Role of the Mononuclear Phagocyte System in the Development of Acquired Immunodeficiency Syndrome (AIDS)

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

Pneumocystis cariniiPneumonia and Mucosal Candidiasis in Previously Healthy Homosexual Men

1981 • 2,717 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

The Role of Mononuclear Phagocytes in HTLV-III/LAV Infection

1986 • 1,828 citations

Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy

1986 • 1,694 citations

An Outbreak of Community-AcquiredPneumocystis cariniiPneumonia

1981 • 1,433 citations

Isolation of Lymphocytopathic Retroviruses from San Francisco Patients with AIDS

1984 • 1,429 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

1986 • 804 citations

Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization.

1986 • 740 citations

Pulmonary Complications of the Acquired Immunodeficiency Syndrome

1984 • 698 citations

Infection of monocyte/macrophages by human T lymphotropic virus type III.

1986 • 682 citations

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein

1986 • 593 citations

Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus

1985 • 572 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

AIDS Retrovirus Induced Cytopathology: Giant Cell Formation and Involvement of CD4 antigen

1986 • 516 citations

Impaired Production of Lymphokines and Immune (Gamma) Interferon in the Acquired Immunodeficiency Syndrome

1984 • 513 citations

Human Immunodeficiency Viruses

1986 • 476 citations

Acquired Immunodeficiency Syndrome in Infants

1984 • 433 citations

Epidermal Langerhans Cells-A Target for HTLV-III/LAV Infection

1987 • 414 citations

Sequence Homology and Morphologic Similarity of HTLV-III and Visna Virus, a Pathogenic Lentivirus

1985 • 407 citations

Immunohistochemical identification of HTLV‐III antigen in brains of patients with AIDS

1986 • 380 citations

Tropism of sheep lentiviruses for monocytes: susceptibility to infection and virus gene expression increase during maturation of monocytes to macrophages

1986 • 342 citations

A Trojan Horse mechanism for the spread of visna virus in monocytes

1985 • 340 citations

Human T lymphotropic virus type III infection of human alveolar macrophages

1986 • 309 citations

Virus Isolation From and Identification of HTLV-III/LAV-Producing Cells in Brain Tissue From a Patient With AIDS

1986 • 302 citations

Monocyte function in the acquired immune deficiency syndrome. Defective chemotaxis.

1984 • 299 citations

Slow Virus Replication: the Role of Macrophages in the Persistence and Expression of Visna Viruses of Sheep and Goats

1982 • 283 citations

FOLLICULAR DENDRITIC CELLS AND VIRUS-LIKE PARTICLES IN AIDS-RELATED LYMPHADENOPATHY

1984 • 283 citations

Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and T-cell infectivity.

1986 • 261 citations

Lentiviral Diseases of Sheep and Goats: Chronic Pneumonia Leukoencephalomyelitis and Arthritis

1985 • 251 citations

Nucleotide sequence evidence for relationship of AIDS retrovirus to lentiviruses

1985 • 242 citations

Activation of caprine arthritis-encephalitis virus expression during maturation of monocytes to macrophages

1983 • 240 citations

Human T-cell lymphotropic virus type III infection of the central nervous system. A preliminary in situ analysis

1986 • 238 citations

Lymphocytic Interstitial Pneumonitis

1978 • 207 citations

Amplification of HTLV-III/LAV infection by antigen-induced activation of T cells and direct suppression by virus of lymphocyte blastogenic responses.

1987 • 194 citations

Detection of HTLV-III RNA in Lungs of Patients With AIDS and Pulmonary Involvement

1986 • 187 citations

Equine Infectious Anemia Virus: Immunopathogenesis and Persistence

1985 • 186 citations

HTLV-III expression in infected lymph nodes and relevance to pathogenesis of lymphadenopathy.

1986 • 155 citations

Isolation of infectious human T-cell leukemia/lymphotropic virus type III (HTLV-III) from patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) and from healthy carriers: a study of risk groups and tissue sources.

1985 • 146 citations

Pulmonary Involvement in the Acquired Immunodeficiency Syndrome

1985 • 145 citations

Blood Monocyte and Neutrophil Functions in the Acquired Immune Deficiency Syndrome

1986 • 141 citations

In vitro modification of human immunodeficiency virus infection by granulocyte-macrophage colony-stimulating factor and gamma interferon.

1986 • 133 citations

Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gamma.

1985 • 129 citations

CD4 receptor binding peptides that block HIV infectivity cause human monocyte chemotaxis

1987 • 125 citations

Decreased expression of human class II antigens on monocytes from patients with acquired immune deficiency syndrome. Increased expression with interferon-gamma.

1984 • 106 citations

Determinants of Susceptibility and Resistance to Feline Leukemia Virus Infection. I. Role of Macrophages23

1981 • 83 citations

Immunologic abnormalities in the acquired immunodeficiency syndrome (AIDS).

1984 • 82 citations

Pathology of Suspected Acquired Immune Deficiency Syndrome in Children: A Study of Eight Cases

1984 • 81 citations

Early Defect of Phagocytic Cell Function in Subjects at Risk for Acquired Immunodeficiency Syndrome

1986 • 80 citations

Interleukin 1 inhibitor masks high interleukin 1 production in acquired immunodeficiency syndrome (AIDS)

1987 • 79 citations

Immunohistopathology of lymph nodes in HTLV-III infected homosexuals with persistent adenopathy or AIDS.

1985 • 68 citations

Defective Reticuloendothelial System Fc-Receptor Function in Patients with Acquired Immunodeficiency Syndrome

1985 • 67 citations

LAV-like viral particles in lymph node germinal centers in patients with the persstent lymphadenopathy syndrome and the acquired immunodeficiency syndrome-related complex: An ultrastructural study of 30 cases

1986 • 59 citations

Immunohistochemical demonstration of p24 HTLV III major core protein in different cell types within lymph nodes from patients with lymphadenopathy syndrome (LAS)

1986 • 51 citations

Infection of macrophages with friend virus: Relationship to the spontaneous regression of viral erythroleukemia

1979 • 45 citations

Altered functions of peripheral blood monocytes in homosexual males and intravenous drug users with persistent generalized lymphadenopathy

1986 • 40 citations

Quantitative analysis of visna virus replication in Vivo

1985 • 33 citations

Impaired mononuclear-cell proliferation in patients with the acquired immune deficiency syndrome results from abnormalities of both T lymphocytes and adherent mononuclear cells

1985 • 29 citations

Immunological Studies in the Acquired Immunodeficiency Syndrome

1986 • 28 citations

Serum Amyloid Protein A (SAA): An Indicator of Inflammation in AIDS and AIDS-related Complex (ARC)

1986 • 24 citations

Acquired immune deficiency syndrome: An overview of central nervous system complications and neuropsychological sequelae

1986 • 23 citations

Impaired monocyte-to-macrophage maturation in patients with lymphadenopathy syndrome

1986 • 10 citations

Involvement of macrophage-like cells in growth of tumors induced by avian sarcoma virus.

1983 • 7 citations