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Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation

1999 • 2,990 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Systematic variation in gene expression patterns in human cancer cell lines

2000 • 2,119 citations

The Transcriptional Program in the Response of Human Fibroblasts to Serum

1999 • 1,994 citations

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

Genomic analysis of metastasis reveals an essential role for RhoC

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Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression.

1990 • 771 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Selection of Invasive and Metastatic Subpopulations from a Human Lung Adenocarcinoma Cell Line

1997 • 415 citations

Pieces of the puzzle: expressed sequence tags and the catalog of human genes

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Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]

1988 • 311 citations

Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas

1998 • 278 citations

The α3β1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (mmp-9) activity

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Altered levels of laminin receptor mRNA in various human carcinoma cells that have different abilities to bind laminin.

1986 • 261 citations

Profiling Expression Patterns and Isolating Differentially Expressed Genes by cDNA Microarray System with Colorimetry Detection

1998 • 226 citations

Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region.

1999 • 218 citations

Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice.

1993 • 201 citations

High expression level of alpha 6 integrin in human breast carcinoma is correlated with reduced survival.

1995 • 194 citations

Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44.

1991 • 187 citations

Expression profiling in cancer using cDNA microarrays

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Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment.

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Cloning and expression of the tumor-associated antigen L6.

1992 • 130 citations

Metastasis-associated Mts1 (S100A4) Protein Modulates Protein Kinase C Phosphorylation of the Heavy Chain of Nonmuscle Myosin

1998 • 130 citations

Expression of calcyclin in human melanoma cell lines correlates with metastatic behavior in nude mice.

1992 • 128 citations

Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer

1998 • 113 citations

Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential.

1992 • 112 citations

Cooperation Between Transcription Factor AP-1 and NF-kappa B in the Induction of Interleukin-8 in Human Pancreatic Adenocarcinoma Cells by Hypoxia

1999 • 100 citations

Expression of the Axl Receptor Tyrosine Kinase in Human Thyroid Carcinoma

1999 • 80 citations

Profiling the Downstream Genes of Tumor Suppressor PTEN in Lung Cancer Cells by Complementary DNA Microarray

2000 • 75 citations

Elevation of urokinase-type plasminogen activator and its receptor densities as new predictors of disease progression and prognosis in men with prostate cancer.

1999 • 73 citations

Expression of nm23 H-1 RNA levels in human gastric cancer tissues. A negative correlation with nodal metastasis

1994 • 68 citations

Urokinase and the Urokinase Receptor: Association With In Vitro Invasiveness of Human Bladder Cancer Cell Lines

1997 • 53 citations

A Receptor Tyrosine Kinase, UFO/Axl, and Other Genes Isolated by a Modified Differential Display PCR Are Overexpressed in Metastatic Prostatic Carcinoma Cell Line DU145

1999 • 52 citations

Tumour vascularity is a significant prognostic factor for cervix carcinoma treated with radiotherapy: Independence from tumour radiosensitivity

1999 • 50 citations

A novelin vitro assay system for transendothelial tumor cell invasion: significance of E-selectin and α3 integrin in the transendothelial invasion by HT1080 fibrosarcoma cells

1994 • 40 citations

Soluble CD44 Isoforms in Serum as Potential Markers of Metastatic Gastric Carcinoma

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[Detection of hL6-mRNA: new possibilities in serologic tumor diagnosis of colorectal carcinomas].

1998 • 6 citations