Monoclonal antibodies to the carbohydrate structure Lewisx stimulate the adhesive activity of leukocyte integrin CD11b/CD18 (CR3, Mac-1, αmβ2) on human granulocytes
Data up to Jan 2025
Total Citations Per Year
Abstract
References (43)
Recognition by Elam-1 of the Sialyl-Le x Determinant on Myeloid and Tumor Cells
1990 • 976 citations
Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule
1989 • 973 citations
GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases
1991 • 848 citations
CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.
1991 • 505 citations
The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.
1986 • 487 citations
A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1
1991 • 480 citations
Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies.
1986 • 423 citations
PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15)
1990 • 367 citations
Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils.
1991 • 347 citations
ELFT: A gene that directs the expression of an ELAM-1 ligand
1990 • 338 citations
CD62/P-selectin recognition of myeloid and tumor cell sulfatides
1991 • 304 citations
Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion.
1991 • 281 citations
Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit
1991 • 262 citations
A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.
1988 • 248 citations
GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interaction.
1991 • 247 citations
Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: Homophilic and heterophilic adhesion
1989 • 236 citations
Carbohydrate ligands for endothelial-leukocyte adhesion molecule 1.
1991 • 236 citations
Antibody against the Leu-CAM beta-chain (CD18) promotes both LFA-1- and CR3-dependent adhesion events.
1992 • 223 citations
The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.
1991 • 175 citations
Myeloid differentiation antigen defined by a monoclonal antibody
1981 • 171 citations
CD66 nonspecific cross-reacting antigens are involved in neutrophil adherence to cytokine-activated endothelial cells.
1992 • 168 citations
Up-regulation of the iC3b receptor (CR3) is neither necessary nor sufficient to promote neutrophil aggregation.
1988 • 161 citations
P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.
1992 • 160 citations
Cloning of a human alpha(1,3)-fucosyltransferase gene that encodes ELFT but does not confer ELAM-1 recognition on Chinese hamster ovary cell transfectants.
1991 • 160 citations
Dissociation between increased surface expression of gp165/95 and homotypic neutrophil aggregation.
1988 • 156 citations
Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules.
1990 • 155 citations
Neutrophil Activation in Thermal Injury as Assessed by Increased Expression of Complement Receptors
1986 • 151 citations
Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Lea and sialosyl-Lex, and sulfated glycans modulate this binding
1991 • 134 citations
2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages II. Dissociation of the inhibitory effects of 2-deoxyglucose on phagocytosis and ATP generation.
1976 • 123 citations
A specific heterotypic cell adhesion activity between members of carcinoembryonic antigen family, W272 and NCA, is mediated by N-domains
1991 • 110 citations
A novel carbohydrate, differentiation antigen on fucogangliosides of human myeloid cells recognized by monoclonal antibody VIM-2.
1988 • 108 citations
M2, A novel myelomonocytic cell surface antigen and its distribution on leukemic cells
1984 • 106 citations
Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated platelets
1990 • 102 citations
Neutrophil Aggregation Induced by Sera from Patients with Active Systemic Lupus Erythematosus
1983 • 77 citations
CD66 identifies a neutrophil-specific epitope within the hematopoietic system that is expressed by members of the carcinoembryonic antigen family of adhesion molecules
1991 • 70 citations
Expression of the CD15 differentiation antigen (3-fucosyl-N-acetyl-lactosamine, LeX) on putative neutrophil adhesion molecules CR3 and NCA-160
1990 • 69 citations
An improved semi-quantitative enzyme immunostaining procedure for glycosphingolipid antigens on high performance thin layer chromatograms
1986 • 68 citations
Two pathways of CD11b/CD18-mediated neutrophil aggregation with different involvement of protein kinase C-dependent phosphorylation.
1990 • 67 citations
Continuous cell activation is necessary for stable interaction of complement receptor type 3 with its counter‐structure in the aggregation response of human neutrophils
1990 • 49 citations
Binding of nonspecific cross-reacting antigen, a granulocyte membrane glycoprotein, to Escherichia coli expressing type 1 fimbriae
1991 • 45 citations
CD15 antibodies increase neutrophil adhesion to endothelium by an LFA‐1‐dependent mechanism
1989 • 37 citations
CD66 monoclonal antibodies recognize a phosphotyrosine-containing protein bearing a carcinoembryonic antigen cross-reacting antigen on the surface of human neutrophils.
1992 • 36 citations
Differences in the fine specificities of monoclonal (Class A) antibodies to human myeloid cells.
1985 • 21 citations