TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 • 4,529 citations

The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

2017 • 4,003 citations

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

2001 • 1,659 citations

Foxp3⁺CD25⁺CD4⁺ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

2006 • 1,535 citations

Inducing and expanding regulatory T cell populations by foreign antigen

2005 • 1,245 citations

FOXP3: Of Mice and Men

2005 • 929 citations

Origin of regulatory T cells with known specificity for antigen

2002 • 854 citations

In Vivo Instruction of Suppressor Commitment in Naive T Cells

2004 • 726 citations

Following a diabetogenic T cell from genesis through pathogenesis

1993 • 708 citations

Recognition of the Peripheral Self by Naturally Arising CD25+ CD4+ T Cell Receptors

2004 • 690 citations

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

2006 • 523 citations

Initiation of Autoimmune Diabetes by Developmentally Regulated Presentation of Islet Cell Antigens in the Pancreatic Lymph Nodes

1999 • 426 citations

Developmental regulation of Foxp3 expression during ontogeny

2005 • 418 citations

Induction offoxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants

2004 • 416 citations

CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion

2004 • 373 citations

β cell apoptosis in T cell-mediated autoimmune diabetes

1997 • 330 citations

Origin and T Cell Receptor Diversity of Foxp3+CD4+CD25+ T Cells

2006 • 316 citations

Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen

2005 • 296 citations

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

2005 • 266 citations

Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells

2004 • 238 citations

The role of the transcription factor Foxp3 in the development of regulatory T cells

2006 • 181 citations

Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4+ T Cells

2007 • 178 citations

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

2001 • 166 citations

Genetic Control of Diabetes Progression

1997 • 148 citations

The Shaping of the T Cell Repertoire

2001 • 134 citations

Allelic Inclusion of T Cell Receptor α Genes Poses an Autoimmune Hazard Due to Low-Level Expression of Autospecific Receptors

1998 • 129 citations

What do TCR–pMHC crystal structures teach us about MHC restriction and alloreactivity?

2003 • 121 citations

Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

2006 • 95 citations

Regulation of Diabetes Development by Regulatory T Cells in Pancreatic Islet Antigen-Specific TCR Transgenic Nonobese Diabetic Mice

2002 • 70 citations

B-cell apoptosis in T-cell-mediated autoimmune diabetes

2009 • 54 citations

The same genomic region conditions clonal deletion and clonal deviation to the CD8αα and regulatory T cell lineages in NOD versus C57BL/6 mice

2007 • 18 citations