Induction of cyclooxygenase-2 mRNA in gerbil hippocampal neurons after transient forebrain ischemia

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1995 • 2,308 citations

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.

1993 • 1,655 citations

Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids

1993 • 1,222 citations

‘Ischemic tolerance’ phenomenon found in the brain

1990 • 1,098 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Nonsteroidal Antiinflammatory Drugs — Differences and Similarities

1991 • 756 citations

A Comparison of Two Doses of Aspirin (30 mg vs. 283 mg a Day) in Patients after a Transient Ischemic Attack or Minor Ischemic Stroke

1991 • 747 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

Arachidonic Acid Cascade and Signal Transduction

1990 • 597 citations

Swedish Aspirin Low-dose Trial (SALT) of 75 mg aspirin as secondary prophylaxis after cerebrovascular ischaemic events

1991 • 525 citations

Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis.

1980 • 481 citations

Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide.

1995 • 477 citations

Nonsteroidal Antiinflammatory Drugs

1980 • 398 citations

Accumulation of Cyclooxygenase Products of Arachidonic Acid Metabolism in Gerbil Brain During Reperfusion After Bilateral Common Carotid Artery Occlusion

1980 • 367 citations

NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions

1993 • 348 citations

Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain; its possible role in the febrile response

1995 • 252 citations

Cyclooxygenase‐2 Induction in Cerebral Cortex: An Intracellular Response to Synaptic Excitation

1996 • 201 citations

A proteolipid protein gene family: Expression in sharks and rays and possible evolution from an ancestral gene encoding a pore-forming polypeptide

1993 • 150 citations

Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain

1995 • 123 citations

Indomethacin ameliorates ischemic neuronal damage in the gerbil hippocampal CA1 sector.

1988 • 95 citations

Reperfusion induces 5-lipoxygenase translocation and leukotriene C4 production in ischemic brain

1995 • 77 citations

Immunohistochemical demonstration of increase in prostaglandin F2-alpha after recirculation in global ischemic rat brains

1987 • 28 citations

Immunohistochemical demonstration of transient increase in prostaglandin F2-alpha after recirculation in global ischemic rat brains

1988 • 8 citations