Effects of Octreotide Treatment on the Proliferation and Apoptotic Index of GH-Secreting Pituitary Adenomas

Monoclonal antibodies against recombinant parts of the Ki‐67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave‐processed formalin‐fixed paraffin sections

1992 • 1,484 citations

Molecular Biology of Somatostatin Receptors*

1995 • 636 citations

Oncological applications of somatostatin analogues.

1988 • 494 citations

Molecular pharmacology of somatostatin receptor subtypes

1997 • 411 citations

Long-Term Treatment of Acromegaly with the Somatostatin Analogue SMS 201–995

1985 • 396 citations

The somatostatin receptor family

1995 • 356 citations

Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).

1994 • 348 citations

Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.

1994 • 329 citations

Octreotide Treatment of Acromegaly

1992 • 270 citations

Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3.

1996 • 260 citations

Histopathological Evaluation of Apoptosis in Cancer

1998 • 245 citations

Long-term Treatment of 189 Acromegalic Patients With the Somatostatin Analog Octreotide

1991 • 234 citations

Somatostatin receptors in human cancer: Incidence, characteristics, functional correlates and clinical implications

1992 • 224 citations

THE BIOLOGY OF CELL DEATH IN TUMOURS

1973 • 222 citations

The Growth Hormone Responses to Octreotide in Acromegaly Correlate with Adenoma Somatostatin Receptor Status

1989 • 212 citations

High-dose treatment with lanreotide of patients with advanced neuroendocrine gastrointestinal tumors: Clinical and biological effects

1997 • 192 citations

Preoperative Treatment of Acromegaly with Long-Acting Somatostatin Analog SMS 201-995: Shrinkage of Invasive Pituitary Macroadenomas and Improved Surgical Remission Rate*

1988 • 191 citations

Clinical review 75: Recent advances in pathogenesis, diagnosis, and management of acromegaly.

1995 • 188 citations

Molecular biology of somatostatin receptors

1995 • 178 citations

Mechanisms of Antineoplastic Action of Somatostatin Analogs

1998 • 166 citations

Long Term Effect of Incremental Doses of the Somatostatin Analog SMS 201–995 in 58 Acromegalic Patients*

1990 • 134 citations

A somatostatin analogue inhibits chondrosarcoma and insulinoma tumour growth

1985 • 104 citations

Cell Cycle Dependent Induction of Apoptosis by Somatostatin Analog SMS 201-995 in AtT-20 Mouse Pituitary Cells

1995 • 99 citations

Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors.

1991 • 99 citations

Somatostatin-14 and its analog octreotide exert a cytostatic effect on GH3 rat pituitary tumor cell proliferation via a transient G0/G1 cell cycle block.

1995 • 94 citations

Inhibition of Human Breast Cancer Cell (MCF-7) Growthin Vitroby the Somatostatin Analog SMS 201-995: Effects on Cell Cycle Parameters and Apoptotic Cell Death*

1991 • 82 citations

Determination of the Proliferation and Apoptotic Index in Adrenocorticotropin-Secreting Pituitary Tumors

2000 • 80 citations

Somatostatin Inhibits PC Cl3 Thyroid Cell Proliferation through the Modulation of Phosphotyrosine Phosphatase Activity

1996 • 71 citations

Apoptosis in Nontumorous and Neoplastic Human Pituitaries

1999 • 70 citations

SMS 201.995 inhibits in vitro and in vivo growth of human colon cancer.

1992 • 64 citations

Morphological effects of octreotide on growth hormone-producing pituitary adenomas.

1994 • 58 citations

Growth of Human Breast Cancer Cell Lines Is Inhibited by the Somatostatin Analog BIM23014*

1991 • 51 citations

Detection of DNA strand breaks associated with apoptosis in human brain tumors

1995 • 46 citations

Antiproliferative Effect of the Somatostatin Analogue Octreotide on Growth Hormone-Producing Pituitary Tumors: Results of a Multicenter Randomized Trial

1997 • 45 citations

Apoptosis in human pituitary adenomas: a morphologic and in situ end-labeling study.

1997 • 40 citations

Apoptosis and p53 suppressor gene protein expression in human anterior pituitary adenomas

1997 • 33 citations

Morphological effects of octreotide on growth hormone-producing pituitary adenomas

1994 • 27 citations

Molecular basis for somatostatin action: inhibition of c-fos expression and AP-1 binding

1994 • 26 citations

Short Term Treatment of Acromegaly with the Somatostatin Analog Octreotide: The First Double-Blind Randomized Placebo-Controlled Study on Its Effects

1990 • 22 citations

Absence of apoptosis in somatotropinomas treated with octreotide

1997 • 19 citations

Experience of a Six-Month Treatment with Sandostatin at Increasing Doses in Acromegaly

1989 • 18 citations

Usefulness of markers of cell proliferation in the management of pituitary adenomas

1998 • 18 citations

Effects of somatostatin on somatotroph adenomas of the human pituitary: An in vitro functional and morphological study

1990 • 16 citations

Hypothalamic hormonal regulation of human growth hormone gene expression in somatotroph adenoma cell cultures

1990 • 14 citations

Effect of treatment with octreotide on the morphology of growth hormone—secreting pituitary adenomas: Study of 24 cases

1991 • 13 citations

Effects of Octreotide on Morphology of Pituitary Adenomas in Acromegaly

1993 • 13 citations