Soluble CD-4 and CD-8 as markers of immunological activation in renal transplant recipients

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

1992 • 832 citations

Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy

1996 • 443 citations

Renal Transplantation

1994 • 428 citations

Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes.

1991 • 427 citations

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

1987 • 348 citations

CYCLOSPORINE-INDUCED ACUTE RENAL DYSFUNCTION IN THE RAT EVIDENCE OF ARTERIOLAR VASOCONSTRICTION WITH PRESERVATION OF TUBULAR FUNCTION

1987 • 303 citations

CD4+ but not CD8+ cells are essential for allorejection.

1996 • 303 citations

Soluble CD8 during T cell activation.

1989 • 161 citations

Expression of different CD8 isoforms on distinct human lymphocyte subpopulations

1991 • 159 citations

The renal allograft biopsy

1996 • 156 citations

Association of various T cell-surface molecules with the cytoskeleton. Effect of cross-linking and activation.

1991 • 85 citations

Importance of cytotoxic lymphocytes during cytomegalovirus infection in renal transplant recipients

1984 • 84 citations

Immunochemical analysis of the released Leu-2 (T8) molecule.

1984 • 54 citations

A secreted form of the human lymphocyte cell surface molecule CD8 arises from alternative splicing.

1989 • 52 citations

Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene.

1989 • 52 citations

Soluble CD4 in patients with rheumatoid arthritis and osteoarthritis

1991 • 52 citations

THE USE OF DUPLEX DOPPLER ULTRASONOGRAPHY TO EVALUATE RENAL ALLOGRAFT DYSFUNCTION

1990 • 51 citations

Mechanisms of T lymphocyte activation

1991 • 48 citations

Serum soluble CD4 and CD8 levels in Kawasaki disease

1991 • 45 citations

Increased serum CD8 antigen level in childhood Hodgkin's disease relates to advanced stage and poor treatment outcome

1989 • 45 citations

Soluble CD8 in patients with rheumatic diseases

1990 • 44 citations

A CRITICAL ANALYSIS OF SERUM AND URINE INTERLEUKIN-2 RECEPTOR ASSAYS IN RENAL ALLOGRAFT RECIPIENTS1,2

1989 • 41 citations

Serum levels of CD8 antigen in childhood lymphoid malignancies: a possible indicator of increased suppressor cell activity in poor-risk patients

1988 • 39 citations

Serum soluble CD8 molecule is a marker of CD8 T-cell activation in HIV-1 disease

1991 • 38 citations

MONITORING OF CYTOMEGALOVIRUS INFECTIONS BY THE CD8+CD38+ T-CELL SUBSET IN KIDNEY TRANSPLANT RECIPIENTS

1998 • 36 citations

Serum levels of CD8 antigen in childhood lymphoid malignancies: a possible indicator of increased suppressor cell activity in poor-risk patients

1988 • 33 citations

CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation.

1991 • 30 citations

Elevated levels of CD4 antigen in sera of human immunodeficiency virus-infected populations

1990 • 29 citations

A Distinctive Form of Soluble CD8 Is Secreted by Stimulated CD8+ Cells in HIV-1-Infected and High-Risk Individuals

1994 • 25 citations

Serial flow cytometric analysis of T-cell surface markers can be useful in differential diagnosis of renal allograft dysfunction.

1998 • 25 citations

Increased levels of soluble CD8 and CD4 in patients with infectious mononucleosis

1995 • 25 citations

Do CD4 or CD8 molecules provide a regulatory signal in T-cell activation?

1988 • 23 citations

ANALYSIS OF FINE-NEEDLE ASPIRATION BIOPSIES BY FLOW CYTOMETRY IN KIDNEY TRANSPLANT PATIENTS

1997 • 21 citations

Soluble Interleukin-2 Receptor, Soluble CD8 and Soluble Intercellular Adhesion Molecule-1 Levels in Hematologic Malignancies

1994 • 18 citations

Serum soluble CD4 and CD8 levels in polymyalgia rheumatica.

1994 • 16 citations

Immunologic significance of increased soluble CD8/CD4 molecules in patients with active systemic lupus erythematosus

1993 • 15 citations

Elevated Soluble CD8 Antigen and Soluble Interleukin-2 Receptors in the Sera of Patients with Juvenile Rheumatoid Arthritis

1993 • 15 citations

Value of serum soluble tumour necrosis factor concentrations in the diagnosis and prognosis of renal graft rejection

1994 • 14 citations

RENAL ALLOGRAFT REJECTION IN CD4+ T CELL-RECONSTITUTED ATHYMIC NUDE RATS

1990 • 11 citations

High serum levels of soluble CD8 in insulin-dependent diabetes

1994 • 11 citations

Soluble T lymphocyte markers in the diagnosis of cellular rejection and cytomegalovirus hepatitis in liver transplant recipients

1994 • 9 citations

Soluble CD8 levels in the CSF and serum of patients with multiple sclerosis

1991 • 9 citations

Serum levels of soluble CD4 and CD8 in patients with chronic viral hepatitis.

1994 • 8 citations

Soluble interleukin-2 receptor: a novel parameter of renal graft rejection.

1990 • 6 citations

Soluble CD4: a Link Between Specific Immune Mechanisms and Non‐Specific Inflammatory Responses?

1996 • 5 citations

Monitoring serum IL-2R levels in cadaver renal transplantation: a prospective, blinded study.

1991 • 5 citations

Increased serum CD8 antigen level in childhood Hodgkin's disease relates to advanced stage and poor treatment outcome

1989 • 4 citations

Evaluation of serum immunological parameters in acute renal allograft rejection.

1996 • 4 citations

Predictive value of immunological parameters in the early diagnosis of cytomegalovirus infection in renal transplantation.

1993 • 3 citations