Antinociceptive Effects and Central Nervous System Depression Caused by Oxycodone and Morphine in Rats

Chronic catheterization of the spinal subarachnoid space

1976 • 2,244 citations

Opiates and endogenous opioid peptides

1977 • 1,282 citations

In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of mu, delta and kappa receptors with visceral chemical and cutaneous thermal stimuli in the rat.

1984 • 391 citations

Clinical Pharmacokinetics: Concepts and Applications

1989 • 276 citations

Factors affecting the action of narcotics

1978 • 243 citations

Intrathecal opioids, potency and lipophilicity

1989 • 158 citations

Morphine and Oxycodone in the Management of Cancer Pain: Plasma Levels Determined by Chemical and Radioreceptor Assays

1990 • 98 citations

Analgesic studies of codeine and oxycodone in patients with cancer. II. Comparisons of intramuscular oxycodone with intramuscular morphine and codeine.

1978 • 95 citations

The effect of narcotic analgesics on the homovanillic acid content of rat nucleus caudatus

1973 • 81 citations

Synthetic substances with morphine-like effect; relationship between analgesic action and addiction liability, with a discussion of the chemical structure of addiction-producing substances.

1956 • 67 citations

Utility of the neurological examination in rats.

1980 • 64 citations

Influence of polarity on dose-response relationships of intrathecal opioids in rats

1990 • 61 citations

Antagonism of dermorphin-induced catalepsy with naloxone, TRH-analog CG3703 and the benzodiazepine antagonist, Ro 15-1788

1988 • 58 citations

Intrathecal etorphine, fentanyl and buprenorphine on spinal nociceptive neurones in the rat

1990 • 52 citations

Antagonism by amantadine of prochlorpemazine-induced catalepsy

1970 • 46 citations

Psychomotor, Respiratory and Neuroendocrinological Effects of a μ‐Opioid Receptor Agonist (Oxycodone) in Healthy Volunteers

1989 • 44 citations

Epidural and Subcutaneous Morphine, Meperidine (pethidine), Fentanyl and Sufentanil in the Rat

1987 • 40 citations

Effect of muscarinic cholinergic drugs on morphine-induced catalepsy, antinociception and changes in brain dopamine metabolism

1977 • 35 citations

Analgesics in postoperative pain relief.

1978 • 32 citations