Structure of haemoglobin in the deoxy quaternary state with ligand bound at the α haems

Methods in Enzymology , Vol

1966 • 26,261 citations

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

1970 • 2,874 citations

Traitement statistique des erreurs dans la determination des structures cristallines

1952 • 1,284 citations

Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism

1979 • 862 citations

The crystal structure of human deoxyhaemoglobin at 1.74 Å resolution

1984 • 738 citations

Structure and refinement of oxymyoglobin at 1·6 Å resolution

1980 • 641 citations

Structure of human oxyhaemoglobin at 2·1resolution

1983 • 618 citations

X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 Å resolution

1986 • 511 citations

Neutron diffraction reveals oxygen–histidine hydrogen bond in oxymyoglobin

1981 • 449 citations

Stereochemistry of cooperative mechanisms in hemoglobin

1987 • 414 citations

Refinement of large structures by simultaneous minimization of energy and R factor

1978 • 354 citations

Hemoglobin as a receptor of drugs and peptides: x-ray studies of the stereochemistry of binding

1986 • 290 citations

The role of the distal histidine in myoglobin and haemoglobin

1988 • 288 citations

The structure of human carbonmonoxy haemoglobin at 2.7 Å resolution

1980 • 271 citations

Preparation of Haemoglobin crystals

1968 • 266 citations

Studies on Cytochrome c Peroxidase

1967 • 259 citations

Studies on Cobalt Myoglobins and Hemoglobins

1974 • 214 citations

Resonance Raman investigation of carbon monoxide bonding in (carbon monoxy)hemoglobin and -myoglobin: detection of iron-carbon monoxide stretching and iron-carbon-oxygen bending vibrations and influence of the quaternary structure change

1982 • 181 citations

Hemoglobin tertiary structural change on ligand binding its role in the co-operative mechanism

1983 • 173 citations

Tailoring the pH dependence of enzyme catalysis using protein engineering

1985 • 168 citations

Real space refinement of neutron diffraction data from sperm whale carbonmonoxymyoglobin

1981 • 161 citations

Relation between structure, co-operativity and spectra in a model of hemoglobin action

1973 • 160 citations

PH dependence of the Adair constants of human hemoglobin. Nonuniform contribution of successive oxygen bindings to the alkaline Bohr effect.

1975 • 143 citations

Three-dimensional structure of abnormal human haemoglobins M Hyde Park and M Iwate

1971 • 105 citations

BEZAFIBRATE LOWERS OXYGEN AFFINITY OF HAEMOGLOBIN

1983 • 102 citations

Bonding of molecular oxygen to T state human haemoglobin

1984 • 100 citations

Structure of the liganded T state of haemoglobin identifies the origin of cooperative oxygen binding

1988 • 88 citations

Synthesis and coordination properties of superstructured iron-porphyrins

1986 • 74 citations

Intermediate structure of normal human haemoglobin: Methaemoglobin in the deoxy quaternary conformation

1973 • 72 citations

Structures of deoxy and carbonmonoxy haemoglobin Kansas in the deoxy quaternary conformation

1975 • 71 citations

Oxygen equilibrium study and light absorption spectra of Ni(II)Fe(II) hybrid hemoglobins

1986 • 62 citations

Properties of chemically modified Ni(II)Fe(II) hybrid hemoglobins

1986 • 58 citations

Structure of human fluoromethaemoglobin with inositol hexaphosphate

1977 • 55 citations

Resonance Raman evidence for cleavage of the Fe-N.epsilon.(His-F8) bond in the .alpha. subunit of the T-structure nitrosylhemoglobin

1980 • 50 citations

Changes in pKa values of individual histidine residues of human hemoglobin upon reaction with carbon monoxide

1980 • 49 citations

X-ray diffraction studies of a partially liganded hemoglobin, [α(FeII-CO)β(MnII)]2

1986 • 48 citations

Preparation and proton nuclear magnetic resonance investigation of cross-linked mixed valency hybrid hemoglobins: models for partially oxygenated species

1982 • 46 citations

Influence of DPG on the bohr effect of human hemoglobin

1974 • 44 citations

Proton nuclear magnetic resonance and spectrophotometric studies of nickel(II)-iron(II) hybrid hemoglobins

1987 • 42 citations

Structure of human deoxy cobalt haemoglobin

1982 • 34 citations

Response of the Bohr group salt bridges to ligation of the T state of haemoglobin Kansas

1978 • 33 citations

HIGH‐RESOLUTION PROTON NMR STUDIES OF LOW AFFINITY HEMOGLOBINS

1973 • 23 citations

Effect of Removal of a Salt-Bridge on the Oxygen Binding Properties and the Electronic Structure of Heme in Cobalt-Iron Hybrid Hemoglobin

1979 • 10 citations

Nonequivalence in the electronic structure of the prosthetic groups between two alpha-subunits within deoxycobalthemoglobin as determined by single-crystal EPR spectroscopy.

1986 • 4 citations