Expression of relaxin-like factor is down-regulated in human testicular Leydig cell neoplasia

In situ hybridization; a practical approach

1993 • 1,247 citations

Cloning of a cDNA for a novel insulin-like peptide of the testicular Leydig cells.

1993 • 282 citations

Characterization of Insulin and Insulin-Like Growth Factor I Receptors of Purified Leydig Cells and Their Role in Steroidogenesis in Primary Culture: A Comparative Study*

1986 • 212 citations

Leydig cell hyperplasia and adenoma formation: Mechanisms and relevance to humans

1997 • 133 citations

Direct stimulatory effects of insulin-like growth factor-I on Leydig cell steroidogenesis in primary culture

1986 • 115 citations

Relaxin-Like Factor Gene is Highly Expressed in the Bovine Ovary of the Cycle and Pregnancy: Sequence and Messenger Ribonucleic Acid Analysis1

1996 • 111 citations

A Novel Leydig Cell cDNA-derived Protein Is a Relaxin-like Factor

1995 • 107 citations

Molecular cloning and expression of the relaxin-like factor from the mouse testis.

1996 • 102 citations

Structural Organization of the Porcine and Human Genes Coding for a Leydig Cell-Specific Insulin-like Peptide (LEY I-L) and Chromosomal Localization of the Human Gene (INSL3)

1994 • 102 citations

Cloning of a New Member of the Insulin Gene Superfamily (INSL4) Expressed in Human Placenta

1995 • 101 citations

Combination of the peroxidase anti-peroxidase (PAP)-and avidin-biotin-peroxidase complex (ABC)-techniques: an amplification alternative in immunocytochemical staining

1990 • 101 citations

Relaxin-like factor: a highly specific and constitutive new marker for Leydig cells in the human testis

1997 • 100 citations

Relaxin Binds to and Elicits a Response from Cells of the Human Monocytic Cell Line, THP-1

1996 • 97 citations

Expression of the relaxin gene in rat tissues

1995 • 83 citations

Demonstration of a direct carcinogenic effect of estradiol on Leydig cells of the mouse.

1980 • 69 citations

Regulation of insulin-like growth factor-I messenger ribonucleic acid expression in Leydig cells

1990 • 65 citations

Biology of the relaxin-like factor (RLF)

1997 • 55 citations

The human Leydig insulin-like (hLEY I-L) gene is expressed in the corpus luteum and trophoblast.

1995 • 54 citations

Detection of Shiga toxin-producing Shigella dysenteriae type 1 and Escherichia coli by using polymerase chain reaction with incorporation of digoxigenin-11-dUTP

1991 • 46 citations

Sex determination, differentiation and intersexuality in placental mammals

1996 • 43 citations

Immunohistological determination of oestrogen receptor, progesterone receptor, and intermediate filaments in Leydig cell tumours, Leydig cell hyperplasia, and normal Leydig cells of the human testis

1989 • 39 citations

Relaxin Increases Insulin-Like Growth Factors (IGFs) and IGF-Binding Proteins of the Pig Uterusin Vivo¹

1997 • 24 citations

Leydig Cell Tumor and Metachronous Leydig Cellhyperplasia: A Case Associated With Gynecomastia and Elevated Urinary Estrogens

1986 • 19 citations

Leydig cell hyperplasia in cryptorchid patients: Quantitative evaluation of Leydig cells in undescended and contralateral scrotal testes

1984 • 17 citations

Relaxin-Induced Deoxyribonucleic Acid Synthesis in Porcine Granulosa Cells is Mediated by Insulin-Like Growth Factor-I1

1995 • 17 citations

Expression of SQ10 (a Preprorelaxin-Like Gene) in the Pregnant Rabbit Placenta and Uterus1

1995 • 12 citations

Lack of Influence of Hypophysectomy on Estrogen-Induced DNA Synthesis in Leydig Cells of BALB/c Mice2

1977 • 11 citations

Increase in testis luteinizing hormone receptor by estrogen in mice susceptible to Leydig cell tumors.

1981 • 10 citations

Differentiation of the gonads

1995 • 5 citations