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Food-Related Illness and Death in the United States

1999 • 7,361 citations

Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures

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Molecular cloning (2nd Ed)

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Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.

1992 • 1,086 citations

X-ray Crystallographic Structure of the Norwalk Virus Capsid

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Expression, self-assembly, and antigenicity of the Norwalk virus capsid protein

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Sequence and Genomic Organization of Norwalk Virus

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Norwalk-like viruses

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Immunization with viruslike particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection

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Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice.

1996 • 577 citations

Candidemia in Allogeneic Blood and Marrow Transplant Recipients: Evolution of Risk Factors after the Adoption of Prophylactic Fluconazole

2000 • 506 citations

Human Immune Responses to a Novel Norwalk Virus Vaccine Delivered in Transgenic Potatoes

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Molecular Epidemiology of “Norwalk‐like Viruses” in Outbreaks of Gastroenteritis in the United States

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Replicon-Helper Systems from Attenuated Venezuelan Equine Encephalitis Virus: Expression of Heterologous Genesin Vitroand Immunization against Heterologous Pathogensin Vivo

1997 • 440 citations

Vaccination Strategies for Mucosal Immune Responses

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The Epidemiology of Enteric Caliciviruses from Humans: A Reassessment Using New Diagnostics

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Multiple-Challenge Study of Host Susceptibility to Norwalk Gastroenteritis in US Adults

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Norwalk Virus Open Reading Frame 3 Encodes a Minor Structural Protein

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Marburg Virus Vaccines Based upon Alphavirus Replicons Protect Guinea Pigs and Nonhuman Primates

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Recombinant Norwalk virus–like particles given orally to volunteers: Phase I study

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Mutations in the E2 Glycoprotein of Venezuelan Equine Encephalitis Virus Confer Heparan Sulfate Interaction, Low Morbidity, and Rapid Clearance from Blood of Mice

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Comparison of the reactivities of baculovirus-expressed recombinant Norwalk virus capsid antigen with those of the native Norwalk virus antigen in serologic assays and some epidemiologic observations

1993 • 217 citations

Genetic polymorphism across regions of the three open reading frames of "Norwalk-like viruses"

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Vaccination of Macaques against Pathogenic Simian Immunodeficiency Virus with Venezuelan Equine Encephalitis Virus Replicon Particles

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Recombinant RNA replicons derived from attenuated Venezuelan equine encephalitis virus protect guinea pigs and mice from Ebola hemorrhagic fever virus

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Molecular Epidemiology of Human Enteric Caliciviruses in The Netherlands

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Human papillomavirus type 16 virus-like particles expressed in attenuated Salmonella typhimurium elicit mucosal and systemic neutralizing antibodies in mice

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Organization and Expression of Calicivirus Genes

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Synthesis and assembly of virus-like particles of human papillomaviruses type 6and Type 16 in fission yeast Schizosaccharomyces pombe

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Oral Immunization with Recombinant Norwalk Virus-Like Particles Induces a Systemic and Mucosal Immune Response in Mice

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Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: Construction of single and multiple mutants in a full-length cDNA clone

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Transmission of Norwalk Virus during a Football Game

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Molecular Cloning and Expression of Major Structural Protein VP1 of the Human Polyomavirus JC Virus: Formation of Virus-Like Particles Useful for Immunological and Therapeutic Studies

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Proteins of Norwalk virus

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Recombinant Norwalk Virus-Like Particles Administered Intranasally to Mice Induce Systemic and Mucosal (Fecal and Vaginal) Immune Responses

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Virus-Like Particles As A Rotavirus Subunit Vaccine

1996 • 123 citations

Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector

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Biochemical characterization of a smaller form of recombinant Norwalk virus capsids assembled in insect cells

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Attenuated Mutants of Venezuelan Equine Encephalitis Virus Containing Lethal Mutations in the PE2 Cleavage Signal Combined with a Second-Site Suppressor Mutation in E1

1995 • 115 citations

Alphavirus vectors for gene expression and vaccines

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A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge

1996 • 110 citations

Capsid protein diversity among Norwalk-like viruses.

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Antigenic Mapping of the Recombinant Norwalk Virus Capsid Protein Using Monoclonal Antibodies

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Immunity to Calicivirus Infection

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Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector

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Specific proteolytic cleavage of recombinant Norwalk virus capsid protein

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Heterotypic protection from rotavirus infection in mice vaccinated with virus-like particles

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Norwalk Virus Vaccines: Challenges and Progress

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Heterotypic Protection and Induction of a Broad Heterotypic Neutralization Response by Rotavirus-Like Particles

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Papillomavirus-like particle vaccines for cervical cancer

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Immunization with DNA, adenovirus or both in biodegradable alginate microspheres: effect of route of inoculation on immune response

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Construction, Expression, and Immunogenicity of Chimeric HIV-1 Virus-like Particles

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Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate

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Molecular Epidemiology of Human Enteric Caliciviruses in The Netherlands

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Venezuelan equine encephalitis virus vectors expressing HIV-1 proteins: vector design strategies for improved vaccine efficacy

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Nucleocapsid- and virus-like particles assemble in cells infected with recombinant baculoviruses or vaccinia viruses expressing the M and the S segments of Hantaan virus

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Venezuelan equine encephalitis virus vaccines induce mucosal IgA responses and protection from airborne infection in BALB/c, but not C3H/HeN mice

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Mucosal Immunity Induced by Parenteral Immunization with a Live Attenuated Venezuelan Equine Encephalitis Virus Vaccine Candidate

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Norwalk-Like Viral Gastroenteritis Outbreak in U.S. Army Trainees

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Complete Nucleotide Sequence of the Chiba Virus Genome and Functional Expression of the 3C-Like Protease in Escherichia coli

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Genomic diversity of ?Norwalk like viruses? (NLVs): Pediatric infections in a Brazilian shantytown

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Safety and Immunogenicity of Recombinant Human Immunodeficiency Virus-Like Particles in Rodents and Rhesus Macaques

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Differences in the post‐translational modifications of human papillomavirus type 6b major capsid protein expressed from a baculovirus system compared with a vaccinia virus system

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Glycosylation of synthetic T helper cell epitopic peptides influences their antigenic potency and conformation in a sugar location-specific manner

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The effects of post-translational side-chain modifications on the stimulatory activity, serum stability and conformation of synthetic peptides carrying T helper cell epitopes

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Posttranslational side chain modification of a viral epitope results in diminished recognition by specific T cells

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Norwalk virus infection in Venezuela

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A new model system to study Norwalk virus immunity

1999 • 7 citations