Phorbol ester- and diacylglycerol-mediated desensitization of cardiac beta-adrenergic receptors.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

1970 • 3,269 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol.

1983 • 292 citations

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

1983 • 291 citations

Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake.

1984 • 255 citations

Phorbol diesters promote β-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes

1984 • 238 citations

Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.

1984 • 233 citations

Association of phorbol ester-induced hyperphosphorylation and reversible regulation of transferrin membrane receptors in HL60 cells.

1984 • 225 citations

Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles.

1983 • 191 citations

Tumour promoter uncouples β-adrenergic receptor from adenyl cyclase in mouse epidermis

1980 • 114 citations

Phosphorylation of cardiac sarcolemma proteins by the calcium-activated phospholipid-dependent protein kinase.

1984 • 111 citations

[³H]CGP-12177, A β-Adrenergic Ligand Suitable for Measuring Cell Surface Receptors

1983 • 93 citations

Relationship between an altered membrane form and a low affinity form of the beta-adrenergic receptor occurring during catecholamine-induced desensitization. Evidence for receptor internalization.

1984 • 86 citations

Phosphorylation of cardiac sarcoplasmic reticulum by a calcium-activated, phospholipid-dependent protein kinase

1980 • 82 citations

Involvement of microtubules in the isoproterenol-induced ‘down’-regulation of myocardial β-adrenergic receptors

1983 • 30 citations

Decreased isoproterenol-induced "down"-regulation of beta-adrenergic receptors in the myocardium of SHR.

1984 • 18 citations

Characterization of phorbol diester binding to isolated cardiac myocytes

1985 • 13 citations