Antiviral Effects of Plasma and Milk Proteins: Lactoferrin Shows Potent Activity against Both Human Immunodeficiency Virus and Human Cytomegalovirus Replication In Vitro

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Colorimetric Method for Determination of Sugars and Related Substances

1956 • 48,885 citations

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1989 • 3,477 citations

Determination of free amino groups in proteins by trinitrobenzenesulfonic acid

1966 • 2,029 citations

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

1988 • 1,634 citations

The Cytomegaloviruses: Ubiquitous Agents with Protean Clinical Manifestations

1971 • 649 citations

Antibacterial spectrum of lactoferricin B, a potent bactericidal peptide derived from the N‐terminal region of bovine lactoferrin

1992 • 573 citations

Human lactotransferrin: amino acid sequence and structural comparisons with other transferrins

1984 • 531 citations

Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment

1993 • 494 citations

Prevalence of Cytomegalovirus Infection in Homosexual Men

1981 • 440 citations

The uses and properties of PEG-linked proteins.

1992 • 425 citations

Initiation of Human Cytomegalovirus Infection Requires Initial Interaction with Cell Surface Heparan Sulfate

1993 • 422 citations

Breast Milk and the Risk of Cytomegalovirus Infection

1980 • 373 citations

Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus.

1987 • 317 citations

Cytomegalovirus Infection of Breast Milk and Transmission in Infancy

1983 • 302 citations

Enzymatic conversion of proteins to glycoproteins.

1977 • 295 citations

Anti-infective properties of breast milk

1979 • 290 citations

Bidirectional Interactions Between Human Immunodeficiency Virus Type 1 and Cytomegalovirus

1988 • 274 citations

Molecular cloning and sequence analysis of bovine lactotransferrin

1991 • 244 citations

Human cytomegalovirus penetrates host cells by PH-independent fusion at the cell surface

1992 • 222 citations

Killing of Candida albicans by lactoferricin B, a potent antimicrobial peptide derived from the N-terminal region of bovine lactoferrin

1993 • 219 citations

Type C Virus-Producing Cell Lines Derived from Adult T Cell Leukemia

1982 • 215 citations

Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region

1993 • 205 citations

Lactoferrin, lactoferrin receptors and iron metabolism.

1993 • 180 citations

A human cytomegalovirus glycoprotein complex designated gC-II is a major heparin-binding component of the envelope

1992 • 165 citations

Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate

1992 • 162 citations

The lower matrix protein pp65 is the principal viral antigen present in peripheral blood leukocytes during an active cytomegalovirus infection

1992 • 145 citations

CD13 (human aminopeptidase N) mediates human cytomegalovirus infection

1993 • 140 citations

Complete nucleotide sequence of human mammary gland lactoferrin

1990 • 139 citations

The fungicidal effect of human lactoferrin on Candida albicans and Candida krusei

1993 • 109 citations

Bovine lactoferrin mRNA: Sequence, analysis, and expression in the mammary gland

1991 • 105 citations

ANTIVIRAL ACTIVITY IN MILK OF POSSIBLE CLINICAL IMPORTANCE

1976 • 105 citations

The role of lactoferrin in the bactericidal function of polymorphonuclear leucocytes.

1979 • 100 citations

Role of cell-binding in the antibacterial mechanism of lactoferricin B.

1993 • 90 citations

Plasma lactoferrin reflects granulocyte activation in vivo

1983 • 83 citations

Nucleotide sequence of human lactoferrin cDNA

1990 • 80 citations

Ultrastructural Analysis of Circulating Cytomegalic Cells in Patients with Active Cytomegalovirus Infection: Evidence for Virus Production and Endothelial Origin

1993 • 79 citations

Expression of a human cytomegalovirus receptor correlates with infectibility of cells

1991 • 75 citations

Structure, composition and heparin binding properties of a human cytomegalovirus glycoprotein complex designated gC-II

1993 • 74 citations

Heparin-binding properties of lactoferrin and lysozyme

1992 • 63 citations

Monoclonal Antibody E-13 (M-810) to Human Cytomegalovirus Recognizes an Epitope Encoded by Exon 2 of the Major Immediate Early Gene

1992 • 62 citations

Potent in vitro anti-human immunodeficiency virus-1 activity of modified human serum albumins.

1991 • 60 citations

Cytomegaloviruses of man and animals.

1973 • 54 citations

Lactoferrin receptors in piglet small intestine: Lactoferrin binding properties, ontogeny, and regional distribution in the gastrointestinal tract

1993 • 50 citations

Novel, negatively charged, human serum albumins display potent and selective in vitro anti-human immunodeficiency virus type 1 activity.

1993 • 49 citations

The DNA-binding protein P52 of human cytomegalovirus reacts with monoclonal antibody CCH2 and associates with the nuclear membrane at late times after infection

1992 • 38 citations

Plasma lactoferrin reflects granulocyte activation via complement in burn patients.

1984 • 30 citations

Inhibitory Effects of Polycations on the Replication of Enveloped Viruses (HIV, HSV, CMV, RSV, Influenza A Virus and Togaviruses) in vitro

1991 • 19 citations

Inhibition of human cytomegalovirus major immediate early gene expression by antisense RNA expression vectors

1993 • 16 citations

Plasma lactoferrin content: Differential effect of steroid administration and infective illnesses: Lack of effect of ambient temperature at which specimens are collected

1986 • 11 citations

Cellular receptor for human cytomegalovirus.

1991 • 9 citations

Strategies for the treatment of cytomegalovirus infections

1993 • 3 citations