How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Organ-Specific Disease Provoked by Systemic Autoimmunity

1996 • 880 citations

Arthritis Critically Dependent on Innate Immune System Players

2002 • 694 citations

From Systemic T Cell Self-Reactivity to Organ-Specific Autoimmune Disease via Immunoglobulins

1999 • 689 citations

Arthritis Provoked by Linked T and B Cell Recognition of a Glycolytic Enzyme

1999 • 620 citations

The Immunopathology of Joint Inflammation in Rheumatoid Arthritis

1973 • 561 citations

Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H.

1990 • 416 citations

Regulation by membrane sialic acid of β1H-dependent decay-dissociation of amplification C3 convertase of the alternative complement pathway

1978 • 415 citations

Arthritogenic Monoclonal Antibodies from K/BxN Mice

2002 • 229 citations

Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease

2001 • 212 citations

Modulation of Renal Disease in MRL/lpr Mice Genetically Deficient in the Alternative Complement Pathway Factor B

2000 • 197 citations

Identification of immunoglobulins and complement in rheumatoid articular collagenous tissues

1975 • 196 citations

Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor

1991 • 179 citations

Genetic Influences on the End-Stage Effector Phase of Arthritis

2001 • 149 citations

Crystal Structure of Rabbit Phosphoglucose Isomerase, a Glycolytic Enzyme That Moonlights as Neuroleukin, Autocrine Motility Factor, and Differentiation Mediator^,

2000 • 140 citations

C3b covalently bound to IgG demonstrates a reduced rate of inactivation by factors H and I.

1984 • 134 citations

Dynamic visualization of a joint-specific autoimmune response through positron emission tomography

2002 • 123 citations

Does properdin crosslink the cellular and the humoral immune response?

1999 • 118 citations

The crystal structure of a multifunctional protein: Phosphoglucose isomerase/autocrine motility factor/neuroleukin

1999 • 110 citations

Molecular Basis for Recognition of an Arthritic Peptide and a Foreign Epitope on Distinct MHC Molecules by a Single TCR

2000 • 81 citations

Electron microscopic demonstration of immunoglobulin deposition in rheumatoid cartilage

1975 • 75 citations

Identification of a major binding site for complement C3 on the IgG1 heavy chain.

1993 • 56 citations

Cloning and cDNA sequence analysis of nephritogenic monoclonal antibodies derived from an MRL/lpr lupus mouse

1993 • 51 citations

Interaction of C3b2‒IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification

2000 • 45 citations

Death of mouse embryos that lack a functional gene for glucose phosphate isomerase

1990 • 34 citations

The covalent interaction of C3 with IgG immune complexes

1999 • 28 citations

Immune deposits in articular cartilage of patients with rheumatoid arthritis have a granular pattern not seen in osteoarthritis

1990 • 26 citations

Interaction of C3b2–IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification

2000 • 18 citations

Glomerular Deposition of Immune Complexes Made with IgG2a Monoclonal Antibodies

2000 • 16 citations

Immune Mediated Cartilage Destruction

1988 • 13 citations

Cellular immune mechanisms in rheumatoid arthritis and other inflammatory arthritides

1993 • 11 citations