Immunoglobulin E–dependent Active Fatal Anaphylaxis in Mast Cell–deficient Mice

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Active anaphylaxis in IgE-deficient mice

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Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

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Differences in the expression of the cardiopulmonary alterations associated with anti-immunoglobulin E-induced or active anaphylaxis in mast cell-deficient and normal mice. Mast cells are not required for the cardiopulmonary changes associated with certain fatal anaphylactic responses.

1991 • 53 citations

Occurrence of disseminated Intravascular coagulation (DIC) in active systemic anaphylaxis: role of platelet-activating factor

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Mast cells contribute to the changes in heart rate, but not hypotension or death, associated with active anaphylaxis in mice.

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1990 • 26 citations

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Fc epsilon RI mediates IgE-binding to human epidermal Langerhans cells.

1993 • 5 citations