Soluble Tumor Necrosis Factor (TNF) Receptors p55 and p75 and Interleukin-10 Downregulate TNF- α Activity during the Lung Response to Silica Particles in NMRI Mice

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

1997 • 3,094 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

TUMOR NECROSIS FACTOR: A Pleiotropic Cytokine and Therapuetic Target

1994 • 1,047 citations

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.

1996 • 920 citations

Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia.

1993 • 821 citations

Inflammatory cytokines in cystic fibrosis lungs.

1995 • 702 citations

Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis

1990 • 581 citations

Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10

1992 • 516 citations

Shedding of tumor necrosis factor receptors by activated human neutrophils.

1990 • 443 citations

Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.

1995 • 364 citations

Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure.

1993 • 329 citations

Lung Particle Overload: Implications for Occupational Exposures to Particles

1995 • 291 citations

Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice

1994 • 287 citations

Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor

1993 • 280 citations

Production of Interleukin 13 by Alveolar Macrophages from Normal and Fibrotic Lung

1998 • 266 citations

Health Effects of Mineral Dusts

1993 • 266 citations

Pulmonary Response to Silica or Titanium Dioxide: Inflammatory Cells, Alveolar Macrophage-derived Cytokines, and Histopathology

1990 • 249 citations

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction.

1996 • 213 citations

A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA)

1995 • 204 citations

Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the Fc epsilon RI. Role for mast cell-derived transforming growth factor beta and tumor necrosis factor alpha.

1994 • 190 citations

Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice.

1997 • 183 citations

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

1995 • 163 citations

Reactive oxygen intermediates as regulators of TNF-alpha production in rat lung inflammation induced by silica.

1996 • 162 citations

Slow release of soluble TNF receptors by monocytes in vitro.

1994 • 150 citations

Regulation of monokine gene expression: prostaglandin E2 suppresses tumor necrosis factor but not interleukin-1 alpha or beta-mRNA and cell-associated bioactivity.

1989 • 149 citations

Intercellular adhesion molecule-1 gene expression by glial cells. Differential mechanisms of inhibition by IL-10 and IL-6.

1995 • 134 citations

TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosis.

1996 • 125 citations

Role of Interleukin-10 in the Lung Response to Silica in Mice

1998 • 123 citations

Regulation of Monokine Gene Expression: Prostaglandin E2 Suppresses Tumor Necrosis Factor but Not Interleukin-1α or β-mRNA and Cell-Associated Bioactivity

1989 • 115 citations

Interleukin-4 and -13 Inhibit Tumor Necrosis Factor-α mRNA Translational Activation in Lipopolysaccharide-induced Mouse Macrophages

1997 • 111 citations

Regulation of surface and soluble TNF receptor expression on human monocytes and synovial fluid macrophages by IL-4 and IL-10.

1996 • 102 citations

Spontaneous and Stimulated Release of Tumor Necrosis Factor-alpha (TNF) from Blood Monocytes of Miners with Coal Workers' Pneumoconiosis

1988 • 100 citations

Transforming growth factor-beta (TGF-beta) in silicosis.

1996 • 99 citations

Altered accessory cell function of alveolar macrophages: a possible mechanism for induction of Th2 secretory profile in idiopathic pulmonary fibrosis

1997 • 88 citations

Immunohistochemical localization of transforming growth factor-beta 1 in rats with experimental silicosis, alveolar type II hyperplasia, and lung cancer.

1993 • 82 citations

Abnormal Secretion of Interleukin-1 and Tumor Necrosis Factor α by Alveolar Macrophages in Coal Worker's Pneumoconiosis: Comparison between Simple Pneumoconiosis and Progressive Massive Fibrosis

1990 • 76 citations

Role of tumor necrosis factor-alpha in the spontaneous development of pulmonary fibrosis in viable motheaten mutant mice.

1997 • 64 citations

Constitutive shedding of both p55 and p75 murine TNF receptors in vivo.

1997 • 61 citations

Increased susceptibility to silicosis and TNF-alpha production in C57BL/6J mice.

1995 • 52 citations

Lung Toxicity of Hard Metal Particles and Production of Interleukin-1, Tumor Necrosis Factor-α, Fibronectin, and Cystatin-c by Lung Phagocytes

1995 • 49 citations

Resistance of TNF/LTα double deficient mice to bleomycin‐induced fibrosis

1997 • 45 citations

Role of Urokinase in the Fibrogenic Response of the Lung to Mineral Particles

1998 • 44 citations

Biological studies on the carcinogenic mechanisms of quartz

1993 • 32 citations

Enhanced Release of Prostaglandin E₂ from Macrophages of Rats with Silicosis

1992 • 32 citations

Enzymatic degradation of tumor necrosis factor by activated human neutrophils: Role of elastase

1991 • 32 citations

Engagement of Tumor Necrosis Factor mRNA by an Endotoxin-Inducible Cytoplasmic Protein

1996 • 26 citations

Neutrophils activated by granulocyte colony-stimulating factor suppress tumor necrosis factor-alpha release from monocytes stimulated by endotoxin.

1995 • 25 citations

Defective translation of tumor necrosis factor mRNA in lipopolysaccharide-tolerant macrophages.

1996 • 23 citations

Plasma levels of soluble tumour necrosis factor receptors are increased in coal miners with pneumoconiosis

1995 • 21 citations

Bidirectional modulation of TNF-α production by alveolar macrophages in asbestos-induced pulmonary fibrosis

1993 • 15 citations

Administration of anti-TNF-alpha or anti-CD11a antibodies to normal adult mice decreases lung and bone collagen content: evidence for an effect on platelet consumption.

1995 • 12 citations

Role of Interleukin-10 (IL-10) in the lung response to silica in mice.

1997 • 8 citations