The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

1997 • 2,762 citations

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

1997 • 2,184 citations

Conserved Structures and Diversity of Functions of RNA-Binding Proteins

1994 • 1,873 citations

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1

1993 • 1,596 citations

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

1997 • 1,283 citations

Ataxin-1 Nuclear Localization and Aggregation

1998 • 959 citations

Intranuclear Inclusions of Expanded Polyglutamine Protein in Spinocerebellar Ataxia Type 3

1997 • 821 citations

Identification of genes that modify ataxin-1-induced neurodegeneration

2000 • 659 citations

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

1992 • 619 citations

SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

1995 • 582 citations

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

1997 • 528 citations

Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I

1993 • 473 citations

Intranuclear Neuronal Inclusions in Huntington's Disease and Dentatorubral and Pallidoluysian Atrophy: Correlation between the Density of Inclusions andIT15CAG Triplet Repeat Length

1998 • 421 citations

Proteins with leucine-rich repeats

1995 • 388 citations

Identification and characterization of the gene causing type 1 spinocerebellar ataxia

1994 • 369 citations

Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions

1998 • 338 citations

Expression analysis of the ataxin–1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

1995 • 294 citations

The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1

1997 • 249 citations

Heterogeneous nuclear RNA-protein fibers in chromatin-depleted nuclei.

1978 • 245 citations

A novel protein with RNA-binding motifs interacts with ataxin-2

2000 • 218 citations

Association of nuclear matrix antigens with exon-containing splicing complexes.

1994 • 214 citations

The RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation

1996 • 189 citations

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

2000 • 95 citations

A family of ubiquitin‐like proteins binds the ATPase domain of Hsp70‐like Stch

2000 • 91 citations

A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons.

1994 • 76 citations

Isolation of bacterial and phage proteins by homopolymer RNA-cellulose chromatography.

1975 • 73 citations