Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus.

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Positive and negative selection of an antigen receptor on T cells in transgenic mice

1988 • 758 citations

Genes and Antibodies

1959 • 675 citations

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

1988 • 618 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

T Cell Selection in the Thymus

1988 • 405 citations

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells.

1989 • 331 citations

The effect of thymus environment on T cell development and tolerance

1988 • 330 citations

Does T-cell tolerance require a dedicated antigen-presenting cell?

1989 • 288 citations

Positive selection of the T cell repertoire: Where and when does it occur?

1989 • 242 citations

Class discrimination in the world of immunology

1987 • 214 citations

Bone marrow origin of Ia-positive cells in the medulla rat thymus.

1981 • 197 citations

The T-cell repertoire for antigen and MHC

1988 • 180 citations

Positive selection of CD4+ thymocytes controlled by MHC class II gene products

1988 • 174 citations

Deletion of self-reactive T cells before entry into the thymus medulla

1988 • 171 citations

Studies on Tolerance of the Y Chromosome Antigen in Mice

1960 • 161 citations

T-cell receptor-specific monoclonal antibodies against a V ? 11-positive mouse T-cell clone

1988 • 139 citations

Positive selection of CD4-CD8+ T cells in the thymus of normal mice

1989 • 81 citations

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa.

1989 • 76 citations