INTERACTIONS OF PLASMA LIPOPROTEINS WITH ENDOTHELIAL CELLS*

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

Electrophoretic separation of plasma lipoproteins in agarose gel

1968 • 1,332 citations

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

1980 • 851 citations

Hyperlipidemia and Atherosclerosis

1976 • 746 citations

The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

1980 • 727 citations

The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages

1980 • 543 citations

LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture

1979 • 512 citations

The Metabolic Role of Lecithin: Cholesterol Acyltransferase: Perspectives from Pathology

1973 • 480 citations

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

1980 • 475 citations

George Lyman Duff Memorial Lecture. Atherosclerosis: a problem of the biology of arterial wall cells and their interactions with blood components.

1981 • 456 citations

Reticulum Cell Sarcoma: An Effector Cell in Antibody-Dependent Cell-Mediated Immunity

1975 • 426 citations

Dietary induced atherogenesis in swine. Morphology of the intima in prelesion stages.

1979 • 393 citations

Cholesteryl ester accumulation in macrophages resulting from receptor-mediated uptake and degradation of hypercholesterolemic canine beta-very low density lipoproteins.

1980 • 377 citations

A Proposal Linking Atherogenesis to the Interaction of Endothelial Lipoprotein Lipase with Triglyceride-Rich Lipoproteins

1973 • 339 citations

Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. IV. Investigation of macrophage-like properties of aortic cell populations.

1979 • 297 citations

Factors regulating the activities of the low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages.

1981 • 234 citations

Evidence for a lipoprotein carrier in human plasma catalyzing sterol efflux from cultured fibroblasts and its relationship to lecithin:cholesterol acyltransferase.

1981 • 197 citations

Effect of high and low density lipoproteins on proliferation of cultured bovine vascular endothelial cells.

1980 • 185 citations

The metabolism of native and malondialdehyde-altered low density lipoproteins by human monocyte-macrophages

1981 • 185 citations

Role of contact inhibition in the regulation of receptor-mediated uptake of low density lipoprotein in cultured vascular endothelial cells.

1978 • 177 citations

Vascular wall growth control: the role of the endothelium.

1981 • 176 citations

Secretion of lipoprotein lipase by macrophages in culture.

1981 • 173 citations

Fine structure of human aortic intimal thickening and fatty streaks.

1965 • 168 citations

High density lipoproteins reduce the uptake of low density lipoproteins by human endothelial cells in culture

1976 • 154 citations

Uptake and degradation of low density lipoprotein by swine arterial smooth muscle cells with inhibition of cholesterol biosynthesis

1976 • 153 citations

The removal of cholesterol from landschütz ascites cells by high-density apolipoprotein

1973 • 142 citations

Role of endothelium and hypercholesterolemia in intimal thickening and lipid accumulation.

1979 • 129 citations

Body Weight, Skeletal Muscle Morphology, and Enzyme Activities in Relation to Fasting Serum Insulin Concentration and Glucose Tolerance in 48-year-old Men

1981 • 127 citations

Endothelial surface characteristics in pigeon coronary artery atherosclerosis. I. Cellular alterations during the initial stages of dietary cholesterol challenge.

1982 • 114 citations

Electron-microscopic studies in human atherosclerosis cellular elements in aortic fatty streaks

1964 • 111 citations

Lipoproteins and the inhibitory effect of human endothelial cells on platelet function.

1978 • 110 citations

Effect of contact inhibition on the regulation of cholesterol metabolism in cultured vascular endothelial cells.

1979 • 88 citations

Lipoprotein lipase secretion by human monocytes and rabbit alveolar macrophages in culture.

1982 • 81 citations

Metabolism of cholesterol-rich chylomicroms. Mechanism of binding and uptake of cholesteryl esters by the vascular bed of the perfused rat heart.

1978 • 79 citations

Endothelium modifies the altered metabolism of the injured aortic wall.

1981 • 78 citations

Lipoprotein and cholesterol metabolism in rabbit arterial endothelial cells in culture

1978 • 77 citations

Characteristics of chylomicron binding and lipid uptake by endothelial cells in culture.

1979 • 73 citations

Endothelial injury and atherosclerosis

1979 • 67 citations

Injury to cultured endothelial cells induced by low density lipoproteins: protection by high density lipoproteins

1979 • 60 citations

Distortion of endothelial repair The effect of hypercholesterolaemia on regeneration of aortic endothelium following injury by endotoxin A scanning electron microscope study

1978 • 55 citations

Early endothelial changes in experimental primate atherosclerosis.

1979 • 54 citations

Intimal and medial plasma protein concentrations and endothelial function

1982 • 46 citations

Endothelial lesions in the aorta of egg yolk-fed miniature swine: A study by scanning and transmission electron microscopy

1976 • 44 citations

Uptake and degradation of low density lipoproteins (LDL) by confluent, contact-inhibited bovine and human endothelial cells exposed to physiological concentrations of LDL

1979 • 39 citations

Scanning and transmission electron microscopy observations on the surface lining of aortic intimai plaques in rabbits on a hypercholesterolic diet

1974 • 37 citations

The Endothelium, Triglyceride-rich Lipoproteins, and Atherosclerosis: Insights from Cell Biology and Lipid Metabolism

1981 • 24 citations

Quantitative SEM analysis of injury to the endothelium of rabbit aorta and carotid artery during experimental atherosclerosis

1982 • 21 citations

The effect of serum lipoproteins on cholesterol content and sterol exchange in cultured human endothelial cells

1979 • 21 citations

Fine structure of spontaneous atherosclerosis of the aorta in the squirrel monkey.

1969 • 17 citations