Treatment with drugs to lower blood pressure and blood cholesterol based on an individual's absolute cardiovascular risk

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

2002 • 9,810 citations

Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients

2000 • 8,612 citations

Cost-Effectiveness in Health and Medicine

1996 • 6,853 citations

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

2002 • 6,780 citations

Markers of Inflammation and Cardiovascular Disease

2003 • 6,067 citations

Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project

2003 • 5,083 citations

Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes

2004 • 4,752 citations

Blood pressure, stroke, and coronary heart disease *1Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias

1990 • 4,310 citations

Sick individuals and sick populations

2001 • 3,588 citations

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack

2001 • 3,093 citations

Recommendations of the Panel on Cost-Effectiveness in Health and Medicine

1996 • 2,447 citations

Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials

2003 • 2,365 citations

Cardiovascular disease risk profiles

1991 • 2,170 citations

Validation of the Framingham Coronary Heart Disease Prediction Scores

2001 • 2,076 citations

Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials

2000 • 1,789 citations

Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT)

1986 • 1,758 citations

Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis

2003 • 1,718 citations

West of Scotland Coronary Prevention Study: identification of high-risk groups and comparison with other cardiovascular intervention trials

1996 • 1,584 citations

A strategy to reduce cardiovascular disease by more than 80%

2003 • 1,553 citations

Simple Scoring Scheme for Calculating the Risk of Acute Coronary Events Based on the 10-Year Follow-Up of the Prospective Cardiovascular Münster (PROCAM) Study

2002 • 1,547 citations

Effect of Statins on Risk of Coronary Disease

1999 • 1,257 citations

Is Relationship Between Serum Cholesterol and Risk of Premature Death From Coronary Heart Disease Continuous and Graded?

1986 • 1,248 citations

By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease?

1994 • 1,235 citations

A Prospective Study of Triglyceride Level, Low-Density Lipoprotein Particle Diameter, and Risk of Myocardial Infarction

1996 • 1,065 citations

The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56)

2001 • 1,064 citations

Cholesterol, diastolic blood pressure, and stroke: 13 000 strokes in 450 000 people in 45 prospective cohorts

1995 • 852 citations

Serum Cholesterol, Blood Pressure, Cigarette Smoking, and Death From Coronary Heart Disease Overall Findings and Differences by Age for 316099 White Men

1992 • 778 citations

Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group

1992 • 704 citations

Blood Pressure and Stroke

2004 • 699 citations

Blood pressure and cardiovascular disease in the Asia Pacific region

2003 • 616 citations

Primary and subsequent coronary risk appraisal: New results from the Framingham study

2000 • 570 citations

Predictive accuracy of the Framingham coronary risk score in British men: prospective cohort study

2003 • 520 citations

Blood pressure, cholesterol, and stroke in eastern Asia

1998 • 502 citations

Some lessons in cardiovascular epidemiology from Framingham

1976 • 479 citations

Cholesterol, coronary heart disease, and stroke in the Asia Pacific region

2003 • 374 citations

Risk factor thresholds: their existence under scrutiny

2002 • 276 citations

Evaluation of computer based clinical decision support system and risk chart for management of hypertension in primary care: randomised controlled trial

2000 • 273 citations

Management of raised blood pressure in New Zealand: a discussion document.

1993 • 270 citations

A score for predicting risk of death from cardiovascular disease in adults with raised blood pressure, based on individual patient data from randomised controlled trials

2001 • 265 citations

Updated New Zealand cardiovascular disease risk-benefit prediction guide

2000 • 235 citations

Hypertension in the Elderly

1994 • 210 citations

Vascular viewpoint

2003 • 207 citations

Fatality outside hospital from acute coronary events in three British health districts, 1994-5

1998 • 198 citations

World Health report 2002: reducing risks, promoting health life

2002 • 190 citations

Coronary and cardiovascular risk estimation for primary prevention: validation of a new Sheffield table in the 1995 Scottish health survey population

2000 • 186 citations

The Framingham Study : ITS 50-Year Legacy and Future Promise

2000 • 152 citations

Prediction of risk of coronary events in middle-aged men in the Prospective Cardiovascular Münster Study (PROCAM) using neural networks

2002 • 146 citations

Joint British recommendations on prevention of coronary heart disease in clinical practice: summary

2000 • 146 citations

Blood Pressure Management: Individualized Treatment Based on Absolute Risk and the Potential for Benefit

1993 • 120 citations

Differences in Generalists' and Cardiologists' Perceptions of Cardiovascular Risk and the Outcomes of Preventive Therapy in Cardiovascular Disease

1996 • 113 citations

Prediction of mortality from coronary heart disease among diverse populations: is there a common predictive function?

2002 • 94 citations

Are preventive drugs preventive enough? A study of patients’ expectation of benefit from preventive drugs

2002 • 93 citations

Controlled trial of effect of documented cardiovascular risk scores on prescribing

2003 • 87 citations

Can Computerized Risk Profiles Help Patients Improve Their Coronary Risk? The Results of The Coronary Health Assessment Study (CHAS)

1998 • 81 citations

Blood Pressure and Coronary Heart Disease: A Review of the Evidence

2002 • 72 citations

Resource management in prevention of coronary heart disease: optimising prescription of lipid-lowering drugs

2002 • 63 citations

Risk assessment in primary prevention of coronary heart disease: randomised comparison of three scoring methods

2000 • 55 citations

Estimating an Individual's True Cholesterol Level and Response to Intervention

1991 • 54 citations

What is the optimal age for starting lipid lowering treatment? A mathematical model

2000 • 39 citations

Infopoints: A web-based system for individualised survival estimation in breast cancer

2003 • 35 citations

Framingham Heart Study risk equation predicts first cardiovascular event rates in New Zealanders at the population level.

2003 • 32 citations

Deleted Work

1955 • 0 citations