Characterization of Insulin-Like Growth Factor (IGF)-I-Receptor Binding Sites during In Vitro Transformation of Rat Hepatic Stellate Cells to Myofibroblasts

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

J. Submicrosc. Cytol. Pathol.

2000 • 2,783 citations

An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I.

1987 • 682 citations

Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors.

1989 • 401 citations

Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis

1991 • 386 citations

Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture.

1992 • 340 citations

Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers.

1991 • 334 citations

Insulin-Like Growth Factor I (IGF-I)-Binding Protein Complex Is a Better Mitogen than Free IGF-I*

1989 • 318 citations

Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumorigenicity.

1995 • 314 citations

Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells.

1984 • 299 citations

Alcoholic liver injury in baboons: Transformation of lipocytes to transitional cells

1984 • 275 citations

The synthesis of proteoglycans in fat-storing cells of rat liver

1987 • 259 citations

Molecular Mechanisms of Liver Fibrogenesis – A Homage to the Role of Activated Fat-Storing Cells

1995 • 237 citations

The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver

1992 • 212 citations

Lipocytes and transitional cells in alcoholic liver disease: A morphometric study

1988 • 187 citations

In vitro differentiation of fat-storing cells parallels marked increase of collagen synthesis and secretion

1989 • 175 citations

Characterization of insulinlike growth factor I receptors in human colon cancer

1992 • 174 citations

Desmin and actin in the identification of Ito cells and in monitoring their evolution to myofibroblasts in experimental liver fibrosis

1988 • 153 citations

Connective tissue biology and hepatic fibrosis: Report of a conference

1990 • 129 citations

Liver fibrosis: perspectives in pathobiochemical research and clinical outlook.

1991 • 119 citations

Production of Insulin-Like Growth Factor I and Its Binding Protein by Adult Rat Hepatocytes in Primary Culture*

1985 • 115 citations

Early alcoholic liver injury

1986 • 115 citations

The gene encoding rat insulinlike growth factor-binding protein 1 is rapidly and highly induced in regenerating liver.

1991 • 110 citations

Application of an NaOH maceration method to a scanning electron microscopic observation of Ito cells in the rat liver.

1986 • 109 citations

Modulation of hepatic lipocyte proteoglycan synthesis and proliferation by Kupffer cell-derived transforming growth factors type β1 and type α

1990 • 103 citations

Rat Hepatocyte Insulin-Like Growth Factor I and Binding Protein: Effect of Growth Hormonein Vitroandin Vivo*

1985 • 91 citations

Expression of Insulin-Like Growth Factor I in Cultured Rat Hepatocytes: Effects of Insulin and Growth Hormone

1989 • 82 citations

Perisinusoidal lipocytes and fibrogenesis.

1994 • 74 citations

Phenotypic modulation in lipocytes in experimental liver fibrosis

1991 • 74 citations

Secretion of Insulin-Like Growth Factor-I and Binding Proteins by Rat Liver Fat-Storing Cells: Regulatory Role of Platelet-Derived Growth Factor*

1990 • 73 citations

Identification andin SituLocalization of the Insulin-Like Growth Factor-II/Mannose-6-Phosphate (IGF-II/M6P) Receptor in the Rat Gastrointestinal Tract: Comparison with the IGF-I Receptor*

1991 • 68 citations

Identification and partial characterization of a hepatocyte-derived factor promoting proliferation of cultured fat-storing cells (parasinusoidal lipocytes)

1992 • 67 citations

The Differential Regulation by Glucagon and Growth Hormone of Insulin-Like Growth Factor (IGF)-I and IGF Binding Proteins in Cultured Rat Hepatocytes*

1991 • 64 citations

Molecular dissection of the mitogenic effect of hepatocytes on cultured hepatic stellate cells

1995 • 63 citations

The parasinusoidal cells of the liver: A historical account

1986 • 63 citations

The signaling potential of the receptors for insulin and insulin‐like growth factor I (IGF‐I) in 3t3‐l1 adipocytes: Comparison of glucose transport activity, induction of oncogene c‐fos, glucose transporter mRNA, and DNA‐synthesis

1991 • 60 citations

Developmentally regulated transcription of Dictyostelium discoideum plasmid Ddp1

1985 • 49 citations

Insulin‐Like Growth Factor Receptors

1991 • 48 citations

Growth hormone induction of insulin-like growth factor I messenger RNA in primary cultures of rat liver cells

1987 • 48 citations

Cellular communications and cell-matrix interactions in the pathogenesis of fibroproliferative diseases: liver fibrosis as a paradigm.

1994 • 43 citations

Fat-storing cells and liver fibrosis

1996 • 39 citations

Expression of insulin-like growth factor II (IGF-II) and IGF-II, IGF-I and insulin receptors mRNAs in isolated non-parenchymal rat liver cells

1992 • 35 citations

Time-Related Distribution Profiles of Sulfated Glycosaminoglycans in Cells, Cell Surfaces, and Media of Cultured Rat Liver Fat-Storing Cells

1991 • 29 citations

Cytoskeleton of liver perisinusoidal cells (lipocytes) in normal and pathological conditions

1992 • 26 citations

Hepatocyte-conditioned medium potentiates insulin-like growth factor (IGF) 1 and 2 stimulated DNA synthesis of cultured fat storing cells

1993 • 21 citations

Cellular distribution of somatogenic receptors and insulin-like growth factor-I mRNA in the rat liver

1988 • 20 citations

Expression of insulin-like growth factor II and receptors for insulin-like growth factor II, insulin-like growth factor I and insulin in isolated and cultured rat hepatocytes

1991 • 19 citations

Pitfalls in Insulin-Like Growth Factor (IGF) Receptor Binding Studies Using Cells in Monolayer Culture

1991 • 5 citations

Deleted Work

1955 • 0 citations