Genetic analysis of the mouse X inactivation center defines an 80-kb multifunction domain

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

1991 • 1,469 citations

Requirement for Xist in X chromosome inactivation

1996 • 995 citations

XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure.

1996 • 787 citations

Reactivation of an Inactive Human X Chromosome: Evidence for X Inactivation by DNA Methylation

1981 • 711 citations

Xist-deficient mice are defective in dosage compensation but not spermatogenesis.

1997 • 705 citations

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

1993 • 692 citations

MAMMALIAN X-CHROMOSOME INACTIVATION

1983 • 635 citations

Genetic variants and strains of the Laboratory mouse

1996 • 500 citations

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

1989 • 434 citations

Synthetic activities during spermatogenesis in the mouse

1965 • 419 citations

Fluorescence in situ hybridization: applications in cytogenetics and gene mapping

1991 • 375 citations

Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation

1993 • 369 citations

A 450 kb Transgene Displays Properties of the Mammalian X-Inactivation Center

1996 • 315 citations

Long-range cis effects of ectopic X-inactivation centres on a mouse autosome

1997 • 268 citations

Fluorescence in situ hybridization: applications in cytogenetics and gene mapping

1991 • 262 citations

Xist has properties of the X-chromosome inactivation centre

1997 • 248 citations

X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation

1985 • 208 citations

Physical mapping of large DNA by chromosome fragmentation.

1988 • 170 citations

Role of the region 3′ to Xist exon 6 in the counting process of X-chromosome inactivation

1998 • 168 citations

X–chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro

1978 • 133 citations

The Spreading of X Inactivation into Autosomal Material of an X;autosome Translocation: Evidence for a Difference between Autosomal and X-Chromosomal DNA

1998 • 130 citations

X-Autosome Translocations in The Mouse: Total Inactivation Versus Partial Inactivation Of The X Chromosome

1970 • 115 citations

Inheritance of Glucose-6-phosphate Dehydrogenase Variation in Kangaroos

1971 • 105 citations

Construction of a large-insert yeast artificial chromosome library of the rat genome

1997 • 92 citations

Developmentally Regulated Xist Promoter Switch Mediates Initiation of X Inactivation

1998 • 82 citations

The search for the mouse X-chromosome inactivation centre

1990 • 80 citations

The (epi)genetic control of mammalian X-chromosome inactivation

1997 • 79 citations

Identification and characterization of the human XIST gene promoter: implications for models of X chromosome inactivation

1997 • 79 citations

Construction of a large-insert yeast artificial chromosome library of the mouse genome

1993 • 75 citations

Transgenic mice carrying an Xist-containing YAC

1996 • 73 citations

DELAYED ONSET OF REPLICATION OF HUMAN X CHROMOSOMES

1967 • 68 citations

The role of Xist in X-inactivation

1998 • 66 citations

Analysis of spreading of inactivation in eight X autosome translocations utilizing the high resolution RBG technique

1986 • 50 citations

Xist expression from an Xist YAC transgene carried on the mouse Y chromosome

1996 • 37 citations

A Method for High Efficiency YAC Lipofection into Murine Embryonic Stem Cells

1996 • 30 citations

Regulatory elements in the minimal promoter region of the mouse Xist gene

1997 • 30 citations

Characterization of the promoter region of the mouse Xist gene.

1995 • 24 citations