Sedation and analgesia

Controlled Sedation with Alphaxalone-Alphadolone

1974 • 2,804 citations

Opioid analgesics and antagonists

1996 • 1,193 citations

Hyperalgesia Mediated by Spinal Glutamate or Substance P Receptor Blocked by Spinal Cyclooxygenase Inhibition

1992 • 725 citations

Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports.

1992 • 572 citations

Clinical Pharmacokinetics of Fentanyl and its Newer Derivatives

1983 • 375 citations

Prolonged sedation due to accumulation of conjugated metabolites of midazolam

1995 • 323 citations

Postoperative Analgesia Using Epidural Infusions of Fentanyl with Bupivacaine

1995 • 216 citations

A Review of the Clinical Pharmacokinetics of Meloxicam

1996 • 199 citations

Failure of critically ill patients to metabolise midazolam

1987 • 192 citations

A comparison of remifentanil and alfentanil in patients undergoing major abdominal surgery

1997 • 181 citations

Mortality amongst multiple trauma patients admitted to an intensive therapy unit

1983 • 179 citations

Drug Dosage in Patients during Continuous Renal Replacement Therapy

1993 • 155 citations

The techniques used to sedate ventilated patients

1981 • 136 citations

DISPOSITION OF PROPOFOL IN PATIENTS UNDERGOING SURGERY

1986 • 128 citations

Propofol infusion for sedation in intensive care

1987 • 126 citations

Acetylsalicylic acid, paracetamol and morphine inhibit behavioral responses to intrathecally administered substance P or capsaicin

1985 • 91 citations

The Use of Sedative Agents in Critically Ill Patients

1992 • 81 citations

Sedatives, Analgesics, and Paralytics in the Icu

1997 • 79 citations

Plasma Inorganic Fluoride Concentrations During and After Prolonged (>24 h) Isoflurane Sedation

1991 • 68 citations

EFFECT OF PROPOFOL ON PERIPHERAL VASCULAR RESISTANCE DURING CARDIOPULMONARY BYPASS

1990 • 59 citations

The Modifying Effect of General and Regional Anesthesia on the Endocrine-metabolic Response to Surgery

1982 • 57 citations

Metabolism of remifentanil during liver transplantation

1998 • 52 citations

EXTRAHEPATIC MORPHINE METABOLISM IN MAN DURING THE ANHEPATIC PHASE OF ORTHOTOPIC LIVER TRANSPLANTATION

1989 • 51 citations

PHARMACOKINETICS OF MORPHINE IN TWO CHILDREN BEFORE AND AFTER LIVER TRANSPLANTATION

1986 • 38 citations

Extra‐hepatic metabolism of midazolam.

1989 • 30 citations

Continuous monitoring of depth of sedation by EEG spectral analysis in patients requiring mechanical ventilation

1994 • 28 citations

Alfentanil Infusions in Patients Requiring Intensive Care

1988 • 24 citations

Sedation, analgesia and muscle relaxation and the critically ill patient

1997 • 11 citations

INTENSIVE CARE

1996 • 9 citations

Sedation in Intensive Care

1991 • 8 citations

Renal replacement therapy for the critically ill--precarious progress. Part II. Technical aspects and clinical application.

1993 • 6 citations

[Ventilation modes and strategies in intensive care medicine].

1997 • 4 citations

Clonidine: old friend--new guises.

1990 • 4 citations

What makes acute pain chronic?

1997 • 4 citations

New trends in the basic science of pain

1997 • 1 citations