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Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.

Data up to Jan 2025

Published2002
Citations354
References38

Total Citations Per Year

Abstract

References (38)

Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

2001 • 2,558 citations

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.

1996 • 1,747 citations

Hypoxia-inducible expression of tumor-associated carbonic anhydrases.

2000 • 1,246 citations

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma.

1996 • 1,183 citations

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

1997 • 1,057 citations

HUMAN CARBONIC ANHYDRASES AND CARBONIC ANHYDRASE DEFICIENCIES

1995 • 809 citations

Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer

2001 • 655 citations

Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer.

2001 • 597 citations

Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix.

2001 • 456 citations

Prognostic Significance of a Novel Hypoxia-Regulated Marker, Carbonic Anhydrase IX, in Invasive Breast Carcinoma

2001 • 425 citations

Tumor Hypoxia Has Independent Predictor Impact Only in Patients With Node-Negative Cervix Cancer

2002 • 366 citations

Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer.

2001 • 338 citations

Microenvironment-induced cancer metastasis

2000 • 335 citations

Pimonidazole: A Novel Hypoxia Marker for Complementary Study of Tumor Hypoxia and Cell Proliferation in Cervical Carcinoma

1998 • 320 citations

Transcriptional Response to Hypoxia in Human Tumors

2001 • 300 citations

Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver

1995 • 296 citations

A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy

2000 • 278 citations

Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density.

2001 • 254 citations

Monoclonal antibody PAL-E specific for endothelium.

1985 • 251 citations

Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.

1998 • 244 citations

Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer.

2001 • 205 citations

Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays

1997 • 201 citations

Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy.

2001 • 199 citations

Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids

1995 • 197 citations

Detection of hypoxia in human squamous cell carcinoma by EF5 binding.

2000 • 188 citations

ARCON: experience in 215 patients with advanced head-and-neck cancer

2002 • 183 citations

The relationship between tumor oxygenation and cell proliferation in human soft tissue sarcomas

1996 • 147 citations

Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: a quantitative multi-parameter analysis

2000 • 126 citations

Cancer vascularization: implications in radiotherapy?

2000 • 103 citations

Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas

2000 • 93 citations

Changes in tumor hypoxia measured with a double hypoxic marker technique

2000 • 91 citations

Hypoxia-inducible factor-1alpha is an intrinsic marker for hypoxia in cervical cancer xenografts.

2001 • 88 citations

Application of an Image Analysis System to the Quantitation of Tumor Perfusion and Vascularity in Human Glioma Xenografts

1995 • 79 citations

Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia

2000 • 69 citations

Longevity of Pimonidazole Adducts in Spontaneous Canine Tumors as an Estimate of Hypoxic Cell Lifetime

1997 • 65 citations

Intratumoral microvessel density predicts local treatment failure of radically irradiated squamous cell cancer of the oropharynx

2000 • 56 citations

A Study of Biomarkers in Cervical Carcinoma and Clinical Correlation of the Novel Biomarker MN

1996 • 46 citations

Low Vascular Density Indicates Poor Response to Radiotherapy in Small Glottic Carcinomas

1996 • 15 citations

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