The effect of polyoma virus, serum factors, and dibutyryl cyclic AMP on dihydrofolate reductase synthesis, and the entry of quiescent cells into S phase

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Restoration of Several Morphological Characteristics of Normal Fibroblasts in Sarcoma Cells Treated with Adenosine-3′:5′-Cyclic Monophosphate and Its Derivatives

1971 • 440 citations

THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATION

1967 • 421 citations

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.

1978 • 393 citations

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.

1979 • 376 citations

INDUCTION OF CELLULAR DNA SYNTHESIS BY POLYOMA VIRUS

1965 • 304 citations

Growth Control and Cyclic Alterations of Cyclic AMP in the Cell Cycle

1972 • 292 citations

A Novel Chromosome Abnormality in Human Neuroblastoma and Antifolate-Resistant Chinese Hamster Cell Lines in Culture 1 2

1976 • 213 citations

Messenger RNA turnover in mouse L cells

1973 • 201 citations

Histone Synthesis in Vitro on HeLa Cell Microsomes

1969 • 198 citations

Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells.

1979 • 185 citations

Synthesis and degradation of folate reductase in sensitive and methotrexate-resistant lines of S-180 cells.

1976 • 171 citations

EFFECT OF ADENOSINE 3'-5'-CYCLIC MONOPHOSPHATE ON CELL PROLIFERATION

1972 • 151 citations

Autoradiography. Techniques and Application.

1970 • 140 citations

A temperature‐sensitive cell cycle mutant of the BHK cell line

1974 • 132 citations

Adenyl Cyclase in Normal and Transformed Fibroblasts in Tissue Culture

1971 • 124 citations

Cyclic nucleotides in cultured cells.

1975 • 122 citations

Control of DNA synthesis and mitosis in 3T3 cells by cyclic AMP

1972 • 117 citations

c-AMP and the cell cycle: Inhibition of growth stimulation

1973 • 103 citations

Regulation of folate reductase synthesis in sensitive and methotrexate-resistant sarcoma 180 cells. In vitro translation and characterization of folate reductase mRNA.

1976 • 97 citations

Regulation of dihydrofolate reductase gene expression in mouse fibroblasts during the transition from the resting to growing state

1978 • 89 citations

Polyoma virus and cyclic AMP-mediated control of dihydrofolate reductase mRNA abundance in methotrexate-resistant mouse fibroblasts.

1979 • 89 citations

Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.

1967 • 74 citations

Deoxyribonucleic Acid Replication in Simian Virus 40-Infected Cells

1970 • 72 citations

Conditions Leading to Enhanced Response to Glucagon, Epinephrine, or Prostaglandins by Adenylate Cyclase of Normal and Malignant Cultured Cells

1971 • 68 citations

Induction of dihydrofolate reductase activity by SV40 and polyoma virus.

1966 • 66 citations

INHIBITION OF CELL GROWTH IN THE G1 PHASE BY ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE

1974 • 66 citations

Regulation of dihydrofolate reductase synthesis in an overproducing 3T6 cell line during transition from resting to growing state

1979 • 59 citations

Cyclic 3′:5′ AMP and cell proliferation in cultures of embryonic rat cells

1972 • 59 citations

Deoxyribonucleic acid synthesis in cells replicating polyoma virus

1966 • 56 citations

Glycoprotein synthesis in a temperature‐sensitive Chinese hamster cell cycle mutant

1977 • 44 citations

Studies on a chinese hamster line that is temperature sensitive for the commitment to DNA synthesis

1974 • 31 citations

Resistance of resting 3T6 mouse fibroblasts to methotrexate cytotoxicity.

1978 • 27 citations

Autoradiography: Techniques and Applications

1970 • 26 citations

Alteration of Methotrexate by leukemic cells: loss of affinity for an anion exchange resin.

1969 • 15 citations