Tyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain

Current Protocols in Molecular Biology

1989 • 1,916 citations

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1993 • 1,026 citations

Spectrin and Ankyrin-Based Pathways: Metazoan Inventions for Integrating Cells Into Tissues

2001 • 915 citations

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1992 • 603 citations

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

1998 • 423 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

Cooperative interaction of S. pombe proteins required for mating and morphogenesis

1994 • 303 citations

βiv Spectrin, a New Spectrin Localized at Axon Initial Segments and Nodes of Ranvier in the Central and Peripheral Nervous System

2000 • 260 citations

On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton.

1993 • 235 citations

Kinesin Superfamily Protein 3 (Kif3) Motor Transports Fodrin-Associating Vesicles Important for Neurite Building

2000 • 200 citations

A novel peptide-SH3 interaction

1999 • 188 citations

Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactions.

1995 • 163 citations

SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55

2000 • 155 citations

An unusual beta-spectrin associated with clustered acetylcholine receptors.

1989 • 150 citations

Modulation of Erythrocyte Membrane Mechanical Function by β-Spectrin Phosphorylation and Dephosphorylation

1995 • 138 citations

A widely expressed βIII spectrin associated with Golgi and cytoplasmic vesicles

1998 • 138 citations

Tyrosine Phosphorylation Regulates the SH3-mediated Binding of the Wiskott-Aldrich Syndrome Protein to PSTPIP, a Cytoskeletal-associated Protein

1998 • 137 citations

Protein tyrosine phosphatase 1B negatively regulates integrin signaling

1998 • 136 citations

The role of ankyrin and spectrin in membrane transport and domain formation

1998 • 133 citations

Mutations in β-Spectrin Disrupt Axon Outgrowth and Sarcomere Structure

2000 • 126 citations

Mutant β-spectrin 4 causes auditory and motor neuropathies in quivering mice

2001 • 125 citations

Structural characterization of the phosphorylation sites of human erythrocyte spectrin.

1980 • 118 citations

Regulation of the Low Molecular Weight Phosphotyrosine Phosphatase by Phosphorylation at Tyrosines 131 and 132

1997 • 111 citations

Golgi membrane skeleton: identification, localization and oligomerization of a 195 kDa ankyrin isoform associated with the Golgi complex

1997 • 110 citations

Caenorhabditis elegans β-G Spectrin Is Dispensable for Establishment of Epithelial Polarity, but Essential for Muscular and Neuronal Function

2000 • 105 citations

Annexin VI-mediated Loss of Spectrin during Coated Pit Budding Is Coupled to Delivery of LDL to Lysosomes

1998 • 102 citations

Drosophila β Spectrin Functions Independently of α Spectrin to Polarize the Na,k Atpase in Epithelial Cells

2000 • 95 citations

Substrate specificities of tyrosine-specific protein kinases toward cytoskeletal proteins in vitro.

1986 • 92 citations

Human α Spectrin II and the Fanconi Anemia Proteins FANCA and FANCC Interact to Form a Nuclear Complex

1999 • 91 citations

Identification of a Candidate Human Spectrin Src Homology 3 Domain-binding Protein Suggests a General Mechanism of Association of Tyrosine Kinases with the Spectrin-based Membrane Skeleton

1998 • 91 citations

Site-Directed Mutagenesis of αII Spectrin at Codon 1175 Modulates Its μ-Calpain Susceptibility

1997 • 83 citations

Proteolytic processing of human brain alpha spectrin (fodrin): identification of a hypersensitive site

1988 • 82 citations

Proteolysis of Platelet Cortactin by Calpain

1997 • 74 citations

Spectrin redistributes to the cytosol and is phosphorylated during mitosis in cultured cells.

1992 • 68 citations

In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s).

1991 • 61 citations

Phosphorylation regulates calpain-mediated truncation of glutamate ionotropic receptors

1998 • 58 citations

Characteristics of a rat cortical collecting duct cell line that maintains high transepithelial resistance

1996 • 56 citations

New insights into functions of erythroid proteins in nonerythroid cells

2000 • 55 citations

Low Molecular Weight Protein-tyrosine Phosphatase Tyrosine Phosphorylation by c-Src during Platelet-derived Growth Factor-induced Mitogenesis Correlates with Its Subcellular Targeting

1998 • 54 citations

The Molecular Basis of the Differing Kinetic Behavior of the Two Low Molecular Mass Phosphotyrosine Protein Phosphatase Isoforms

1996 • 53 citations

Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin 1 1Edited by A. R. Fersht

1999 • 51 citations

Gene Structure, Sequence, and Chromosomal Localization of the Human Red Cell-Type Low-Molecular-Weight Acid Phosphotyrosyl Phosphatase Gene, ACP1

1995 • 48 citations

Calcium/calmodulin inhibits direct binding of spectrin to synaptosomal membranes

1989 • 42 citations

A novel isoform of the low molecular weight phosphotyrosine phosphatase, LMPTP‐C, arising from alternative mRNA splicing

1999 • 27 citations

Spectrin-actin interaction is required for neurite extension in NB 2a/dl neuroblastoma cells

1996 • 26 citations

Insulin Receptor-mediated Dissociation of Grb2 from Sos Involves Phosphorylation of Sos by Kinase(s) Other than Extracellular Signal-regulated Kinase

1998 • 21 citations

Characterization of fodrin phosphorylation by spleen protein tyrosine kinase

1988 • 21 citations

Heterogeneous phosphorylation of erythrocyte spectrin β chain in intact cells

1993 • 13 citations

Characterization of phosphotyrosine containing proteins at the cholinergic synapse

1999 • 12 citations

Brain β‐Spectrin Phosphorylation: Phosphate Analysis and Identification of Threonine‐347 as a Heparin‐Sensitive Protein Kinase Phosphorylation Site

1998 • 11 citations

Method of Site-Directed Mutagenesis Using Long Primer-Unique Site Elimination and Exonuclease III

1997 • 7 citations