The Control of Neuron Number

Ontogeny and Phylogeny

1977 • 3,887 citations

CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

1942 • 3,059 citations

THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN 1

1948 • 1,810 citations

Genetic control of programmed cell death in the nematode C. elegans

1986 • 1,790 citations

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

1982 • 1,635 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

A common progenitor for neurons and glia persists in rat retina late in development

1987 • 1,395 citations

CELL DEATHS IN NORMAL VERTEBRATE ONTOGENY

1951 • 1,194 citations

Optic Nerve Damage in Human Glaucoma

1982 • 1,167 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

A major developmental transition in early xenopus embryos: II. control of the onset of transcription

1982 • 1,065 citations

An autoradiographic analysis of histogenesis in the mouse cerebellum

1961 • 1,008 citations

The Mammalian Radiations: An Analysis of Trends in Evolution, Adaptation, and Behavior

1981 • 772 citations

EGG-LAYING DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

1983 • 730 citations

Relative brain size and basal metabolic rate in terrestrial vertebrates

1981 • 721 citations

Neurogenesis and neuron regeneration in the olfactory system of mammals. II. Degeneration and reconstitution of the olfactory sensory neurons after axotomy

1979 • 515 citations

Amacrine cells, bipolar cells and ganglion cells of the cat retina: A Golgi study

1981 • 512 citations

Limits of Neurogenesis in Primates

1985 • 486 citations

The effects of early hypo- and hyperthyroidism on the development of rat cerebellar cortex. I. Cell proliferation and differentiation

1972 • 456 citations

Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions

1986 • 456 citations

Relation of Gestation Time to Brain Weight for Placental Mammals: Implications for the Theory of Vertebrate Growth

1974 • 446 citations

The human brain in figures and tables : a quantitative handbook

1968 • 440 citations

Anatomical, Physiological and biochemical studies of the cerebellum fromreelermutant mouse

1977 • 398 citations

Mutations Affecting Programmed Cell Deaths in the Nematode Caenorhabditis elegans s

1983 • 389 citations

NEURONAL DEATH AS A REGULATIVE MECHANISM IN THE CONTROL OF CELL NUMBER IN THE NERVOUS SYSTEM

1973 • 364 citations

Local Differences in the Amount of Early Cell Death in Neocortex Predict Adult Local Specializations

1983 • 279 citations

Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death

1986 • 254 citations

Overproduction and Elimination of Retinal Axons in the Fetal Rhesus Monkey

1983 • 246 citations

Cell Lineage Analysis by Intracellular Injection of a Tracer Enzyme

1978 • 233 citations

VULNERABILITY OF DEVELOPING BRAIN AND BEHAVIOUR

1974 • 233 citations

Motor localization and the effects of nerve injury on the ventral horn cells of the spinal cord.

1946 • 229 citations

The growth and organization of the optic nerve and tract in juvenile and adult goldfish

1981 • 212 citations

The origin and development of the visceral in the spinal cord of the chick embryo

1950 • 211 citations

Growth cones, dying axons, and developmental fluctuations in the fiber population of the cat's optic nerve

1986 • 207 citations

The development of the isthmo-optic tract in the chick, with special reference to the occurrence and correction of developmental errors in the location and connections of isthmo-optic neurons

1976 • 204 citations

Cell death of motoneurons in the chick embryo spinal cord. IX. The loss of motoneurons following removal of afferent inputs

1984 • 202 citations

Structure and Development of Neuronal Connections in Isogenic Organisms: Variations and Similarities in the Optic System of Daphnia magna

1973 • 202 citations

Number and distribution of neurons in leech segmental ganglia

1980 • 193 citations

Regulation of tyrosine hydroxylase-containing amacrine cell number in larval frog retina

1986 • 180 citations

Cyclic AMP as a mitogenic signal for cultured rat Schwann cells

1978 • 177 citations

The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat

1986 • 175 citations

Retinal Ganglion Cells: Properties, Types, Genera, Pathways and Trans-Species Comparisons; pp. 121–131

1983 • 167 citations

Cell number and cell density in the cerebellar cortex of man and some other mammals

1975 • 164 citations

Changes in the numbers of optic nerve fibers during late prenatal and postnatal development in the albino rat

1985 • 162 citations

Evolution of the nervous system: Role of ontogenetic mechanisms in the evolution of matching populations

1978 • 157 citations

Development of the Retinotectal Projection in the Chicken

1980 • 154 citations

Cell degeneration in the developing optic lobes of the sine oculis and small-optic-lobes mutants of Drosophila melanogaster

1984 • 153 citations

The development of the primary sensory system in Xenopus laevis (Daudin).

1957 • 150 citations

The control of glial populations in brain: Changes in astrocyte mitogenic and morphogenic factors in response to injury

1985 • 149 citations

Ganglion cell death within the developing retina: A regulatory role for retinal dendrites?

1982 • 136 citations

Origin of the Retina from Both Sides of the Embryonic Brain: A Contribution to the Problem of Crossing at the Optic Chiasma

1978 • 136 citations

Direct correlation between Purkinje and granule cell number in the cerebella of lurcher chimeras and wild-type mice

1983 • 135 citations

Relation of animal size to convergence, divergence, and neuronal number in peripheral sympathetic pathways

1986 • 133 citations

Site of pcd gene action and Purkinje cell mosaicism in cerebella of chimaeric mice

1977 • 133 citations

Role of staggerer gene in determining cell number in cerebellar cortex. I. Granule cell death is an indirect consequence of staggerer gene action

1983 • 132 citations

THE GENETIC CONTROL OF CELL LINEAGE DURING NEMATODE DEVELOPMENT

1984 • 130 citations

Genetic Relationships Between Inbred Strains of Mice

1972 • 128 citations

Effects of p-chlorophenylalanine on time of neuronal origin during embryo-genesis in the rat

1976 • 125 citations

Programmed cell death in the nervous system of an adult insect

1983 • 123 citations

Motor and Sensory Hyperplasia following Limb-Bud Transplantations in Chick Embryos

1939 • 123 citations

Evidence for discrete cell kinetic subpopulations in mouse epidermis based on mathematical analysis

1982 • 117 citations

Stimulation of the Proliferation of Cortical Neurons by Prenatal Treatment with Growth Hormone

1966 • 110 citations

Numerical matching during cerebellar development: quantitative analysis of granule cell death in staggerer mouse chimeras

1987 • 107 citations

Cerebellar Purkinje cells are descended from a small number of progenitors committed during early development: quantitative analysis of lurcher chimeric mice

1982 • 100 citations

Regressive Events in Brain Development and Scenarios for Vertebrate Brain Evolution

1987 • 98 citations

THE ANATOMICAL AND PHYSIOLOGICAL EFFECTS OF PRENATALLY ADMINISTERED SOMATOTROPHIN ON CEREBRAL DEVELOPMENT IN RATS

1961 • 97 citations

Stepwise commitment of blast cell fates during the positional specification of the O and P cell lines in the leech embryo

1984 • 96 citations

Cell death of lumbosacral motoneurons in chick, quail, and chick-quail chimera embryos: a test of the quantitative matching hypothesis of neuronal cell death

1986 • 91 citations

The development of the optic lobes in the frog. I. The effects of unilateral enucleation in embryonic stages

1953 • 87 citations

OPTIC NERVE FIBRE COUNTS AND RETINAL GANGLION CELL COUNTS DURING DEVELOPMENT OF XENOPUS LAEVIS (DAUDIN)

1971 • 77 citations

Structural brain mutant of Drosophila melanogaster with reduced cell number in the medulla cortex and with normal optomotor yaw response

1981 • 76 citations

A study of monozygous quadruplet armadillos in relation to mammalian inheritance.

1968 • 71 citations

The development of facial motoneurones in the mouse — neuronal death and the innervation of the facial muscles

1983 • 67 citations

Neuronal death and the development of the pontine nuclei and inferior olive in the chick

1979 • 67 citations

The development of lateral motor column cells in the lumbo‐sacral cord in Rana pipiens I. normal development and development following unilateral limb ablation

1955 • 67 citations

The factors controlling the development of the dorsal root ganglia and ventral horn in Xenopus laevis (Daud.).

1958 • 66 citations

The genetic organization of neuron number in ammon's horns of house mice

1976 • 62 citations

Generation of chick skeletal muscle cells in groups of 16 from stem cells

1985 • 61 citations

Grafting of additional periphery reduces embryonic loss of neurons

1979 • 61 citations

Binocular interaction in the fetal cat regulates the size of the ganglion cell population

1984 • 59 citations

Quantitative Analysis of Evolution of the Brain in Mammals

1961 • 57 citations

The quantitative investigation of the vertebrate brain and the applicability of allometric formulae to its study

1948 • 54 citations

Cell degeneration during normal ontogenesis of the rabbit brain.

1955 • 53 citations

Relative Brain Size and Metabolism in Birds

1985 • 51 citations

Role of staggerer gene in determining cell number in cerebellar cortex. II. Granule cell death and persistence of the external granule cell layer in young mouse chimeras

1984 • 51 citations

SCHWANN CELL MULTIPLICATION IN TREMBLER MICE

1981 • 50 citations

Neuron Duplications and Deletions in Locust Clones and Clutches

1977 • 50 citations

Influences of thyroxine on cell proliferation in the retina of the clawed frog at different ages

1979 • 47 citations

Constancy and Uniqueness in a Large Population of Small Interneurons

1976 • 46 citations

CEREBRALISATION UND ONTOGENESEMODUS BEI EUTHERIEN

1966 • 45 citations

Cell lineage relationships in the development of the mammalian CNS

1984 • 45 citations

Quantitative studies of superior cervical sympathetic ganglia in a variety of primates including man. I. The ratio of preganglionic fibers to ganglionic neurons

1968 • 45 citations

Segmental differentiation in the leech nervous system: The genesis of cell number in the segmental ganglia of haemopis marmorata

1986 • 44 citations

Cell lineage relationships in the development of the mammalian CNS: Role of cell lineage in control of cerebellar Purkinje cell number

1986 • 41 citations

The postnatal reduction of the uncrossed projection from the nasal retina in the cat

1984 • 40 citations

Cell lineage dependent and independent control of Purkinje cell number in the mammalian CNS: Further quantitative studies of lurcher chimeric mice

1986 • 38 citations

The mesencephalic V nucleus in anurans. I. Normal development in rana pipiens

1955 • 36 citations

Mosaic Evolution in the Primate Brain: Differences and Similarities in the Hominoid Thalamus

1982 • 35 citations

The developmental morphology of Torpedo marmorata: Electric lobe‐electromotoneuron proliferation and cell death

1982 • 34 citations

Age-dependent changes in myogenic precursor cell compartment sizes *1Evidence for the existence of a stem cell

1984 • 33 citations

Galathea report : scientific results of the Danish Deep-Sea Expedition Round the World 1950-52

1959 • 32 citations

Growth Hormone Administration during Pregnancy : a Behavioural Difference in Offspring Rats

1965 • 32 citations

Development of the lateral line system in Xenopus laevis : II Cell multiplication and organ formation in the supraorbital system

1983 • 31 citations

Cell death during gangliogenesis in the leech: bipolar cells appear and then degenerate in all ganglia

1987 • 30 citations

Quantitative cellular changes during postnatal development of the rat dorsal lateral geniculate nucleus

1986 • 29 citations

Peripheral control of midbrain mitotic activity in the frog

1982 • 28 citations

Analysis of the myogenic lineage in chick embryos

1983 • 25 citations

Influence of the environment on number of vertebrae in teleostean fishes.

1950 • 22 citations

Effect of Tetraploidy on Learning and Retention in the Salamander

1957 • 22 citations

Chapter 11 Early Organization of The Central Nervous System: Form and Pattern

1980 • 21 citations

Functional organization of the cat's visual cortex after prenatal interruption of binocular interactions.

1985 • 21 citations

Increased number of locus ceruleus noradrenergic neurons in the convulsive mutant quaking mouse

1985 • 20 citations

Le poids encéphalique en fonction du poids corporel entre individus d'une même espèce

1907 • 18 citations

Analysis of spatial constancy of oculomotor neurons in the crayfish

1976 • 16 citations

Growth and death of cells of the mesencephalic fifth nucleus in Xenopus laevis larvae

1985 • 16 citations

The limits of hereditary control in armadillo quadruplets: A study of blastogenic variation

1911 • 14 citations

Chapter 3 Roles of Cell Lineage in the Developing Mammalian Brain

1987 • 13 citations

The nuclear anatomy of the diencephalon of Sorex cinereus

1953 • 13 citations

Über einen Fall von Mikroencephalie ohne geistigen Defekt

1932 • 12 citations

Structural Evidence in the Brain for a Theory of the Evolution of Behavior

1960 • 12 citations

Clonal Attenuation In Chick Embryo Fibroblasts Experimental Data, A Model and Computer Simulations

1985 • 11 citations

Brain‐weights of animals with special reference to the weight of the brain in the Macaque monkey

1903 • 9 citations

Evidence for a myogenic stem cell

1984 • 1 citations