Development of graft-vs.-host disease-like syndrome in cyclosporine-treated rats after syngeneic bone marrow transplantation. I. Development of cytotoxic T lymphocytes with apparent polyclonal anti-Ia specificity, including autoreactivity.

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

Biological effects of cyclosporin A: A new antilymphocytic agent

1976 • 1,501 citations

Effects of the new anti-lymphocytic peptide cyclosporin A in animals.

1977 • 710 citations

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1981 • 632 citations

Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens.

1981 • 338 citations

Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution.

1983 • 285 citations

Natural killer (NK) cell activity in the rat. I. Isolation and characterization of the effector cells.

1981 • 284 citations

Comparative study of in vitro and in vivo drug effects on cell-mediated cytotoxicity.

1976 • 265 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR.

1980 • 239 citations

PROLONGED SURVIVAL OF PIG ORTHOTOPIC HEART GRAFTS TREATED WITH CYCLOSPORIN A

1978 • 209 citations

EXTENSIVE PROLONGATION OF RABBIT KIDNEY ALLOGRAFT SURVIVAL AFTER SHORT-TERM CYCLOSPORIN-A TREATMENT

1978 • 177 citations

Use of cyclosporin A in allogeneic bone marrow transplantation in the rat

1979 • 105 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. IV. Production of T cell stimulatory growth factors and development of responsiveness to these growth factors in CsA-treated primary MLR cultures.

1982 • 103 citations

Effect of cyclosporin A on human lymphocyte responses in vitro. II. Induction of specific alloantigen unresponsiveness mediated by a nylon wool adherent suppressor cell.

1981 • 77 citations

Macrophages Suppress CTL Generation in Rat Mixed Leukocyte Cultures

1977 • 68 citations

Suppressive effects of cyclosporin A on the induction of alloreactivity in vitro and in vivo.

1981 • 66 citations

Sequential morphology of graft-versus-host disease in the rat radiation chimera

1982 • 60 citations

Mode of action of cyclosporin A: a new immunosuppressive agent.

1979 • 35 citations

Cyclosporin A.

1981 • 28 citations

Mechanisms of cardiac allograft prolongation by cyclosporin-A.

1981 • 6 citations