The pharmacokinetics in mice and dogs of nitroimidazole radiosensitizers and chemosensitizers more lipophilic than misonidazole

Partition Coefficient as a Guide to the Development of Radiosensitizers Which Are Less Toxic Than Misonidazole

1980 • 214 citations

Estimation of the hypoxic cell-sensitiser misonidazole and its O-demethylated metabolite in biological materials by reversed-phase high-performance liquid chromatography

1978 • 93 citations

Structure-pharmacokinetic relationships for misonidazole analogues in mice

1981 • 62 citations

The Pharmacokinetics and Tumor and Neural Tissue Penetrating Properties of SR-2508 and SR-2555 in the Dog-Hydrophilic Radiosensitizers Potentially Less Toxic than Misonidazole

1980 • 53 citations

Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: Structure-activity relationships

1982 • 27 citations

Effect of lipophilicity of nitroimidazoles on radiosensitization of hypoxic bacterial cells in vitro

1979 • 26 citations

Improved procedure for the determination of niridazole in biological fluids by high-performance liquid chromatography

1978 • 11 citations