Compilation and analysis of intein sequences

Amino acid substitution matrices from protein blocks.

1992 • 5,998 citations

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

The Minimal Gene Complement of Mycoplasma genitalium

1995 • 2,499 citations

Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii

1996 • 2,043 citations

Detecting Subtle Sequence Signals: a Gibbs Sampling Strategy for Multiple Alignment

1993 • 1,835 citations

A workbench for multiple alignment construction and analysis

1991 • 1,005 citations

INTRONS AS MOBILE GENETIC ELEMENTS

1993 • 618 citations

Autoproteolysis in hedgehog protein biogenesis

1994 • 541 citations

Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain

1996 • 529 citations

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1995 • 505 citations

Protein Splicing Converts the Yeast TFP1 Gene Product to the 69-kdDSubunit of the Vacuolar H ⁺ -Adenosine Triphosphatase

1990 • 485 citations

Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae.

1990 • 474 citations

REBASE--restriction enzymes and methylases

1999 • 368 citations

Protein splicing elements: inteins and exteins — a definition of terms and recommended nomenclature

1994 • 348 citations

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence Features in the 1 Mb Region from Map Positions 64% to 92% of the Genome

1995 • 301 citations

The mechanism of protein splicing and its modulation by mutation.

1996 • 278 citations

Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae

1992 • 275 citations

Mechanisms of Intron Mobility

1995 • 248 citations

Protein Splicing Involving the Saccharomyces cerevisiae VMA Intein

1996 • 245 citations

Protein splicing: an analysis of the branched intermediate and its resolution by succinimide formation.

1994 • 222 citations

In vitro protein splicing of purified precursor and the identification of a branched intermediate

1993 • 203 citations

Intervening sequences in an Archaea DNA polymerase gene.

1992 • 188 citations

Activation of Glycosylasparaginase

1996 • 180 citations

Thermostable DNA Polymerases

1996 • 178 citations

Conserved sequence features of inteins (protein introns) and their use in identifying new inteins and related proteins

1994 • 163 citations

Protein splicing in the maturation of M. tuberculosis RecA protein: A mechanism for tolerating a novel class of intervening sequence

1992 • 163 citations

Novel structure of the recA locus of Mycobacterium tuberculosis implies processing of the gene product

1991 • 139 citations

Sequence, organization, transcription and evolution of RNA polymerase subunit genes from the archaebacterial extreme halophiles Halobacterium halobium and Halococcus morrhuae

1989 • 137 citations

Intron mobility in the T-even phages: High frequency inheritance of group I introns promoted by intron open reading frames

1989 • 134 citations

Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision.

1993 • 125 citations

Protein splicing removes intervening sequences in an archaea DNA polymerase

1992 • 125 citations

Prokaryotic introns and inteins: a panoply of form and function

1995 • 113 citations

Substitutions in Conserved Dodecapeptide Motifs That Uncouple the DNA Binding and DNA Cleavage Activities of PI-SceI Endonuclease

1995 • 107 citations

Evidence of selection for protein introns in the recAs of pathogenic mycobacteria.

1994 • 106 citations

The Chlamydomonas chloroplast clpP gene contains translated large insertion sequences and is essential for cell growth

1994 • 89 citations

Reintedness of archaebacterial RNA polymerase core subunits to their eubacterial and eultaryotic equivalents

1988 • 82 citations

Protein Splicing: Evidence for an N−O Acyl Rearrangement as the Initial Step in the Splicing Process

1996 • 79 citations

Organization and nucleotide sequence of the genes encoding the large subunits A, B and C of the DNA-dependent RNA polymerase of the archaebacteriumSulfolobus acidocaldarius

1989 • 72 citations

Protein Splicing: Characterization of the Aminosuccinimide Residue at the Carboxyl Terminus of the Excised Intervening Sequence

1995 • 70 citations

Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae.

1993 • 64 citations

A site-specific endonuclease and co-conversion of flanking exons associated with the mobile td intron of phage T4

1989 • 63 citations

Peptide splicing in the vacuolar ATPase subunit A from Candida tropicalis.

1993 • 59 citations

Homing events in the gyrA gene of some mycobacteria.

1996 • 50 citations

A protein splice-junction motif in hedgehog family proteins

1995 • 46 citations

VDE endonuclease cleavesSaccharomyces cerevisiaegenomic DNA at a single site: physical mapping of theVMA1gene

1992 • 42 citations

Cloning and nucleotide sequence of the Bacillus subtilis ansR gene, which encodes a repressor of the ans operon coding for L-asparaginase and L-aspartase

1993 • 33 citations

Progress with the PRINTS protein fingerprint database

1996 • 30 citations

Nucleotide sequence of the genes encoding the subunits H, B, A′ and A″ of te DNA-dependent RNA polymerase and the initiator tRNA fromThermoplasma acidophilum

1992 • 16 citations

Enzymes and Proteins from Hyperthermophilic Microorganisms

1996 • 15 citations

Protozyme: Emerging Evidence in Nature1

1994 • 13 citations

Nucleotide sequence of the genes encoding the three largest subunits of the DNA-dependent RNA polymerase from the archaeumThermococcus celer

1992 • 11 citations

Protein splicing ? the lengths some proteins will go to

1995 • 6 citations