Formation of glycine receptor clusters and their accumulation at synapses

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination

1993 • 2,272 citations

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

1995 • 1,861 citations

Mechanism of anion permeation through channels gated by glycine and gamma‐aminobutyric acid in mouse cultured spinal neurones.

1987 • 1,166 citations

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

1998 • 1,147 citations

Homer: a protein that selectively binds metabotropic glutamate receptors

1997 • 1,058 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors

1997 • 866 citations

Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin

1998 • 846 citations

Segregation of Different GABA_AReceptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells

1998 • 829 citations

The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

1987 • 730 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton

1999 • 722 citations

Heteromultimerization and NMDA Receptor-Clustering Activity of Chapsyn-110, a Member of the PSD-95 Family of Proteins

1996 • 539 citations

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

1995 • 530 citations

Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons

1993 • 446 citations

Dual Requirement for Gephyrin in Glycine Receptor Clustering and Molybdoenzyme Activity

1998 • 436 citations

Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization

1994 • 420 citations

Identification of a gephyrin binding motif on the glycine receptor β subunit

1995 • 410 citations

Heterogeneity in the Molecular Composition of Excitatory Postsynaptic Sites during Development of Hippocampal Neurons in Culture

1998 • 396 citations

Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer.

1988 • 388 citations

Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord

1996 • 383 citations

Distribution of glycine receptors at central synapses: an immunoelectron microscopy study.

1985 • 358 citations

Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord.

1984 • 335 citations

Nonsynaptic Glycine Receptor Activation during Early Neocortical Development

1998 • 316 citations

Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein

1992 • 307 citations

The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels.

1992 • 305 citations

Molecular mechanisms of glutamate receptor clustering at excitatory synapses

1998 • 273 citations

The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton

1995 • 273 citations

Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

1990 • 272 citations

The 93-kDa glycine receptor-associated protein binds to tubulin.

1991 • 268 citations

Glycine-receptor activation is required for receptor clustering in spinal neurons

1998 • 267 citations

Selective clustering of glutamate and gamma-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmitters.

1994 • 239 citations

Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers.

1993 • 239 citations

Cloning and expression of the 58 kd β subunit of the inhibitory glycine receptor

1990 • 237 citations

Glycine receptors: heterogeneous and widespread in the mammalian brain

1991 • 232 citations

gamma-Aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses

1987 • 224 citations

Redistribution and Stabilization of Cell Surface Glutamate Receptors during Synapse Formation

1997 • 207 citations

Identification of glycinergic synapses in the cochlear nucleus through immunocytochemical localization of the postsynaptic receptor

1986 • 207 citations

The Mr 93,000 polypeptide of the postsynaptic glycine receptor complex is a peripheral membrane protein

1987 • 187 citations

Regulation of Ion Channel Distribution at Synapses

1993 • 177 citations

Both NMDA and non-NMDA subtypes of glutamate receptors are concentrated at synapses on cerebral cortical neurons in culture

1991 • 172 citations

Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

1989 • 159 citations

Biogenesis of epithelial cell polarity: Intracellular sorting and vectorial exocytosis of an apical plasma membrane glycoprotein

1984 • 157 citations

Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptor

1989 • 151 citations

Intracellular sorting and basolateral appearance of the G protein of vesicular stomatitis virus in Madin-Darby canine kidney cells.

1985 • 145 citations

Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptor

1991 • 143 citations

Biochemical Aspects of Transmission at Inhibitory Synapses: The Role of Glycine

1978 • 136 citations

Targeting of Glycine Receptor Subunits to Gephyrin-Rich Domains in Transfected Human Embryonic Kidney Cells

1995 • 132 citations

Organization and regulation of proteins at synapses

1999 • 130 citations

Strychnine-sensitive stabilization of postsynaptic glycine receptor clusters

1998 • 95 citations

Synaptic Control of Glycine and GABA_AReceptors and Gephyrin Expression in Cultured Motoneurons

1999 • 94 citations

Differential subcellular distribution of the α6 subunit versus the α1 and β2/3 subunits of the GABAA/benzodiazepine receptor complex in granule cells of the cerebellar cortex

1992 • 90 citations

Genetic analysis of postsynaptic differentiation at the vertebrate neuromuscular junction

1997 • 72 citations

Expression of Glycine Receptor α Subunits and Gephyrin in Cultured Spinal Neurons

1996 • 65 citations

Adenovirus enhancement of polyethylenimine-mediated transfer of regulated genes in differentiated cells

1997 • 64 citations

Acetylcholine receptors are not functionally independent

1986 • 63 citations

Biology of the Postsynaptic Glycine Receptor

1997 • 61 citations

Rapsyn Clusters Neuronal Acetylcholine Receptors But Is Inessential for Formation of an Interneuronal Cholinergic Synapse

1998 • 57 citations

Localization of components of glycinergic synapses during rat spinal cord development.

1998 • 53 citations

Pharmacological Evidence for Two Types of Postsynaptic Glycinergic Receptors on the Mauthner Cell of 52-h-Old Zebrafish Larvae

1997 • 52 citations

Review : Glycine Receptors: Molecular Heterogeneity and Implications for Disease

1995 • 47 citations

Localization of components of glycinergic synapses during rat spinal cord development

1998 • 43 citations

Development of glycine receptor alpha subunit in cultivated rat spinal neurons: An immunocytochemical study

1992 • 39 citations

Gephyrin accumulates at specific plasmalemma loci during neuronal maturation in vitro

1996 • 31 citations

Efficient Transfer of Regulated Genes in Adipocytes and Hepatoma Cells by the Combination of Liposomes and Replication‐Deficient Adenovirus

1996 • 24 citations

Adult-type glycine receptors form clusters on embryonic rat spinal cord neurons developing in vitro

1993 • 23 citations

Incorporation of a gephyrin‐binding motif targets NMDA receptors to gephyrin‐rich domains in HEK 293 cells

1999 • 19 citations

Modulation by NMDA Receptor Antagonists of Glycine Receptor Isoform Expression in Cultured Spinal Cord Neurons

1992 • 16 citations

Immunogenicity of a Synthetic Peptide Corresponding to a Portion of the Heavy Chain of H3N2 Influenza Virus Haemagglutinin

1987 • 11 citations