Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

2007 • 19,034 citations

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

2001 • 10,602 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

DAVID: Database for Annotation, Visualization, and Integrated Discovery

2003 • 8,668 citations

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

2008 • 8,256 citations

Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer

2005 • 5,199 citations

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

2004 • 3,727 citations

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

1998 • 2,266 citations

Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery

2005 • 2,090 citations

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

2008 • 1,755 citations

Molecular Definition of Breast Tumor Heterogeneity

2007 • 1,338 citations

The molecular portraits of breast tumors are conserved across microarray platforms

2006 • 1,320 citations

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

2006 • 1,296 citations

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

2007 • 1,219 citations

An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer

2008 • 1,002 citations

High-throughput oncogene mutation profiling in human cancer

2007 • 995 citations

The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells

2007 • 985 citations

Assembly of microarrays for genome-wide measurement of DNA copy number

2001 • 948 citations

A faster circular binary segmentation algorithm for the analysis of array CGH data

2007 • 937 citations

The anaplastic lymphoma kinase in the pathogenesis of cancer

2007 • 841 citations

The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis

2007 • 835 citations

PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma

2005 • 831 citations

Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism

2006 • 735 citations

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

2006 • 699 citations

Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome

2006 • 573 citations

Pathology of the breast

1992 • 544 citations

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells

2003 • 439 citations

Estrogen-Regulated Genes Predict Survival in Hormone Receptor–Positive Breast Cancers

2006 • 350 citations

Metaplastic breast carcinomas are basal‐like tumours

2006 • 343 citations

Metaplastic carcinomas of the breast. II. Spindle cell carcinoma

1989 • 329 citations

Targeting Mammalian Target of Rapamycin Synergistically Enhances Chemotherapy-Induced Cytotoxicity in Breast Cancer Cells

2004 • 322 citations

Breast tumor copy number aberration phenotypes and genomic instability

2006 • 291 citations

Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma

2005 • 276 citations

B-Crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer

2005 • 275 citations

Statistical Significance of Clustering for High-Dimension, Low–Sample Size Data

2008 • 256 citations

Metaplastic carcinomas of the breast

1999 • 234 citations

Non-parametric quantification of protein lysate arrays

2007 • 224 citations

Biphasic metaplastic sarcomatoid carcinoma of the breast

2006 • 211 citations

Squamous Cell Carcinoma of the Breast

2005 • 205 citations

Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay

2006 • 204 citations

Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial–mesenchymal transition

2007 • 202 citations

Determination of Stromal Signatures in Breast Carcinoma

2005 • 195 citations

Genetic Changes of Wnt Pathway Genes Are Common Events in Metaplastic Carcinomas of the Breast

2008 • 161 citations

Pharmacodynamic Markers of Perifosine Efficacy

2007 • 130 citations

Spindle-cell carcinoma: A case report

1990 • 124 citations

High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines

2004 • 121 citations

Phosphoinositide-3-Kinase Signaling Controls S-Phase Kinase–Associated Protein 2 Transcription via E2F1 in Pancreatic Ductal Adenocarcinoma Cells

2007 • 103 citations

Gamma-S crystallin gene (CRYGS) mutation causes dominant progressive cortical cataract in humans

2005 • 101 citations

Sarcomatoid neoplasms of the breast: proposed definitions for biphasic and monophasic sarcomatoid mammary carcinomas.

1993 • 90 citations

Biologic distinctions and therapeutic implications of sarcomatoid metaplasia of epithelial carcinoma of the breast.

1995 • 84 citations

Regulation of an epitope-tagged recombinant Rsk-1 S6 kinase by phorbol ester and erk/MAP kinase

1993 • 73 citations

Akt-induced promotion of cell-cycle progression at G2/M phase involves upregulation of NF-Y binding activity in PC12 cells

2005 • 65 citations

PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells

2005 • 59 citations

Y-box binding protein, YB-1, as a marker of tumor aggressiveness and response to adjuvant chemotherapy in breast cancer

2005 • 58 citations

Involvement of the serine/threonine p70S6 kinase in TGF-β1-induced ADAM12 expression in cultured human hepatic stellate cells

2005 • 55 citations