Intrastriatal Transforming Growth Factor α Delivery to a Model of Parkinson's Disease Induces Proliferation and Migration of Endogenous Adult Neural Progenitor Cells without Differentiation into Dopaminergic Neurons

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

1999 • 3,822 citations

CNS stem cells express a new class of intermediate filament protein

1990 • 3,138 citations

Convergence of Wnt, ß-Catenin, and Cadherin Pathways

2004 • 2,451 citations

Transient expression of doublecortin during adult neurogenesis

2003 • 1,485 citations

Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

2004 • 1,261 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

2002 • 1,179 citations

Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis

2000 • 1,064 citations

EGF Converts Transit-Amplifying Neurogenic Precursors in the Adult Brain into Multipotent Stem Cells

2002 • 1,030 citations

A unified hypothesis on the lineage of neural stem cells

2001 • 976 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain

1996 • 757 citations

Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain

2000 • 716 citations

Cell Proliferation Without Neurogenesis in Adult Primate Neocortex

2001 • 714 citations

Regeneration of a germinal layer in the adult mammalian brain

1999 • 638 citations

A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin

1991 • 632 citations

Short‐term and long‐term survival of new neurons in the rat dentate gyrus

2003 • 616 citations

Evidence for neurogenesis in the adult mammalian substantia nigra

2003 • 577 citations

New aspects of Wnt signaling pathways in higher vertebrates

2001 • 550 citations

Regulation of neurogenesis by growth factors and neurotransmitters

1998 • 483 citations

Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone

2000 • 476 citations

β-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

2003 • 463 citations

Transforming Growth Factor-α Null and Senescent Mice Show Decreased Neural Progenitor Cell Proliferation in the Forebrain Subependyma

1997 • 442 citations

Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model.

1979 • 436 citations

In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain

2000 • 412 citations

Direct Evidence for Homotypic, Glia-Independent Neuronal Migration

1997 • 410 citations

Stimulation of Neonatal and Adult Brain Neurogenesis by Subcutaneous Injection of Basic Fibroblast Growth Factor

1999 • 375 citations

Adult Neurogenesis in Mammals: An Identity Crisis

2002 • 303 citations

Is it all DNA repair?

2002 • 294 citations

Elusive radial glial cells: Historical and evolutionary perspective

2003 • 271 citations

Nestin expression in pancreatic stellate cells and angiogenic endothelial cells

2002 • 215 citations

Dopamine Modulates Cell Cycle in the Lateral Ganglionic Eminence

2003 • 191 citations

Repeated Cocaine Modifies the Mechanism by which Amphetamine Releases Dopamine

1997 • 178 citations

ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.

2002 • 174 citations

Adenovirally Expressed Noggin and Brain-Derived Neurotrophic Factor Cooperate to Induce New Medium Spiny Neurons from Resident Progenitor Cells in the Adult Striatal Ventricular Zone

2004 • 170 citations

Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissues

1988 • 163 citations

Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain

1997 • 160 citations

EGFRs mediate chemotactic migration in the developing telencephalon

2001 • 123 citations

Proliferative zones of postnatal rat brain express epidermal growth factor receptor mRNA

1995 • 117 citations

A null mutation in TGF-α leads to a reduction in midbrain dopaminergic neurons in the substantia nigra

1998 • 97 citations

Growth factor treatment promotes mobilization of young but not aged adult subventricular zone precursors in response to demyelination

2002 • 60 citations

Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat

2001 • 54 citations

Tangential migration of young neurons arising from the subventricular zone of adult rats is impaired by surgical lesions passing through their natural migratory pathway

1999 • 48 citations

Expression of bone morphogenetic proteins in the brain during normal aging and in 6-hydroxydopamine-lesioned animals

2003 • 47 citations

Intracerebral Transplantation of Testis-Derived Sertoli Cells Promotes Functional Recovery in Female Rats with 6-Hydroxydopamine-Induced Hemiparkinsonism

1997 • 36 citations

Parkinsonian Motor Deficits Are Reflected by Proportional A9/A10 Dopamine Neuron Degeneration in the Rat

2001 • 31 citations