Diversity of the class II (I-Ak/I-Ek)-restricted T cell repertoire for influenza hemagglutinin and antigenic drift. Six nonoverlapping epitopes on the HA1 subunit are defined by synthetic peptides.

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

1981 • 2,490 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

1985 • 1,650 citations

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

1981 • 1,603 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

The Relation Between Major Histocompatibility Complex (MHC) Restriction and the Capacity of Ia to Bind Immunogenic Peptides

1987 • 696 citations

Prediction of immunodominant helper T cell antigenic sites from the primary sequence.

1987 • 483 citations

Isolation and characterization of antigen-la complexes involved in T cell recognition

1986 • 470 citations

Future influenza vaccines and the use of genetic recombinants.

1969 • 386 citations

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1987 • 367 citations

Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.

1984 • 351 citations

Antigenic drift in influenza virus H3 hemagglutinin from 1968 to 1980: multiple evolutionary pathways and sequential amino acid changes at key antigenic sites

1983 • 324 citations

Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas.

1984 • 175 citations

The Structure of T-Cell Epitopes

1987 • 130 citations

Influences of antigen processing on the expression of the T cell repertoire. Evidence for MHC-specific hindering structures on the products of processing.

1988 • 129 citations

Mapping of Antigenic Changes in the Haemagglutinin of Hong Kong Influenza (H3N2) Strains using a Large Panel of Monoclonal Antibodies

1982 • 113 citations

Molecular mapping of a histocompatibility-restricted immunodominant T cell epitope with synthetic and natural peptides: implications for T cell antigenic structure.

1986 • 105 citations

Characterization of the murine TH response to influenza virus hemagglutinin: evidence for three major specificities.

1984 • 99 citations

"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.

1985 • 98 citations

Participation of the major histocompatibility complex in antibody recognition of viral antigens expressed on infected cells.

1982 • 81 citations

The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.

1986 • 78 citations

Distinct recognition phenotypes exist for T cell clones specific for small peptide regions of proteins. Implications for the mechanisms underlying major histocompatibility complex-restricted antigen recognition and clonal deletion models of immune response gene defects.

1985 • 74 citations

Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens.

1987 • 65 citations

Processing of a minimal antigenic peptide alters its interaction with MHC molecules

1988 • 63 citations

Extensive diversity in the recognition of influenza virus hemagglutinin by murine T helper clones.

1986 • 50 citations

The beta 1 domain of the mouse E beta chain is important for restricted antigen presentation to helper T-cell hybridomas.

1985 • 29 citations

Searching for MHC‐restricted anti‐viral antibodies: antibodies recognizing the nucleoprotein of influenza virus dominate the serological response of C57BL/6 mice to syngeneic influenza‐infected cells

1987 • 24 citations

Fine specificity of murine class II-restricted T cell clones for synthetic peptides of influenza virus hemagglutinin. Heterogeneity of antigen interaction with the T cell and the Ia molecule.

1988 • 24 citations

Distinct epitopes recognized by I-Ad-restricted T-cell clones within antigenic site E on influenza virus hemagglutinin

1988 • 21 citations