Sino-atrial and atrial electrogenesis

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1960 • 10,428 citations

The effect of sodium ions on the electrical activity of the giant axon of the squid

1949 • 3,479 citations

Electric current flow in excitable cells

1976 • 1,353 citations

Electrophysiology of the Heart.

1960 • 1,295 citations

Atrial fibrillation as a self-sustaining arrhythmia independent of focal discharge

1959 • 889 citations

The Mechanism and Graphic Registration of the Heart Beat.

1925 • 822 citations

Electrogenic sodium pump in nerve and muscle cells.

1972 • 787 citations

The effect of the cardiac membrane potential on the rapid availability of the sodium‐carrying system

1955 • 763 citations

On dynamic equilibrium in the heart

1913 • 732 citations

Circus movement in rabbit atrial muscle as a mechanism of trachycardia.

1973 • 689 citations

The Form and Nature of the Muscular Connections between the Primary Divisions of the Vertebrate Heart.

1907 • 605 citations

Circus movement in rabbit atrial muscle as a mechanism of tachycardia. II. The role of nonuniform recovery of excitability in the occurrence of unidirectional block, as studied with multiple microelectrodes.

1976 • 484 citations

The Role of Premature Beats in the Initiation and the Termination of Supraventricular Tachycardia in the Wolff-Parkinson-White Syndrome

1967 • 474 citations

Cardiac resting and action potentials recorded with an intracellular electrode

1951 • 474 citations

Premature Atrial Stimulation as a Key to the Understanding of Sinoatrial Conduction in Man

1973 • 454 citations

Circus Movement in Rabbit Atrial Muscle as a Mechanism of Tachycardia

1973 • 453 citations

Electric Current Flow in Excitable Cells.

1975 • 435 citations

On the electrogenic sodium pump in mammalian non‐myelinated nerve fibres and its activation by various external cations

1968 • 430 citations

Evaluation of Sino-atrial Node Function in Man by Overdrive Suppression

1971 • 416 citations

The connecting pathways between the sinus node and A-V node and between the right and the left atrium in the human heart

1963 • 408 citations

The Effects of Cycle Length on Cardiac Refractory Periods in Man

1974 • 388 citations

The Sick Sinus Syndrome

1973 • 362 citations

VAGAL AND SYMPATHETIC EFFECTS ON THE PACEMAKER FIBERS IN THE SINUS VENOSUS OF THE HEART

1956 • 359 citations

Multiple effects of calcium antagonists on plateau currents in cardiac Purkinje fibers.

1975 • 320 citations

Immediate Effects of Intravenous Verapamil in Cardiac Arrhythmias

1972 • 311 citations

Nonuniform Distribution of Vagal Effects on the Atrial Refractory Period

1958 • 310 citations

Effect of intracellular injection of calcium and strontium on cell communication in heart.

1975 • 307 citations

THE ULTRASTRUCTURE OF THE CAT MYOCARDIUM

1969 • 306 citations

Effect of Verapamil on the Sinoatrial and Atrioventricular Nodes of the Rabbit and the Mechanism by Which it Arrests Reentrant Atrioventricular Nodal Tachycardia

1974 • 285 citations

Heart: Excitation and Contraction

1971 • 277 citations

LANTHANUM IN HEART CELL CULTURE

1972 • 270 citations

The Mechanism of Supraventricular Tachycardia

1970 • 254 citations

Anatomy of the human sinus node

1961 • 248 citations

Tachycardia-bradycardia syndrome (so-called “sick sinus syndrome”)

1973 • 247 citations

Zum Mechanismus der Membranwirkung des Acetylcholin an der Herzmuskelfaser

1958 • 247 citations

Electrogenic Suppression of Automaticity in Sheep and Dog Purkinje Fibers

1970 • 244 citations

On the Innervation of the Heart, with especial reference to the Heart of the Tortoise

1883 • 233 citations

Membrane currents in the rabbit sinoatrial node cell as studied by the double microelectrode method

1976 • 230 citations

Comparative Ultrastructure of the Sinus Node in Man and Dog

1966 • 220 citations

On the mechanism of the negative inotropic effect of acetylcholine

1976 • 218 citations

Effect of Several Cations on Transmembrane Potentials of Cardiac Muscle

1956 • 211 citations

THE INTER-AURICULAR TIME INTERVAL

1916 • 208 citations

Electrical Transmission at the Nexus between Smooth Muscle Cells

1968 • 203 citations

Electrophysiologic evaluation of sinus node function in patients with sinus node dysfunction.

1976 • 202 citations

Cardiac Cellular Potentials: Effect of Vagal Stimulation and Acetylcholine

1953 • 202 citations

On the negative inotropic effect in the cat's auricle

1953 • 202 citations

Electrophysiological evidence for specialized fiber types in rabbit atrium

1959 • 200 citations

Verapamil in the treatment of paroxysmal supraventricular tachycardia

1974 • 195 citations

Electrophysiologic properties and response to pharmacologic agents of fibers from diseased human atria.

1976 • 194 citations

Factors Controlling Pacemaker Action in Cells of the Sinoatrial Node

1965 • 185 citations

Spread of Excitation from the Sinus Node

1965 • 172 citations

Intracellular sodium activity and the sodium pump in snail neurones

1972 • 170 citations

Electrical Phenomena in the Heart

1972 • 162 citations

The Conduction System of the Heart. Structure, Function and Clinical Implications.

1976 • 161 citations

Two Components of the Cardiac Action Potential

1969 • 154 citations

The electrophysiologic demonstration of atrial ectopic tachycardia in man

1973 • 149 citations

Electron microscopic and electrophysiologic study of the pacemaker in the sino-atrial node of the rabbit heart

1963 • 143 citations

Electrophysiological Properties of Cardiac Muscle in the Anterior Mitral Valve Leaflet and the Adjacent Atrium in the Dog

1973 • 135 citations

Excitation Sequences of the Atrial Septum and the AV Node in Isolated Hearts of the Dog and Rabbit

1971 • 134 citations

Specialized Conducting Fibers in the Interatrial Band

1966 • 134 citations

Production of Membrane Potential Changes in the Frog's Heart by Inhibitory Nerve Impulses

1955 • 132 citations

Electrophysiological Study of Human Heart Muscle

1962 • 131 citations

Electrophysiologic Studies in Patients with Persistent Atrial Tachycardia

1974 • 126 citations

THE HUMAN PACEMAKER AND ITS PATHOLOGY

1960 • 122 citations

Anatomy of the sinus node of the dog

1962 • 119 citations

Specialized tissues and preferential conduction in the atria of the heart

1971 • 118 citations

Electrophysiological Properties of the Rabbit Sinoatrial Perinodal Fibers

1972 • 117 citations

Sino-Atrial Reciprocation in the Isolated Rabbit Heart

1968 • 115 citations

Potassium ions and electrical activity of specialized cardiac fibers

1960 • 115 citations

Membrane currents underlying delayed rectification and pace‐maker activity in frog atrial muscle

1969 • 113 citations

A COMPARISON OF THE CONDUCTION VELOCITY IN CARDIAC TISSUES OF VARIOUS MAMMALS

1959 • 112 citations

Ultramicroelectrode recording from the cardiac pacemaker.

1955 • 112 citations

Electrophysiologic Properties of Isolated Preparations of Human Atrial Myocardium

1972 • 111 citations

The Spread of Sinus Activation During Potassium Administration

1965 • 110 citations

The initiation of the heart beat.

1966 • 109 citations

Termination of Reciprocating Tachycardia by Atrial Stimulation

1967 • 108 citations

The mechanism of auricular paroxysmal tachycardia

1943 • 107 citations

Der Mechanismus der automatischen rhythmischen Impulsbildung der Herzmuskelfaser

1958 • 106 citations

CHANGES IN MEMBRANE CHARACTERISTICS OF HEART MUSCLE DURING INHIBITION

1956 • 105 citations

Comparative ultrastructure of cellular junctions in working myocardium and the conduction system under normal and pathologic conditions

1971 • 104 citations

Anatomy of the Cardiac Conduction System in the Rabbit

1967 • 97 citations

Electrotonic spread in the sinoatrial node of the rabbit heart

1973 • 95 citations

Atrial parasystole with interpolation Observations on prolonged sinoatrial conduction

1962 • 91 citations

The membrane resting and action potentials of the cat auricle

1953 • 90 citations

Effect of an Early Atrial Premature Beat on Activity of the Sinoatrial Node and Atrial Rhythm in the Rabbit

1971 • 90 citations

P waves during ectopic atrial rhythms in man: a study utilizing atrial pacing with fixed electrodes.

1975 • 90 citations

Intercellular coupling in the atrioventricular node and other tissues of the rabbit heart.

1976 • 89 citations

Ultrastructure of the Mammalian Heart

1973 • 87 citations

Sinus nodal echoes

1973 • 82 citations

Analysis of secondary pauses following termination of rapid atrial pacing in man.

1976 • 79 citations

Conversion of Supraventricular Tachycardias with Atrial Stimulation

1968 • 78 citations

Measurement of Sinoatrial Conduction Time by Premature Atrial Stimulation in the Rabbit

1974 • 76 citations

Sinus Node Reentry

1973 • 73 citations

The influence of sympathetic stimulation on transmembrane potentials in the S-A node.

1968 • 73 citations

Reconstruction of the human sinoatrial node

1967 • 70 citations

Effect of Tetrodotoxin on the Pacemaker Action Potential of the Sinus Node

1966 • 68 citations

Drug alteration of transmembrane potentials in atrial pacemaker cells.

1956 • 68 citations

Electron Microscope Observations of the S.A and A.V Nodes and Purkinje Fibers of the Rabbit

1962 • 67 citations

Electrogenic sodium pump in rabbit sinoatrial node cell

1974 • 65 citations

Interactions of K, Na, and vagal stimulation in the S-A node of the rabbit

1967 • 64 citations

THE EFFECT OF VAGUS INHIBITION ON THE OUTPUT OF POTASSIUM FROM THE HEART

1908 • 63 citations

Actions of Diphenylhydantoin on the Electrical Properties of Isolated Rabbit and Canine Atria

1968 • 62 citations

Analysis of pace‐maker and repolarization currents in frog atrial muscle.

1976 • 61 citations

Effect of Calcium on the Membrane Potentials of Single Pacemaker Fibres and Atrial Fibres in Isolated Rabbit Atria

1964 • 61 citations

Passive electrical properties of atrial fibers of the rabbit heart

1973 • 60 citations

Shifts in Pacemaker Dominance within the Sinoatrial Region of Cat and Rabbit Hearts Resulting from Increase of Extracellular Potassium

1970 • 60 citations

Brief Reviews : The Sinus Node as a Servomechanism

1973 • 60 citations

ULTRASTRUCTURE OF THE INNERVATION OF THE MAMMALIAN HEART

1973 • 58 citations

Interaction between Na, Ca, Mg, and vagal stimulation in the S-A node of the rabbit

1967 • 58 citations

Identification of the pace‐maker current in frog atrium.

1976 • 57 citations

Acetylcholine and potassium movements in rabbit auricles

1959 • 57 citations

Activation of the electrogenic sodium pump in guinea‐pig auricles by internal sodium ions

1972 • 56 citations

On The Electrotonic Spread in Cardiac Muscle of the Mouse

1966 • 54 citations

Contribution of an electrogenic sodium pump to the membrane potential in rabbit sinoatrial node cells

1975 • 53 citations

Some observations concerning the mode of action of acetylcholine in isolated rabbit atria

1958 • 52 citations

Eelctrophysiologic and ultrastructural characteristics of the canine tricuspid valve

1976 • 51 citations

On the Action of Muscarin upon the Heart, and on the Electrical Changes in the non‐beating Cardiac Muscle brought about by Stimulation of the Inhibitory and Augmentor Nerves

1887 • 51 citations

EFFECTS OF Na+ AND K+ ON THE RESTING MEMBRANE POTENTIAL OF THE RABBIT SINOATRIAL NODE CELL

1975 • 50 citations

Evidence for the existence of a rapid sodium channel in the membrane of rabbit sinoatrial cells

1975 • 48 citations

Pacemaker potentials. The excitation of isolated rabbit auricles by acetylcholine at low temperatures

1956 • 48 citations

Hemmende und ?erregende? Wirkungen des Acetylcholin am Warmbl�terherzen. Zur Frage der spontanen Erregungsbildung

1958 • 48 citations

Adrenergic control of cardiac pacemaker currents

1975 • 44 citations

An effect of the electrogenic sodium pump on the membrane potential in beating guinea-pig atria

1973 • 44 citations

Atrial Ultrastructure in Patients with Fixed Intra-atrial Block

1974 • 43 citations

The effect of changes in extracellular potassium concentration on the intracellular potentials of isolated rabbit atria

1959 • 43 citations

Familial sinoatrial node dysfunction. Increased vagal tone a possible aetiology.

1976 • 40 citations

THE EFFECT OF SODIUM ION ON THE INITIAL PHASE OF THE SINOATRIAL PACEMAKER ACTION POTENTIALS IN RABBITS

1974 • 39 citations

A comparative histochemical and electron microscopic study of the surface coatings of cardiac muscle cells

1970 • 39 citations

The Fine Structure of the Atrial and Atrioventricular (AV) Junctional Specialized Tissues of the Rabbit Heart

1978 • 38 citations

Effects of acetylcholine on membrane currents in frog artrial muscle.

1975 • 34 citations

THE ULTRASTRUCTURE OF VENTRICULAR AND ATRIAL MYOCARDIUM

1973 • 33 citations

EFFECTS OF CALCIUM ION ON THE RISING PHASE OF THE ACTION POTENTIAL IN RABBIT SINOATRIAL NODE CELLS

1976 • 31 citations

Influence of sodium ions on the membrane potential of the sino‐atrial node in response to sympathetic nerve stimulation

1968 • 30 citations

Myocardial cell diameters in primate hearts

1972 • 27 citations

Pharmacology of Cardiac Function

1964 • 26 citations

Role of chloride ions in cardiac action and pacemaker potentials

1963 • 26 citations

Effects of Na+ and K+ on the resting membrane potential of the rabbit sinoatrial node cell

1975 • 25 citations

Membrane ionic conductances during rest and activity in guinea pig atrial muscle

1967 • 25 citations

The Sinoatrial Node and its Connections with the Atrial Tissues

1978 • 25 citations

Direct and Indirect Techniques in the Evaluation of Sinus Node Function

1978 • 23 citations

Pacemaker Current in Frog Atrium

1972 • 19 citations

Effects of acetylcholine on mechanical and electrical properties of isolated rabbit auricle: their relationship to the genesis of arrhythmias.

1954 • 15 citations

Electrophysiologic testing in patients with sinus pauses and/or sinoatrial exit block.

1978 • 14 citations

Acetylcholine-induced reversal of canine and feline atrial myocardial depression during stretch, cardiac failure, and drug toxicity.

1975 • 11 citations

Failure to propagate a Lactic Dehydrogenase-elevating Agent from Mice Tumours in Mice Embryo Cultures

1964 • 10 citations

Sodium pump: Its importance to intercellular communication in heart fibres

1976 • 6 citations

Membrane Lipids and Cardiac Electrogenesis

1972 • 6 citations

The Membrane Capacitance of Heart Cells

1972 • 5 citations

Effect of hypoxia on the vascular response to isoproterenol and norepinephrine

1969 • 4 citations