polymer distribution characteristics of tobacco mosaic virus coat protein

1987 • 9 citations

Pressure Effects and Thermal Stability of Myosin Rods and Rod Minifilaments: Fluorescence and Circular Dichroism Studies

1994 • 8 citations