Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat.

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat.

1986 • 892 citations

Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica

1980 • 615 citations

Radioimmunoassay Measurement of Prostaglandins E, A, and F in Human Plasma

1973 • 478 citations

Hypoxia releases a vasoconstrictor substance from the canine vascular endothelium.

1985 • 461 citations

Role of endothelium in dilator responses of spontaneously hypertensive rat arteries.

1983 • 414 citations

Human Pulmonary Endothelial Cells in Culture

1980 • 233 citations

Bioassay of endothelium-derived relaxing factor(s): inactivation by catecholamines

1985 • 154 citations

Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase

1985 • 153 citations

Comparative pharmacology of EDRF and nitric oxide on vascular strips

1987 • 140 citations

Endothelium-dependent contractions to calcium ionophore A23187, arachidonic acid, and acetylcholine in canine basilar arteries.

1988 • 136 citations

Acetylcholine-induced contractions in isolated rabbit pulmonary arteries: role of thromboxane A2.

1986 • 111 citations

Effects of prostacyclin on the canine isolated basilar artery

1979 • 88 citations

Nature of endothelium-derived relaxing factor: are there two relaxing mediators?

1987 • 82 citations

Effect of age on blood pressure and membrane-dependent vascular responses in the rat.

1987 • 81 citations

The effect of prostacyclin on the human umbilical artery

1978 • 62 citations

In vitro and in vivo effects of new powerful thromboxane antagonists (3-alkylamino pinane derivatives).

1983 • 59 citations

The stimulatory effect of prostacyclin (PGI2) on isolated rabbit and rat aorta is probably associated to the generation of a thromboxane A2 (TXA2) "like-material".

1983 • 17 citations

Role of the vascular endothelium in the contractile response to prostacyclin in the isolated rat aorta.

1986 • 15 citations